Clincosm LogoSign in Get a demo

Effect of Aerobic or Resistance Exercise on the Endothelial Response in Post-acute Myocardial Infarction Patients Submitted to Angioplasty

Sponsor
Instituto de Cardiologia do Rio Grande do Sul (Other)
Overall Status
Completed
CT.gov ID
NCT04000893
Collaborator
(none)
20
Enrollment
1
Location
2
Arms
10.8
Actual Duration (Months)
1.9
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Cardiac Rehabilitation, as art and acting science multiprofessional, is based on the training with exercises that provides the post-infarct patients to satisfactorily re-establish the patient's clinical condition and that improve the functional capacity of these individuals.

Evidence shows that aerobic exercise training provides improvements in the endothelial function of this population. However, we do not yet have strong evidence of other modalities of exercise in these parameters in post-infarction patients treated with angioplasty.

Condition or Disease Intervention/Treatment Phase
  • Other: Resistance exercise session
 N/A

Study Design

Study Type:
Interventional
Actual Enrollment :
20 participants
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Masking:
Single (Outcomes Assessor)
Primary Purpose:
Supportive Care
Official Title:
Effect of Aerobic or Resistance Exercise on the Endothelial Response in Post-acute Myocardial Infarction Patients Submitted to Angioplasty: Randomized Clinical Trial
Actual Study Start Date :
Aug 1, 2018
Actual Primary Completion Date :
Jan 31, 2019
Actual Study Completion Date :
Jun 25, 2019

Arms and Interventions

Arm Intervention/Treatment
Experimental: Resistance exercise session

Acute isometric session, about 20 minutes.

Other: Resistance exercise session
Acute isometric exercise session performed with handgrip Jamar about 20 minutes monitored.
Other Names:
  • Aerobic exercise session

    		•
    Active Comparator: Aerobic exercise session

    Acute aerobic session, about 20 minutes.

    Other: Resistance exercise session
    Acute isometric exercise session performed with handgrip Jamar about 20 minutes monitored.
    Other Names:
  • Aerobic exercise session

    		•

    Outcome Measures

    Primary Outcome Measures

    1. Endothelial function [Pre and post 5 minutes exercise session]

      Flow-mediated dilatation technique

    Secondary Outcome Measures

    1. Arterial stiffness [Pre and post 5 minutes exercise session]

      Pulse wave velocity technique

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    20 Years to 80 Years
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    No
    Inclusion Criteria:

    • Post-acute myocardial infarction patients

    • Ergometric test 30 days after the infarction

    • Ejection fraction> 40% (Simpson's method)

    • Regular use of optimized drugs

    Exclusion Criteria:
    • Unable to perform the randomized exercise

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Alexandre Lehnen Porto Alegre Rio Grande Do Sul Brazil 90620-001

    Sponsors and Collaborators

    • Instituto de Cardiologia do Rio Grande do Sul

    Investigators

    • Principal Investigator: Alexandre Lehnen, PhD, Instituto de Cardiologia do Rio Grande do Sul

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    Instituto de Cardiologia do Rio Grande do Sul
    ClinicalTrials.gov Identifier:
    NCT04000893
    Other Study ID Numbers:
    • AMI and exercise
    First Posted:
    Jun 27, 2019
    Last Update Posted:
    Jun 27, 2019
    Last Verified:
    Jun 1, 2019
    Individual Participant Data (IPD) Sharing Statement:
    No
    Plan to Share IPD:
    No
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No
    Additional relevant MeSH terms:
    Myocardial Infarction
    Infarction

    Study Results

    No Results Posted as of Jun 27, 2019