Calcium Levels in Major Trauma
Sponsor
Hossam Abdel Rahman Ahmed Ismail (Other)
Overall Status
Not yet recruiting
CT.gov ID
NCT06103292
Collaborator
(none)
150
21
Study Details
Study Description
Brief Summary
To assess and treat The calcium level abnormalities in major trauma pre and post receiving blood transfusions .
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Detailed Description
Primary objective:
- to evaluate the level of ionized calcium in multiple trauma patients with massive hemorrhage
Secondary objective:
- to build a relation between the level of ionized calcium and the degree of hemorrhagic shock
Study Design
Study Type:
Observational
Anticipated Enrollment
:
150 participants
Observational Model:
Cohort
Time Perspective:
Prospective
Official Title:
Ionized Calcium Level Abnormalities In Major Trauma Patients Pre And Post Receiving Blood Transfusion And Its Relation To Mortality Rate
Anticipated Study Start Date
:
Mar 1, 2024
Anticipated Primary Completion Date
:
Sep 1, 2025
Anticipated Study Completion Date
:
Dec 1, 2025
Outcome Measures
Primary Outcome Measures
- follow up ionized calcium level [24 hrs]
Eligibility Criteria
Criteria
Ages Eligible for Study:
18 Years
to 70 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:
-
18 years old - < 70 years
-
Major trauma patients.
-
Admission and Ionized calcium measurement before blood transfusions
Exclusion Criteria:
-
patients below 18 years or > 70 years of age.
-
Pregnant women
-
Arrested patients
-
Patients managed outside the hospital and had received blood transfusions
Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- Hossam Abdel Rahman Ahmed Ismail
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
- Barry GD. Plasma calcium concentration changes in hemorrhagic shock. Am J Physiol. 1971 Apr;220(4):874-9. doi: 10.1152/ajplegacy.1971.220.4.874. No abstract available.
- Heckbert SR, Vedder NB, Hoffman W, Winn RK, Hudson LD, Jurkovich GJ, Copass MK, Harlan JM, Rice CL, Maier RV. Outcome after hemorrhagic shock in trauma patients. J Trauma. 1998 Sep;45(3):545-9. doi: 10.1097/00005373-199809000-00022.
- Sauaia A, Moore FA, Moore EE, Moser KS, Brennan R, Read RA, Pons PT. Epidemiology of trauma deaths: a reassessment. J Trauma. 1995 Feb;38(2):185-93. doi: 10.1097/00005373-199502000-00006.
- Zink KA, Sambasivan CN, Holcomb JB, Chisholm G, Schreiber MA. A high ratio of plasma and platelets to packed red blood cells in the first 6 hours of massive transfusion improves outcomes in a large multicenter study. Am J Surg. 2009 May;197(5):565-70; discussion 570. doi: 10.1016/j.amjsurg.2008.12.014.
Responsible Party:
Hossam Abdel Rahman Ahmed Ismail,
Hossam Ismail,
Assiut University
ClinicalTrials.gov Identifier:
NCT06103292
Other Study ID Numbers:
- Calcium abnormaities in trauma
First Posted:
Oct 26, 2023
Last Update Posted:
Oct 26, 2023
Last Verified:
Oct 1, 2023
Individual Participant Data (IPD) Sharing Statement:
No
Plan to Share IPD:
No
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms: