Music Therapy on Neutrophyl Lymphocytes Ratio, Interleukin 6 and Interleukin 10 Levels of Burnout Syndrome

• Sponsor: Indonesia University (Other)
• Overall Status: Not yet recruiting
• CT.gov ID: NCT05750160
• Collaborator: (none)
• Enrollment: 30
• Arms: 2
• Anticipated Duration (Months): 4.9

Study Details

Study Description

Brief Summary

Burnout Syndrome (BOS) can be defined as a state of stress both physically and psychically due to the burden and stressor of high work. The prevalence of BOS in health workers varies between 25-75% globally. Studies have shown that the presence of Burnout syndrome will meaningfully reduce the quality of services related to patient safety and cause immune system disorders that act as the body's defense against viral, bacterial, protozoal and fungal infections. Many strategies have been researched to help prevent and reduce the occurrence of Burnout syndrome, one of which is music therapy. The purpose of this study was to determine the effect of music therapy on the immune response in health workers with Burnout Syndrome.

This study is a randomized clinical trial with a pre and post test control group design for health workers at Dr Kariadi General Hospital and Dr. Cipto Mangunkusumo General Hospital. Subjects will be provided with information prior to the study and asked to sign an informed consent sheet if they agree to be involved in the study. Subjects will be divided into control groups and treatment groups with matching age, gender and type of work. In the treatment group, music therapy will be given as much as 3 times a week for 4 weeks. Data were taken on both groups before and after the intervention. This study used the Maslach Burnout Inventory Human Service Survey (MBI-HSS) and blood laboratory examination to determine the value of the Neutrophyl Lymphocyte Ratio, Interleukin 6 and Interleukin 10 levels.

Condition or Disease	Intervention/Treatment	Phase
Burnout Syndrome; Neutrophil-Lymphocyte Ratio; Interleukin-6; Interleukin-10	Other: music therapy	N/A

Study Design

• Study Type: Interventional
• Anticipated Enrollment: 30 participants
• Allocation: Randomized
• Intervention Model: Parallel Assignment
• Masking: None (Open Label)
• Primary Purpose: Treatment
• Official Title: The Effect of Music Therapy on Neutrophyl Lymphocytes Ratio, Interleukin 6 and Interleukin 10 Levels of Healthcare Workers With Burnout Syndrome
• Anticipated Study Start Date: Feb 1, 2023
• Anticipated Primary Completion Date: Jun 1, 2023
• Anticipated Study Completion Date: Jul 1, 2023

Arms and Interventions

Arm	Intervention/Treatment
No Intervention: Control Given education only
Experimental: Intervention Given education and music therapy	Other: music therapy; Music therapy that have been made by Music Therapist after Focus Group discussion, given three times a week for 4 weeks

Outcome Measures

Primary Outcome Measures

1. Burnout syndrome [change from baseline score at 4 weeks]

   Maslach Burnout Inventory Human Service Survey (MBI-HSS) score

2. Neutrophil Lymphocyte Ratio [Change from baseline Neutrophil Lymphocyte Ratio at 4 weeks]

   Measured with Fluorescence Flow Cytometry

3. Interleukin 6 [Change from baseline Interleukin-6 level at 4 weeks]

   Measured with Fluorescence Immunoassay

4. Interleukin 10 [Change from baseline Interleukin-10 level at 4 weeks]

   Measured with ELISA

Eligibility Criteria

Criteria

• Ages Eligible for Study: 18 Years to 60 Years
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: Yes

Inclusion Criteria:

1. Age 18 years - 60 years old

2. Health workers in the wards and polyclinic of Dr. Cipto Mangunkusumo Hospital or Dr. Kariadi Hospital, including doctors in charge of patients, nurses, residents, and other supporting health workers

3. Included in the Burnout syndrome criteria from the Maslach Burnout Inventory-Human Service Survey questionnaire

Exclusion Criteria:

1. Refusing to follow the study

2. Have a history of heart disease, kidney disease, diabetes, cancer, tuberkulosis, autoimmune, immunodeficiency

3. Taking drugs that affect the central nervous system or immunosuppressants

4. Have hearing disorder

5. Have a psychiatric disorder

6. Being pregnant

7. Healthcare workers who don't like music

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

• Indonesia University

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: Yovita Mulyakusuma, Principal Investigator, Indonesia University
• ClinicalTrials.gov Identifier: NCT05750160
• Other Study ID Numbers: KET-1362/UN2.F1/ETIK/PPM.00.02
• First Posted: Mar 1, 2023
• Last Update Posted: Mar 1, 2023
• Last Verified: Feb 1, 2023

• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No
• Additional relevant MeSH terms: Syndrome; Burnout, Psychological

Study Results

No Results Posted as of Mar 1, 2023