Nanofat in Post Burn Scars on the Face
Study Details
Study Description
Brief Summary
Quasi-Experimental Study: Unfiltered Nanofat Injected into Postburn Facial Scars Number of Patients: 48 Outcome Assessed on POSAS And with Imaje J Scanning Preop And Postop Statistical Comparison of Scar Done
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
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N/A |
Detailed Description
Objective: To compare the quality of post burn facial scars before and after injection of unfiltered nanofat.
Place and Duration of Study: Plastic Surgery Department, Mayo Hospital, Lahore, from January 2016 to December 2016.
Methodology: 48 patients with post burn facial scars were included, age range 4 to 32 years with Fitzpatrick skin types between 3 and 4. Patients with hypertrophic scars, contractures or keloids were excluded. Scars were assessed by a senior plastic surgeon and the patient on the POSAS. Fat was harvested from the abdomen and/or thighs with a 3 mm multi-port liposuction cannula (containing several sharp side holes of 1 mm) using Coleman's technique, emulsified, and transferred into 1 ml Leur lock syringes for injection into the subdermal or intradermal plane. Final follow up was scheduled at 6 months and scar was rated by the patient and the same surgeon on the POSAS. Pre and post op scar scores were compared and p-values calculated.
Study Design
Outcome Measures
Primary Outcome Measures
- Rejuvenation of post burn scars on the face with unfiltered nanofat injection [1 year]
Pre and post-operative POSAS score
Eligibility Criteria
Criteria
Inclusion Criteria:
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Post burn scars on the face
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Fitzpatrick skin types between 3 and 4
Exclusion Criteria:
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Hypertrophic scars
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Contractures
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Keloids
Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- King Edward Medical University
Investigators
- Principal Investigator: Saadia Jan, FRCS ed, FCPS, King Edward Medical University Lahore
Study Documents (Full-Text)
None provided.More Information
Publications
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- Neuber G. Über die Wiederanheilung vollständig vom Körper getrennter, die ganze Fettschicht enthaltender Hautstücke. Zentralblatt Chir. 1893;30:16
- Stuschke M, Budach V, Sack H. Radioresponsiveness of human glioma, sarcoma, and breast cancer spheroids depends on tumor differentiation. Int J Radiat Oncol Biol Phys. 1993 Oct 20;27(3):627-36.
- Zuk PA, Zhu M, Mizuno H, Huang J, Futrell JW, Katz AJ, Benhaim P, Lorenz HP, Hedrick MH. Multilineage cells from human adipose tissue: implications for cell-based therapies. Tissue Eng. 2001 Apr;7(2):211-28.
- 249/PLS/MHL