Social Media Listening in Improving Clinical Trial Recruitment in Patients With Cancer

Sponsor

University of Southern California (Other)

Overall Status

Withdrawn

CT.gov ID

NCT03408561

Collaborator

National Cancer Institute (NCI) (NIH)

Enrollment

Location

Arm

13.7

Anticipated Duration (Months)

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

This pilot clinical trial studies how well social media listening works in improving clinical trial recruitment in patients with cancer. Social media listening and recruitment on Twitter may enhance enrollment for cancer-related clinical trials.

Condition or Disease	Intervention/Treatment	Phase
Breast Carcinoma Colon Carcinoma Kidney Carcinoma Lymphoma Non-Small Cell Lung Carcinoma Prostate Carcinoma	Other: Internet-Based Intervention Other: Survey Administration	N/A

Detailed Description

PRIMARY OBJECTIVES:

Examine the feasibility (acceptance among University of Southern California [USC] Norris study team members and Twitter users in Los Angeles [LA] county) of targeted social media listening (SML) via Twitter as a tool for enhancing recruitment to cancer trials.
Gain preliminary data on the impact (i.e., numbers recruited versus projected accrual compared to historic recruitment) of targeted social media listening (SML) as a tool for enhancing recruitment to cancer trials among Twitter users in LA county.
Estimate the effect size of the number of people enrolled associated with the use of targeted social media listening (SML) via Twitter as a tool for enhancing recruitment to cancer trials.

OUTLINE:

Patients who mention specific cancer disease keywords and/or hashtags are identified and receive a message via Twitter. Patients are then contacted for recruitment into a clinical trial.

Study Design

Study Type:

Interventional

Actual Enrollment :

0 participants

Allocation:

N/A

Intervention Model:

Single Group Assignment

Masking:

None (Open Label)

Primary Purpose:

Health Services Research

Official Title:

The Use of Social Media Listening for Targeted Recruitment of Twitter Users in LA County in Cancer Trials Compared to Historic Recruitment Data: A Mixed-Methods Study

Actual Study Start Date :

Nov 8, 2017

Anticipated Primary Completion Date :

Dec 31, 2018

Anticipated Study Completion Date :

Dec 31, 2018

Arms and Interventions

Arm	Intervention/Treatment
Experimental: Health Services Research (message via Twitter) Patients who mention specific cancer disease keywords and/or hashtags are identified and receive a message via Twitter. Patients are then contacted for recruitment into a clinical trial.	Other: Internet-Based Intervention Receive message via Twitter Other: Survey Administration Ancillary studies

Arm

Intervention/Treatment

Experimental: Health Services Research (message via Twitter)

Patients who mention specific cancer disease keywords and/or hashtags are identified and receive a message via Twitter. Patients are then contacted for recruitment into a clinical trial.

Other: Internet-Based Intervention

Receive message via Twitter

Other: Survey Administration

Ancillary studies

Outcome Measures

Primary Outcome Measures

User acceptance and satisfaction with social media (SM) as a recruitment method [Up to 14 months]
A questionnaire will be used assess the acceptance of and satisfaction with SM recruitment method among University of Southern California (USC) Norris study team members and Twitter users in Los Angeles (LA) county.
Accrual rate [Up to 14 months]
To be determined by comparing monthly actual versus (vs.) projected rate of recruitment for the trial disease groups (i.e., non-small cell lung cancer, colon cancer, breast cancer, prostate cancer, kidney cancer, lymphoma) using generalized estimating equations, accounting for intra-disease random effects and trends across the 12 months (9 months exposure per trial). These results will then be put into context of the historic recruitment for these diseases at the center.

Eligibility Criteria

Criteria

Ages Eligible for Study:

N/A and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion Criteria:

TRIAL INCLUSION:
Focus on one of the following disease categories: non-small cell lung cancer, colon cancer, breast cancer, prostate cancer, kidney cancer, lymphoma
Be a phase 1 trial in expansion, phase 2, or 3
Be interventional trials
Recruit in English
Be Institutional Review Board (IRB)-approved and open to accrual at USC Norris
Recruit for at least 9 months at the point of enrollment
Set monthly accrual target >= 1/ and annual accrual target >= 12
PATIENT INCLUSION:
Will include all prospective trial participants in this study that come from Twitter in response of our SM recruitment interventions, provided they meet the specific trial's eligibility criteria

Exclusion Criteria:

TRIAL EXCLUSION:
Phase 1 trials in dose escalation
PATIENT EXCLUSION:
Persons who do not meet the eligibility criteria of any of the trials open to accrual will be excluded from participation, and persons who may be eligible (e.g., disease/histology, stage, prior treatment) but do not meet additional trial-specific requirements such as insurance or allergy to drug)