Role of Routine Nasogastric Decompression After Subtotal Gastrectomy

• Sponsor: Chinese University of Hong Kong (Other)
• Overall Status: Unknown status
• CT.gov ID: NCT00164918
• Collaborator: (none)
• Enrollment: 90
• Location: 1

Study Details

Study Description

Brief Summary

The aim of the study is to evaluate whether subtotal gastrectomy without post-operative nasogastric decompression is better in terms of early post-operative bowel function and chest complication.

Condition or Disease	Intervention/Treatment	Phase
Cancer of Stomach	Device: nasogastric tube	Phase 3

Detailed Description

Nasogastric decompression is an intra-operative routine in most of the time to facilitate exposure of operative field during elective subtotal gastrectomy, but whether it should be retained post-operatively is controversial. Nasogastric decompression helps to drain the gastric remnant in case there is edema around the gastrojejunostomy, ileus and delayed gastric emptying, which can theoretically relieve nausea and abdominal distension. Besides, it may help decrease diaphragmatic splintage and hence decrease chance of chest infection if ileus occurs. However, nasogastric intubation could cause patient discomfort; also it has been shown that it would cause gastroesophageal reflux which may be associated with chest complication. There have been studies showing that routine post-operative nasogastric decompression is not necessary for gastrectomy in general, but the role in subtotal gastrectomy for stomach cancer is not well defined.

Study Design

• Study Type: Interventional
• Allocation: Randomized
• Intervention Model: Parallel Assignment
• Masking: None (Open Label)
• Primary Purpose: Treatment
• Official Title: Role of Routine Nasogastric Decompression After Subtotal Gastrectomy
• Study Start Date: Sep 1, 2004

Outcome Measures

Primary Outcome Measures

1. Bowel function and related symptoms early post-op []

Eligibility Criteria

Criteria

• Ages Eligible for Study: 18 Weeks and Older
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Inclusion Criteria:All patients suffering from carcinoma of stomach, decided for operation

• subtotal, D1/D2 dissection

• palliative resection

Exclusion Criteria:

• actively bleeding tumor

• perforation of tumor

• patient present with gastric outlet obstruction

• combine organ excision

• known diabetes with nephropathy

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Surgical Ward, Prince of Wales Hospital	Hong Kong		China

Sponsors and Collaborators

• Chinese University of Hong Kong

Investigators

• Principal Investigator: Enders K.W. Ng, MD, Chinese University of Hong Kong

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• ClinicalTrials.gov Identifier: NCT00164918
• Other Study ID Numbers: CRE-2004.311
• First Posted: Sep 14, 2005
• Last Update Posted: Sep 14, 2005
• Last Verified: Sep 1, 2005

• Additional relevant MeSH terms: Stomach Neoplasms

Study Results

No Results Posted as of Sep 14, 2005