Bronchiectasis Effect in COPD Patients

• Sponsor: Izmir Katip Celebi University (Other)
• Overall Status: Completed
• CT.gov ID: NCT03670940
• Collaborator: (none)
• Enrollment: 35
• Actual Duration (Months): 39

Study Details

Study Description

Brief Summary

The etiology of bronchiectasis, known as permanent, abnormal, and localized development of bronchi, varies. However, most of them are responsible for infections during childhood. The prevalence of bronchiectasis is particularly high in advanced COPD patients. This phenomenon, called COPD-bronchiectasis overlap syndrome, affects the clinic of COPD patients negatively. In this study; bronchiectasis in respiratory function, exercise capacity, dyspnoea and quality of life in COPD patients.

Condition or Disease	Intervention/Treatment	Phase
Bronchiectasis; Copd

Detailed Description

The etiology of bronchiectasis, known as permanent, abnormal, and localized development of bronchi, varies. However, most of them are responsible for infections during childhood. The prevalence of bronchiectasis is particularly high in advanced COPD patients. This phenomenon, called COPD-bronchiectasis overlap syndrome, affects the clinic of COPD patients negatively. In this study; bronchiectasis in respiratory function, exercise capacity, dyspnoea and quality of life in COPD patients.

Torax CTs of patients with COPD who are admitted to the outpatient clinic will be examined. There will be two groups, group 1 in patients with COPD accompanied by bronchiectasis and group 2 in COPD patients without bronchiectasis. In both groups, respiratory function tests, exercise capacities, dyspnea perceptions and quality of life will be evaluated. The data will be compared between the two groups.

Study Design

• Study Type: Observational
• Actual Enrollment: 35 participants
• Observational Model: Cohort
• Time Perspective: Retrospective
• Official Title: Effect of Bronchiectasis on Respiratory Functions, Exercise Capacity, Dyspnea Perception and Quality of Life in COPD Patients
• Actual Study Start Date: Jan 1, 2015
• Actual Primary Completion Date: Mar 1, 2018
• Actual Study Completion Date: Apr 1, 2018

Arms and Interventions

Arm	Intervention/Treatment
COPD patients COPD patients without bronchiectasis
COPD and bronchiectasis patients COPD patients with bronchiectasis

Outcome Measures

Primary Outcome Measures

1. Exercise capacity [15 minutes]

   six minute walk test

Secondary Outcome Measures

1. Dyspnea Severity [5 minutes]

   mMRC Dyspnea Scale (0: no dyspnea, 4: very severe dyspnea)

2. Lung Function [20 minutes]

   Respiratory Function Test

3. Health Related Quality of Life [25 minutes]

   St. George Respiratory Questionnaire (maximum score: 100, lower score means better quality of life)

Eligibility Criteria

Criteria

• Ages Eligible for Study: 18 Years and Older
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Inclusion Criteria:

• above 18 years old

• clinically stable

Exclusion Criteria:

• other respiratory disease

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

• Izmir Katip Celebi University

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: Ilknur Naz, Asst. Prof., Izmir Katip Celebi University
• ClinicalTrials.gov Identifier: NCT03670940
• Other Study ID Numbers: IKC
• First Posted: Sep 14, 2018
• Last Update Posted: Sep 14, 2018
• Last Verified: Sep 1, 2018

• Individual Participant Data (IPD) Sharing Statement: No
• Plan to Share IPD: No
• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No
• Additional relevant MeSH terms: Bronchiectasis

Study Results

No Results Posted as of Sep 14, 2018