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COMPRIM: Use of Compressed Sensing in Breast MRI

Sponsor
Institut de Cancérologie de Lorraine (Other)
Overall Status
Completed
CT.gov ID
NCT02826369
Collaborator
(none)
13
Enrollment
1
Location
1
Arm
14
Actual Duration (Days)
28.3
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Breast MRI is increasingly important in breast screening imaging. It is currently based on dynamic sequences after contrast injection whose temporal resolution must be less than 90 seconds with dynamic acquisitions at different times.

These curves profiles are designed to differentiate benign from malignant lesions. Recently, Mann et al, (2014) showed that increasing the temporal resolution of dynamic acquisitions; lesion enhancement curves over time were more accurate than the curves usually performed.

It seems necessary to work on sequences having better temporal resolution without compromising however spatial resolution.

Condition or Disease Intervention/Treatment Phase
  • Other: 3.0 Tesla in Magnetic Resonance Imaging
 N/A

Study Design

Study Type:
Interventional
Actual Enrollment :
13 participants
Allocation:
N/A
Intervention Model:
Single Group Assignment
Masking:
None (Open Label)
Primary Purpose:
Other
Official Title:
Use of Compressed Sensing in Breast MRI
Actual Study Start Date :
Mar 29, 2016
Actual Primary Completion Date :
Apr 12, 2016
Actual Study Completion Date :
Apr 12, 2016

Arms and Interventions

Arm Intervention/Treatment
Experimental: 3.0 Tesla in Magnetic Resonance Imaging

Other: 3.0 Tesla in Magnetic Resonance Imaging
Eligible patient will have a standard MRI. The images taken before 4min30 and after 6min after to the injection of gadolimium contrast medium will be carried out with the standard image acquisition. The images taken between 4min30 and 6min after the injection of gadolimium contrast medium will be carried out with the compressed sensing image acquisition.

Outcome Measures

Primary Outcome Measures

  1. Agreement between compressed sensing and standard image acquisition [1 day]

    Agreement between compressed sensing and standard image acquisition is defined by percentage of lesions detected by both modes of acquisitions

Secondary Outcome Measures

  1. Analysis of dammage contours [1 day]

    Analysis of lesions contours will be performed according to Bi-RADS classification

  2. Image quality in compressed sensing acquisition [1 day]

    The image quality will be evaluated using a quality scale

Eligibility Criteria

Criteria

Ages Eligible for Study:
N/A to 18 Years
Sexes Eligible for Study:
Female
Accepts Healthy Volunteers:
No
Inclusion Criteria:

  • Patient to benefit a MRI in the assessment for a breast carcinoma

  • Age >18 years old

  • Assessment on 3.0 Tesla in Magnetic Resonance Imaging

  • ECOG performance status ≤ 3

  • Ability to provide an informed written consent form

Exclusion Criteria:

  • Age < 18 years old

  • Claustrophobia

  • Contraindication to the injection of gadolinium contrast medium

  • Contraindication to MRI

  • Persons deprived of liberty or under supervision

Contacts and Locations

Locations

Site City State Country Postal Code
1 Institut de Cancérologie de Lorraine Vandoeuvre-Lès -Nancy France 54500

Sponsors and Collaborators

  • Institut de Cancérologie de Lorraine

Investigators

  • Principal Investigator: OLDRINI Guillaume, MD, Institut de Cancérologie de Lorraine

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Institut de Cancérologie de Lorraine
ClinicalTrials.gov Identifier:
NCT02826369
Other Study ID Numbers:
  • 2015-A00581-48
First Posted:
Jul 11, 2016
Last Update Posted:
Aug 8, 2018
Last Verified:
Aug 1, 2018
Individual Participant Data (IPD) Sharing Statement:
No
Plan to Share IPD:
No
Keywords provided by Institut de Cancérologie de Lorraine
Algorithms
Image Processing, Computer-Assisted/methods*
Magnetic Resonance Imaging/methods*
Data Compression
Breast Neoplasms

Study Results

No Results Posted as of Aug 8, 2018