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Bronchi Dilation in Polynesian Patients: Monocentric Retrospective Study

Sponsor
Centre Hospitalier Intercommunal Creteil (Other)
Overall Status
Not yet recruiting
CT.gov ID
NCT04798950
Collaborator
(none)
500
Enrollment
5.9
Anticipated Duration (Months)

Study Details

Study Description

Brief Summary

The study hypothesis is that dilations of idiopathic bronchi are particularly common in French Polynesia, and that there are arguments in favour of an underlying genetic factor.

The study will retrieve retrospective data in the history of bronchial dilation, patients' personal and family history, microbiological and scannographic data, and the latest cardio respiratory checkup.

Condition or Disease Intervention/Treatment Phase

    Study Design

    Study Type:
    Observational
    Anticipated Enrollment :
    500 participants
    Observational Model:
    Cohort
    Time Perspective:
    Retrospective
    Official Title:
    Bronchi Dilation in Polynesian Patients: Monocentric Retrospective Study
    Anticipated Study Start Date :
    Jan 1, 2022
    Anticipated Primary Completion Date :
    Jan 1, 2022
    Anticipated Study Completion Date :
    Jul 1, 2022

    Outcome Measures

    Primary Outcome Measures

    1. Describe the detailed phenotype of bronchi dilation in the Polynesian population [Day 1]

      Clinical criteria: age of onset, personal or family history, smoking Changes in respiratory function Infectious complications: types of bronchial colonization (bacterial, mycobacterial and mycological) Scantographic aspect: Appearance of bronchectasis: cylindrical, varicose orcious, cystic Distributions: LSD, LM, LID, LSG, LIG

    Secondary Outcome Measures

    1. Highlighting indirect arguments for a genetic cause [Day 1]

      Age of onset of symptoms, frequency of so-called "idiopathic" bronchi dilatation, frequency of inbreeding, familial history

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    18 Years and Older
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    No
    Inclusion Criteria:

    • Polynesian patient

    • Patient with bronchial dilation followed by Centre hospitalier de Polynesie Francaise or patient with bonchial dilation no longer consulting in the hospital over the study period Jan 1, 2010 to Dec 31, 2020

    Exclusion Criteria:
    • Expressed refusal to participate in the study for patients undergoing follow-up

    Contacts and Locations

    Locations

    No locations specified.

    Sponsors and Collaborators

    • Centre Hospitalier Intercommunal Creteil

    Investigators

    None specified.

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    Centre Hospitalier Intercommunal Creteil
    ClinicalTrials.gov Identifier:
    NCT04798950
    Other Study ID Numbers:
    • POLYDEB
    First Posted:
    Mar 16, 2021
    Last Update Posted:
    Nov 22, 2021
    Last Verified:
    Nov 1, 2021
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No
    Keywords provided by Centre Hospitalier Intercommunal Creteil
    bronchi dilatation
    Additional relevant MeSH terms:
    Bronchiectasis
    Kartagener Syndrome

    Study Results

    No Results Posted as of Nov 22, 2021