Breast MRI: MRI Evaluation of the Breast Areolar Margin and Paryenchyma
Study Details
Study Description
Brief Summary
The purpose of this study is to test a new method of defining patterns of how breast glands are or are not attached to the overlying skin. All patients will have markers placed on both breasts and will undergo an MRI. MRI results will be examined to identify the pattern of breast gland attachment to the overlying skin. This will help identify patients which may benefit from areolar sparing and/or nipple sparing technique and which patients should be treated by standard mastectomy.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
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N/A |
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Other: MRI All patients on study will undergo an MRI of the breast(s). |
Other: MRI
Patients who qualify for the study and consent to be included will undergo placement of areola and nipple markers that will be held in place with tape for the duration of the ordered MRI study. The markers consist of latex-free plastic tubing filled with vegetable based hydrogenated oil that is solid at room temperature. This creates a fat density marker that will define the areola but does not interfere with or create artifact onto the underlying tissue. The marker can be placed by the investigator or available MRI technician instructed in marker placement. The patient will then undergo the MRI. The patients participation in the study will end with the MRI.
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Outcome Measures
Primary Outcome Measures
- Patterns of Breast Gland Attachment [6 months]
Identify the various patterns of breast gland attachment to the overlying skin.
Eligibility Criteria
Criteria
Inclusion Criteria:
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Have one of the following indications for MRI study of the breast - screening for high risk without evidence of disease, have existing breast cancer with need for evaluation of extent of disease or to rule out additional occult cancer, or to have an equivocal mammogram or ultrasound requiring additional information from MRI.
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No prior breast surgery including prior excisional biopsies for disease performed with surgical technique, breast augmentation, reduction mammoplasty or breast lift with or without implants.
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Capable of fitting into the MRI machine.
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Permission to contact and consent the patient to participate from the investigator(s)
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Provide written informed consent and Authorization for Use/Disclosure of PHI
Exclusion Criteria:
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Have a contraindication to MRI study.
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Prior breast surgery - this includes: prior excisional biopsies for disease performed with surgical technique, breast augmentation, reduction mammoplasty or breast lift with or without implants [Patients may have undergone prior percutaneous (needle) biopsy or fine needle aspiration]
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Inability to fit into the MRI machine.
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Psychological factors that may interfere with successful completion of the study
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Refusal to provide written informed consent and/or Authorization for Use/Disclosure of PHI
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Piedmont Hospital | Atlanta | Georgia | United States | 30309 |
Sponsors and Collaborators
- Piedmont Healthcare
Investigators
- Principal Investigator: Heather Richardson, MD, Piedmont Hospital
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- Breast MRI