Comparison of Nutritional Supplements in Preventing Weight Loss in Patients With Cancer
Sponsor
Radiation Therapy Oncology Group (Other)
Overall Status
Completed
CT.gov ID
NCT00053053
Collaborator
National Cancer Institute (NCI) (NIH)
472
250
2
74.1
1.9
0
Study Details
Study Description
Brief Summary
RATIONALE: Nutritional supplements may help prevent loss of appetite, weight loss, and fatigue in patients with advanced cancer.
PURPOSE: Randomized phase III trial to compare the effectiveness of two nutritional supplements in preventing loss of appetite, weight loss, and fatigue in patients who have stage III or stage IV solid tumors.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Phase 3 |
Detailed Description
OBJECTIVES:
-
Compare the change in lean body mass of patients treated with Juven® vs a non-Juven® supplement.
-
Compare the change in fatigue and quality of life of patients treated with these supplements.
-
Compare the results of plethysmography, bioimpedance, and skinfold measurement in patients treated with these supplements.
-
Compare the weight change in patients treated with these supplements.
OUTLINE: This is a randomized, double-blind, multicenter study. Patients are stratified according to primary disease site (lung vs others), concurrent chemotherapy (yes vs no), evidence of metastases (yes vs no), and degree of weight loss (2-5% vs 6-10%). Patients are randomized to 1 of 2 treatment arms.
-
Arm I: Patients receive oral Juven® supplement twice daily for 8 weeks.
-
Arm II: Patients receive oral non-Juven® supplement twice daily for 8 weeks. All patients undergo lean body mass measurement (to include multiple body composition and weight change) and fatigue and quality of life assessments at baseline and then at 4 and 8 weeks.
PROJECTED ACCRUAL: A total of 468 patients (234 per treatment arm) will be accrued for this study within 16 months.
Study Design
Study Type:
Interventional
Actual Enrollment
:
472 participants
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Masking:
Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Primary Purpose:
Supportive Care
Official Title:
A Double-Blind Study Of Nutritional Intervention For The Treatment Of Cancer Cachexia Using Juven® Nutritional Supplement
Study Start Date
:
Dec 1, 2002
Actual Primary Completion Date
:
Mar 1, 2005
Actual Study Completion Date
:
Feb 1, 2009
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Experimental: Juven supplement Juven nutritional supplement given twice a day for 8 weeks |
Dietary Supplement: Juven
|
| Active Comparator: Non-Juven supplement Non-Juven nutritional supplement given twice a day for 8 weeks |
Dietary Supplement: Non-Juven Supplement
|
Outcome Measures
Primary Outcome Measures
- Lean body mass [Study entry to 8 weeks]
Secondary Outcome Measures
- Fatigue [Study entry to 8 weeks]
- Quality of Life [Study entry to 8 weeks]
- Body weight [Study entry to 8 weeks]
- Correlation between change in lean body mass and body plethysmography, bioimpedance and skin-fold measurement [Study entry to 8 weeks]
Eligibility Criteria
Criteria
Ages Eligible for Study:
17 Years
to 120 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
DISEASE CHARACTERISTICS:
-
Histologically or cytologically confirmed solid tumor or lymphoma with no leukemic aspect
-
Stage III or IV or any other stage associated with current metastatic disease at presentation
-
No primary or metastatic brain tumors
-
Weight loss of at least 2% but no more than 10% within the past 3 months
-
No ascites
PATIENT CHARACTERISTICS:
Age
- 17 and over
Performance status
- Zubrod 0-2
Life expectancy
- At least 3 months
Hematopoietic
- Not specified
Hepatic
- Not specified
Renal
- No hypercalcemia
Cardiovascular
-
No persistent moderate or severe peripheral edema
-
No uncontrolled congestive heart failure
Gastrointestinal
-
No enteric fistula
-
No concurrent intestinal obstruction
-
Prior intestinal obstruction allowed
Other
-
Not pregnant or nursing
-
Negative pregnancy test
-
No uncontrolled infections
-
No other serious medical illness
-
No metabolic disorder
PRIOR CONCURRENT THERAPY:
Biologic therapy
- Not specified
Chemotherapy
- Concurrent chemotherapy allowed
Endocrine therapy
-
No dexamethasone as an appetite stimulant
-
Intermittent dexamethasone during concurrent chemotherapy allowed
Radiotherapy
- Concurrent radiotherapy allowed
Surgery
-
At least 1 week since prior minor surgery
-
At least 3 weeks since prior major surgery
Other
-
At least 30 days since prior total parenteral nutrition
-
No concurrent parenteral feedings
-
No concurrent known appetite stimulants (e.g., megestrol or dronabinol)
-
No concurrent omega 3 fatty acids or their congeners (e.g., ProSure™)
-
No concurrent amino acid supplements
-
Concurrent use of other dietary supplements (e.g., Ensure® or Boost) is allowed
-
Concurrent enteral feedings via PEG or nasogastric tube are allowed
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Comprehensive Cancer Center at University of Alabama at Birmingham | Birmingham | Alabama | United States | 35294-3300 |
| 2 | Comprehensive Cancer Institute | Huntsville | Alabama | United States | 35801 |
| 3 | MBCCOP - Gulf Coast | Mobile | Alabama | United States | 36607 |
| 4 | Montgomery Cancer Center | Montgomery | Alabama | United States | 36106-3657 |
| 5 | DCH Cancer Treatment Center | Tuscaloosa | Alabama | United States | 35401 |
| 6 | Foundation for Cancer Research and Education | Phoenix | Arizona | United States | 85013 |
| 7 | Providence Saint Joseph Medical Center - Burbank | Burbank | California | United States | 91505 |
| 8 | Mount Diablo Regional Cancer Center | Concord | California | United States | 94524-4110 |
| 9 | City of Hope Comprehensive Cancer Center | Duarte | California | United States | 91010-3000 |
| 10 | California Cancer Center - Woodward Park Office | Fresno | California | United States | 93720 |
| 11 | Saint Agnes Cancer Center | Fresno | California | United States | 93720 |
| 12 | Sutter Health Western Division Cancer Research Group | Greenbrae | California | United States | 94904 |
| 13 | Loma Linda University Cancer Institute at Loma Linda University Medical Center | Loma Linda | California | United States | 92354 |
| 14 | Veterans Affairs Medical Center - Long Beach | Long Beach | California | United States | 90822 |
| 15 | USC/Norris Comprehensive Cancer Center and Hospital | Los Angeles | California | United States | 90033-0804 |
| 16 | Jonsson Comprehensive Cancer Center at UCLA | Los Angeles | California | United States | 90095-1714 |
| 17 | CCOP - Bay Area Tumor Institute | Oakland | California | United States | 94609-3305 |
| 18 | Huntington Cancer Center at Huntington Hospital | Pasadena | California | United States | 91105 |
| 19 | Robert and Beverly Lewis Family Cancer Care Center at Pomona Valley Hospital Medical Center | Pomona | California | United States | 91767 |
| 20 | Radiation Oncology Centers - Sacramento | Sacramento | California | United States | 95815 |
| 21 | Radiation Medical Group, Incorporated | San Diego | California | United States | 92101-1492 |
| 22 | Naval Medical Center - San Diego | San Diego | California | United States | 92134-3202 |
| 23 | UCSF Comprehensive Cancer Center | San Francisco | California | United States | 94115 |
| 24 | O'Connor Hospital | San Jose | California | United States | 95128 |
| 25 | CCOP - Santa Rosa Memorial Hospital | Santa Rosa | California | United States | 95403 |
| 26 | St. Joseph's Regional Cancer Center | Stockton | California | United States | 95204 |
| 27 | Torrance Memorial Medical Center | Torrance | California | United States | 90505 |
| 28 | General Robert Huyser Cancer Center at David Grant Medical Center | Travis Air Force Base | California | United States | 94535 |
| 29 | Memorial Hospital Cancer Center | Colorado Springs | Colorado | United States | 80909 |
| 30 | University of Colorado Cancer Center at University of Colorado Health Sciences Center | Denver | Colorado | United States | 80010 |
| 31 | St. Mary's Regional Cancer Center at St. Mary's Hospital and Medical Center | Grand Junction | Colorado | United States | 81502-1628 |
| 32 | Hospital of Saint Raphael | New Haven | Connecticut | United States | 06511 |
| 33 | Yale Comprehensive Cancer Center | New Haven | Connecticut | United States | 06520-8040 |
| 34 | CCOP - Christiana Care Health Services | Newark | Delaware | United States | 19713 |
| 35 | Sibley Memorial Hospital | Washington | District of Columbia | United States | 20016 |
| 36 | 21st Century Oncology - Fort Myers | Fort Myers | Florida | United States | 33901-8082 |
| 37 | University of Florida Shands Cancer Center | Gainesville | Florida | United States | 32610-0385 |
| 38 | Florida Radiation Oncology Group | Jacksonville | Florida | United States | 32207 |
| 39 | Holmes Regional Medical Center | Melbourne | Florida | United States | 32901-3276 |
| 40 | CCOP - Mount Sinai Medical Center | Miami Beach | Florida | United States | 33140 |
| 41 | University of Miami Sylvester Comprehensive Cancer Center | Miami | Florida | United States | 33136 |
| 42 | Baptist-South Miami Regional Cancer Program | Miami | Florida | United States | 33176-2197 |
| 43 | Bay Medical Center | Panama City | Florida | United States | 32401 |
| 44 | Gulf Coast Cancer Treatment Center | Panama City | Florida | United States | 32405-4587 |
| 45 | Sarasota Radiation and Medical Oncology Center | Sarasota | Florida | United States | 34233 |
| 46 | Tallahassee Memorial Hospital | Tallahassee | Florida | United States | 32308 |
| 47 | H. Lee Moffitt Cancer Center and Research Institute at University of South Florida | Tampa | Florida | United States | 33612-9497 |
| 48 | Winship Cancer Institute of Emory University | Atlanta | Georgia | United States | 30322 |
| 49 | CCOP - Atlanta Regional | Atlanta | Georgia | United States | 30342-1701 |
| 50 | John B. Amos Community Cancer Center | Columbus | Georgia | United States | 31904 |
| 51 | Regional Radiation Oncology Center at Rome | Rome | Georgia | United States | 30165 |
| 52 | MBCCOP - Hawaii | Honolulu | Hawaii | United States | 96813 |
| 53 | Northwest Community Hospital | Arlington Heights | Illinois | United States | 60005 |
| 54 | Robert H. Lurie Comprehensive Cancer Center at Northwestern University | Chicago | Illinois | United States | 60611-3013 |
| 55 | CCOP - Central Illinois | Decatur | Illinois | United States | 62526 |
| 56 | Ingalls Cancer Care Center at Ingalls Memorial Hospital | Harvey | Illinois | United States | 60426 |
| 57 | Cardinal Bernardin Cancer Center at Loyola University Medical Center | Maywood | Illinois | United States | 60153 |
| 58 | Lutheran General Cancer Care Center | Park Ridge | Illinois | United States | 60068 |
| 59 | Methodist Medical Center of Illinois | Peoria | Illinois | United States | 61636 |
| 60 | St. John's Cancer Center at St. John's Medical Center | Anderson | Indiana | United States | 46016 |
| 61 | Bloomington Hospital | Bloomington | Indiana | United States | 47402 |
| 62 | Veterans Affairs Medical Center - Indianapolis (Roudebush) | Indianapolis | Indiana | United States | 46202 |
| 63 | Methodist Cancer Center at Methodist Hospital | Indianapolis | Indiana | United States | 46206-1367 |
| 64 | Oncology Institute of Greater Lafayette | Lafayette | Indiana | United States | 47904 |
| 65 | Cancer Center at Ball Memorial Hospital | Muncie | Indiana | United States | 47303-3499 |
| 66 | CCOP - Northern Indiana CR Consortium | South Bend | Indiana | United States | 46601 |
| 67 | Wendt Regional Cancer Center at Finley Hospital | Dubuque | Iowa | United States | 52001 |
| 68 | Esther Marie Hatton Cancer Care Center at St. Elizabeth Medical Center | Edgewood | Kentucky | United States | 41017 |
| 69 | Central Baptist Hospital | Lexington | Kentucky | United States | 40503 |
| 70 | Cancer Center at Lexington Clinic | Lexington | Kentucky | United States | 40504 |
| 71 | Markey Cancer Center at University of Kentucky Chandler Medical Center | Lexington | Kentucky | United States | 40536-0293 |
| 72 | James Graham Brown Cancer Center at University of Louisville | Louisville | Kentucky | United States | 40202 |
| 73 | Louisville Radiation Oncology Center at Caritas Regional Cancer Center | Louisville | Kentucky | United States | 40215 |
| 74 | Merle M. Mahr Cancer Center at Regional Medical Center of Hopkins County | Madisonville | Kentucky | United States | 42431 |
| 75 | Mary Bird Perkins Cancer Center - Baton Rouge | Baton Rouge | Louisiana | United States | 70809-3482 |
| 76 | Tulane Cancer Center at Tulane University Hospital and Clinic | New Orleans | Louisiana | United States | 70112-2699 |
| 77 | MBCCOP - LSU Health Sciences Center | New Orleans | Louisiana | United States | 70112 |
| 78 | CCOP - Ochsner | New Orleans | Louisiana | United States | 70121 |
| 79 | Maine Medical Center - Bramhall Campus | Portland | Maine | United States | 04102 |
| 80 | DeCesaris Cancer Institute at Anne Arundel Medical Center | Annapolis | Maryland | United States | 21401 |
| 81 | Greenebaum Cancer Center at University of Maryland Medical Center | Baltimore | Maryland | United States | 21201 |
| 82 | Cancer Center at Greater Baltimore Medical Center | Baltimore | Maryland | United States | 21204 |
| 83 | Harbor Hospital Center | Baltimore | Maryland | United States | 21215-1290 |
| 84 | Alvin and Lois Lapidus Cancer Institute at Sinai Hospital | Baltimore | Maryland | United States | 21215 |
| 85 | St. Agnes Cancer Center | Baltimore | Maryland | United States | 21229 |
| 86 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Baltimore | Maryland | United States | 21231-2410 |
| 87 | Peninsula Regional Medical Center | Salisbury | Maryland | United States | 21801 |
| 88 | Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute | Boston | Massachusetts | United States | 02114 |
| 89 | Cancer Research Center at Boston Medical Center | Boston | Massachusetts | United States | 02118 |
| 90 | Cape Cod Hospital | Hyannis | Massachusetts | United States | 02601 |
| 91 | Veterans Affairs Medical Center - Boston (Jamaica Plain) | Jamaica Plain | Massachusetts | United States | 02130 |
| 92 | NSMC Cancer Center - Peabody | Peabody | Massachusetts | United States | 01960 |
| 93 | CCOP - Michigan Cancer Research Consortium | Ann Arbor | Michigan | United States | 48106 |
| 94 | University of Michigan Comprehensive Cancer Center | Ann Arbor | Michigan | United States | 48109-0010 |
| 95 | Barbara Ann Karmanos Cancer Institute | Detroit | Michigan | United States | 48201 |
| 96 | Josephine Ford Cancer Center at Henry Ford Health System | Detroit | Michigan | United States | 48202 |
| 97 | Great Lakes Cancer Institute at McLaren Regional Medical Center | Flint | Michigan | United States | 48532-3685 |
| 98 | CCOP - Kalamazoo | Kalamazoo | Michigan | United States | 49007-3731 |
| 99 | Upper Michigan Cancer Center at Marquette General Hospital | Marquette | Michigan | United States | 49855 |
| 100 | MidMichigan Medical Center - Midland | Midland | Michigan | United States | 48670 |
| 101 | CCOP - Beaumont | Royal Oak | Michigan | United States | 48073-6769 |
| 102 | William Beaumont Hospital - Royal Oak Campus | Royal Oak | Michigan | United States | 48073 |
| 103 | William Beaumont Hospital - Troy Campus | Troy | Michigan | United States | 48085 |
| 104 | Fairview University Medical Center - University Campus | Minneapolis | Minnesota | United States | 55455 |
| 105 | Mayo Clinic Cancer Center | Rochester | Minnesota | United States | 55905-0001 |
| 106 | CCOP - Metro-Minnesota | Saint Louis Park | Minnesota | United States | 55416 |
| 107 | Ellis Fischel Cancer Center at University of Missouri - Columbia | Columbia | Missouri | United States | 65203 |
| 108 | CCOP - Kansas City | Kansas City | Missouri | United States | 64131 |
| 109 | Saint Louis University Cancer Center | Saint Louis | Missouri | United States | 63110-0250 |
| 110 | CCOP - Cancer Research for the Ozarks | Springfield | Missouri | United States | 65807 |
| 111 | Siteman Cancer Center at Barnes-Jewish Hospital | St. Louis | Missouri | United States | 63110 |
| 112 | CCOP - Montana Cancer Consortium | Billings | Montana | United States | 59101 |
| 113 | CCOP - Missouri Valley Cancer Consortium | Omaha | Nebraska | United States | 68106 |
| 114 | Methodist Hospital Cancer Center at Nebraska Methodist Hospital - Omaha | Omaha | Nebraska | United States | 68114-4199 |
| 115 | UNMC Eppley Cancer Center at the University of Nebraska Medical Center | Omaha | Nebraska | United States | 68198-7521 |
| 116 | CCOP - Southern Nevada Cancer Research Foundation | Las Vegas | Nevada | United States | 89106 |
| 117 | Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center | Lebanon | New Hampshire | United States | 03756-0002 |
| 118 | Elliot Regional Cancer Center | Manchester | New Hampshire | United States | 03103 |
| 119 | Veterans Affairs Medical Center - East Orange | East Orange | New Jersey | United States | 07018 |
| 120 | John F. Kennedy Medical Center | Edison | New Jersey | United States | 08818 |
| 121 | Monmouth Medical Center | Long Branch | New Jersey | United States | 07740-6395 |
| 122 | Fox Chase Virtua Health Cancer Program - Marlton | Mount Holly | New Jersey | United States | 08060 |
| 123 | Cancer Institute of New Jersey at UMDNJ - Robert Wood Johnson Medical School | New Brunswick | New Jersey | United States | 08903 |
| 124 | Newark Beth Israel Medical Center | Newark | New Jersey | United States | 07112 |
| 125 | Atlantic City Medical Center - Mainland Division | Pomona | New Jersey | United States | 08240 |
| 126 | University Medical Center at Princeton | Princeton | New Jersey | United States | 08540 |
| 127 | Valley Hospital - Ridgewood | Ridgewood | New Jersey | United States | 07450 |
| 128 | Community Medical Center | Toms River | New Jersey | United States | 08755 |
| 129 | Fox Chase Cancer Center at St. Francis Medical Center | Trenton | New Jersey | United States | 08629 |
| 130 | South Jersey Healthcare Regional Cancer Center | Vineland | New Jersey | United States | 08360 |
| 131 | Associated Radiologists, P.A. at Warren Radiation Therapy Center | Warren | New Jersey | United States | 07059 |
| 132 | Radiation Oncology Associates, PA | Albuquerque | New Mexico | United States | 87109 |
| 133 | Lourdes Regional Cancer Center | Binghamton | New York | United States | 13905 |
| 134 | SUNY Downstate Medical Center | Brooklyn | New York | United States | 11203 |
| 135 | New York Methodist Hospital | Brooklyn | New York | United States | 11215-3609 |
| 136 | Finger Lakes Radiation Oncology Center at Clifton Springs Hospital and clinic | Clifton Springs | New York | United States | 14432 |
| 137 | CCOP - Syracuse Hematology-Oncology Associates of Central New York, P.C. | East Syracuse | New York | United States | 13057 |
| 138 | CCOP - North Shore University Hospital | Manhasset | New York | United States | 11030 |
| 139 | Beth Israel Medical Center - Philipps Ambulatory Care Center | New York | New York | United States | 10003 |
| 140 | Memorial Sloan-Kettering Cancer Center | New York | New York | United States | 10021 |
| 141 | Herbert Irving Comprehensive Cancer Center at Columbia University | New York | New York | United States | 10032 |
| 142 | Fitzpatrick Cancer Center at Champlain Valley Physicians Hospital Medical Center | Plattsburgh | New York | United States | 12901-1490 |
| 143 | James P. Wilmot Cancer Center at University of Rochester Medical Center | Rochester | New York | United States | 14642 |
| 144 | North Shore Radiation Oncology | Setauket | New York | United States | 11733 |
| 145 | SUNY Upstate Medical University Hospital | Syracuse | New York | United States | 13210 |
| 146 | Riverhill Radiation Oncology | Yonkers | New York | United States | 10701 |
| 147 | Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill | Chapel Hill | North Carolina | United States | 27599-7295 |
| 148 | Batte Cancer Center at Northeast Medical Center | Concord | North Carolina | United States | 28025 |
| 149 | CCOP - Southeast Cancer Control Consortium | Goldsboro | North Carolina | United States | 27534-9479 |
| 150 | Leo W. Jenkins Cancer Center at Pitt County Memorial Hospital | Greenville | North Carolina | United States | 27835-6028 |
| 151 | Comprehensive Cancer Center at Wake Forest University | Winston-Salem | North Carolina | United States | 27157-1096 |
| 152 | Trinity Cancer Care Center | Minot | North Dakota | United States | 58701 |
| 153 | McDowell Cancer Center at Akron General Medical Center | Akron | Ohio | United States | 44302 |
| 154 | Akron City Hospital at Summa Health System | Akron | Ohio | United States | 44304 |
| 155 | Cancer Center at Christ Hospital | Cincinnati | Ohio | United States | 45219 |
| 156 | Charles M. Barrett Cancer Center at University Hospital | Cincinnati | Ohio | United States | 45219 |
| 157 | Ireland Cancer Center at University Hospitals of Cleveland and Case Western Reserve University | Cleveland | Ohio | United States | 44106-5047 |
| 158 | Cleveland Clinic Taussig Cancer Center | Cleveland | Ohio | United States | 44195 |
| 159 | CCOP - Columbus | Columbus | Ohio | United States | 43206 |
| 160 | Arthur G. James Cancer Hospital and Solove Research Institute at Ohio State University | Columbus | Ohio | United States | 43210-1240 |
| 161 | CCOP - Dayton | Dayton | Ohio | United States | 45429 |
| 162 | Parma Community General Hospital | Parma | Ohio | United States | 44129 |
| 163 | CCOP - Toledo Community Hospital | Toledo | Ohio | United States | 43623-3456 |
| 164 | Frank C. Love Cancer Institute at St. Anthony Hospital | Oklahoma City | Oklahoma | United States | 73102 |
| 165 | Oklahoma University Medical Center | Oklahoma City | Oklahoma | United States | 73104 |
| 166 | LaFortune Cancer Center at St. John Health System | Tulsa | Oklahoma | United States | 74104 |
| 167 | CCOP - Oklahoma | Tulsa | Oklahoma | United States | 74136 |
| 168 | CCOP - Columbia River Oncology Program | Portland | Oregon | United States | 97225 |
| 169 | Abington Memorial Hospital | Abington | Pennsylvania | United States | 19001 |
| 170 | John and Dorothy Morgan Cancer Center at Lehigh Valley Hospital | Allentown | Pennsylvania | United States | 18105-1556 |
| 171 | St. Luke's Hospital Cancer Center | Bethlehem | Pennsylvania | United States | 18015 |
| 172 | Geisinger Medical Center | Danville | Pennsylvania | United States | 17822-2001 |
| 173 | Mercy Fitzgerald Hospital | Darby | Pennsylvania | United States | 19023 |
| 174 | Delaware County Regional Cancer Center at Delaware County Memorial Hospital | Drexel Hill | Pennsylvania | United States | 19026 |
| 175 | Dale and Frances Hughes Cancer Center at Pocono Medical Center | East Stroudsburg | Pennsylvania | United States | 18301 |
| 176 | Penn State Cancer Institute at Milton S. Hershey Medical Center | Hershey | Pennsylvania | United States | 17033 |
| 177 | Abramson Cancer Center of the University of Pennsylvania | Philadelphia | Pennsylvania | United States | 19104-4283 |
| 178 | Kimmel Cancer Center at Thomas Jefferson University - Philadelphia | Philadelphia | Pennsylvania | United States | 19107-5541 |
| 179 | Fox Chase Cancer Center | Philadelphia | Pennsylvania | United States | 19111 |
| 180 | Albert Einstein Cancer Center | Philadelphia | Pennsylvania | United States | 19141-3098 |
| 181 | Allegheny Cancer Center at Allegheny General Hospital | Pittsburgh | Pennsylvania | United States | 15212-4772 |
| 182 | Mercy Hospital of Pittsburgh | Pittsburgh | Pennsylvania | United States | 15219 |
| 183 | Western Pennsylvania Cancer Institute at Western Pennsylvania Hospital | Pittsburgh | Pennsylvania | United States | 15224 |
| 184 | Hillman Cancer Center at University of Pittsburgh Cancer Institute | Pittsburgh | Pennsylvania | United States | 15232 |
| 185 | Reading Hospital and Medical Center | Reading | Pennsylvania | United States | 19612-6052 |
| 186 | Mercy Hospital Cancer Center - Scranton | Scranton | Pennsylvania | United States | 18501 |
| 187 | Wilkes-Barre General Hospital | Wilkes-Barre | Pennsylvania | United States | 18764-0001 |
| 188 | CCOP - MainLine Health | Wynnewood | Pennsylvania | United States | 19096 |
| 189 | York Cancer Center at Wellspan Health | York | Pennsylvania | United States | 17403 |
| 190 | Roger Williams Medical Center | Providence | Rhode Island | United States | 02908-4735 |
| 191 | CCOP - Greenville | Greenville | South Carolina | United States | 29615 |
| 192 | CCOP - Upstate Carolina | Spartanburg | South Carolina | United States | 29303 |
| 193 | Rapid City Regional Hospital | Rapid City | South Dakota | United States | 57709 |
| 194 | West Tennessee Cancer Center at Jackson-Madison County General Hospital | Jackson | Tennessee | United States | 38301 |
| 195 | Vanderbilt-Ingram Cancer Center at Vanderbilt Medical Center | Nashville | Tennessee | United States | 37232-5671 |
| 196 | Harrington Cancer Center | Amarillo | Texas | United States | 79106 |
| 197 | Arlington Cancer Center - Arlington | Arlington | Texas | United States | 76012 |
| 198 | University of Texas Medical Branch | Galveston | Texas | United States | 77555-0209 |
| 199 | M.D. Anderson Cancer Center at University of Texas | Houston | Texas | United States | 77030-4009 |
| 200 | Wilford Hall Medical Center | Lackland Air Force Base | Texas | United States | 78236-5300 |
| 201 | Joe Arrington Cancer Research and Treatment Center | Lubbock | Texas | United States | 79410 |
| 202 | University of Texas Health Science Center at San Antonio | San Antonio | Texas | United States | 78284-7811 |
| 203 | CCOP - Scott and White Hospital | Temple | Texas | United States | 76508 |
| 204 | Utah Valley Regional Medical Center - Provo | Provo | Utah | United States | 84604 |
| 205 | Dixie Regional Medical Center | Saint George | Utah | United States | 84770 |
| 206 | University of Utah Health Sciences Center | Salt Lake City | Utah | United States | 84132 |
| 207 | LDS Hospital | Salt Lake City | Utah | United States | 84143 |
| 208 | Vermont Cancer Center at University of Vermont | Burlington | Vermont | United States | 05405-0075 |
| 209 | Community Cancer Center at Rutland Regional Medical Center | Rutland | Vermont | United States | 05701 |
| 210 | Cancer Center at the University of Virginia | Charlottesville | Virginia | United States | 22908 |
| 211 | RMH Regional Cancer Center | Harrisonburg | Virginia | United States | 22801 |
| 212 | Naval Medical Center - Portsmouth | Portsmouth | Virginia | United States | 23708-1912 |
| 213 | Bon Secours Cancer Care at St. Mary's Hospital | Richmond | Virginia | United States | 23226 |
| 214 | Massey Cancer Center at Virginia Commonwealth University | Richmond | Virginia | United States | 23298-0058 |
| 215 | Cancer Institute at Virginia Mason Medical Center | Seattle | Washington | United States | 98111 |
| 216 | Deaconess Medical Center | Spokane | Washington | United States | 99204 |
| 217 | Yakima Valley Memorial Hospital | Yakima | Washington | United States | 98902 |
| 218 | Schiffler Cancer Center at Wheeling Hospital | Wheeling | West Virginia | United States | 26003 |
| 219 | CCOP - St. Vincent Hospital Cancer Center, Green Bay | Green Bay | Wisconsin | United States | 54301 |
| 220 | St. Vincent Hospital | Green Bay | Wisconsin | United States | 54307-3508 |
| 221 | Gundersen Lutheran Cancer Center at Gundersen Lutheran Medical Center | La Crosse | Wisconsin | United States | 54601 |
| 222 | University of Wisconsin Comprehensive Cancer Center | Madison | Wisconsin | United States | 53792 |
| 223 | CCOP - Marshfield Clinic Research Foundation | Marshfield | Wisconsin | United States | 54449 |
| 224 | Marshfield Clinic - Marshfield Center | Marshfield | Wisconsin | United States | 54449 |
| 225 | Community Memorial Hospital | Menomonee Falls | Wisconsin | United States | 53051 |
| 226 | Columbia St. Mary's - Columbia Campus | Milwaukee | Wisconsin | United States | 53211 |
| 227 | Vince Lombardi Cancer Clinic at St. Luke's Medical Center | Milwaukee | Wisconsin | United States | 53215 |
| 228 | Veterans Affairs Medical Center - Milwaukee (Zablocki) | Milwaukee | Wisconsin | United States | 53295 |
| 229 | All Saints Cancer Center at All Saints Healthcare | Racine | Wisconsin | United States | 53405 |
| 230 | Waukesha Memorial Hospital Regional Cancer Center | Waukesha | Wisconsin | United States | 53188 |
| 231 | Tom Baker Cancer Centre - Calgary | Calgary | Alberta | Canada | T2N 4N2 |
| 232 | Cross Cancer Institute | Edmonton | Alberta | Canada | T6G 1Z2 |
| 233 | Doctor Leon Richard Oncology Centre | Moncton | New Brunswick | Canada | E1C 8X3 |
| 234 | Saint John Regional Hospital | Saint John | New Brunswick | Canada | E2L 4L2 |
| 235 | Newfoundland Cancer Treatment and Research Foundation | St. Johns | Newfoundland and Labrador | Canada | A1B 3V6 |
| 236 | Nova Scotia Cancer Centre at Queen Elizabeth II Health Sciences Centre | Halifax | Nova Scotia | Canada | B3H 1V7 |
| 237 | Margaret and Charles Juravinski Cancer Centre | Hamilton | Ontario | Canada | L8V 5C2 |
| 238 | Cancer Centre of Southeastern Ontario | Kingston | Ontario | Canada | K7L 5P9 |
| 239 | London Regional Cancer Program at London Health Sciences Centre | London | Ontario | Canada | N6A 4L6 |
| 240 | Ottawa Hospital Regional Cancer Centre - General Campus | Ottawa | Ontario | Canada | K1H 8L6 |
| 241 | Northeastern Ontario Regional Cancer Centre | Sudbury | Ontario | Canada | P3E 5J1 |
| 242 | Regional Cancer Care at Thunder Bay Regional Health Sciences Centre | Thunder Bay | Ontario | Canada | P7B 6V4 |
| 243 | Toronto Sunnybrook Regional Cancer Centre | Toronto | Ontario | Canada | M4N 3M5 |
| 244 | Princess Margaret Hospital | Toronto | Ontario | Canada | M5G 2M9 |
| 245 | Centre Hospitalier de l'Universite de Montreal | Montreal | Quebec | Canada | H2L 4MI |
| 246 | McGill Cancer Centre at McGill University | Montreal | Quebec | Canada | H2W 1S6 |
| 247 | Centre Hospitalier Universitaire de Quebec | Quebec City | Quebec | Canada | G1R 2J6 |
| 248 | CHUS-Hopital Fleurimont | Sherbrooke | Quebec | Canada | J1H 5N4 |
| 249 | Allan Blair Cancer Centre at Pasqua Hospital | Regina | Saskatchewan | Canada | S4T 7T1 |
| 250 | Saskatoon Cancer Centre | Saskatoon | Saskatchewan | Canada | S7N 4H4 |
Sponsors and Collaborators
- Radiation Therapy Oncology Group
- National Cancer Institute (NCI)
Investigators
- Study Chair: Lawrence B. Berk, MD, PhD, CCOP - Columbus
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.Responsible Party:
Radiation Therapy Oncology Group
ClinicalTrials.gov Identifier:
NCT00053053
Other Study ID Numbers:
- RTOG-0122
- CDR0000269100
First Posted:
Jan 28, 2003
Last Update Posted:
Dec 8, 2016
Last Verified:
Oct 1, 2013
Keywords provided by Radiation Therapy Oncology Group
Additional relevant MeSH terms: