ENDEMIC: Echocardiography by Non-cardiologist in Early Management of Patients With Chest Pain
Study Details
Study Description
Brief Summary
The aim of the study is to find out the benefit of echocardiography, which is performed by a physican without a cardiological or radiological specialty. In this case the echocardiography is used in the first contact with a patient with chest pain of unclear etiology. Possible benefit is rapid risk stratification of acute non-stemi coronary syndromes and differentiation from other serious conditions, such as pulmonary embolism or aortic dissection.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
N/A |
Detailed Description
Emergent echocardiography is reproducible method providing clinically significant information during primary survey of acute cardiovascular diseases. Possible benefit is the risk stratification of acute non-stemi coronary syndromes and differentiation from other serious conditions, such as pulmonary embolism or aortic dissection.
Step one - Education in Cardiac ultrasound. All physicians involved in ENDEMIC study have to undergo education program of heart ultrasonography. This curriculum fulfills BSE level one requirements. Candidates of this program have to make a defined number of ECHOcardiography studies under supervisor control. Every curriculum is finished by exam.
Step two - FOCUS in clinical practise Patients with chest pain are randomized into two groups by the even-odd rule.
Inclusion Criteria:
Chest pain ( Cardiovascular ethiology possible depends on anamnesis, physical examination and ECG ) Higher age than 18
Exclusion Criteria:
STEMI Pacemaker / ICD Pregnancy Performance status 4 ( Zubrod scale ) Informed Consent unsigned Prisoners
Step Three - Evaluation
Aims.:
Compare time to make a decision in these groups Compare time of stay at emergency department in these groups Compare time to invasive coronary angiography and revascularization (if available) Compare time to hospital dimission Occurrence of MACE in following 30 days
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Experimental: FOCUS group Group of patients with chest pain undergoing FOCUS ( Focused Cardiac Ultrasound ). Patients with odd registration number. |
Device: ECHOcardiography, Point-of-Care UZ
Emergent echocardiography is reproducible method providing clinically significant information during primary survey of acute cardiovascular diseases. Possible benefit is the risk stratification of acute non-stemi coronary syndromes and differentiation from other serious conditions, such as pulmonary embolism or aortic dissection. The aim of interest is to consider riscs and benefits of the ultrasound of heart done by non-cardiologist after standardized course.
|
| Active Comparator: Non-FOCUS group Patients with even registration number. |
Device: ECHOcardiography, Point-of-Care UZ
Emergent echocardiography is reproducible method providing clinically significant information during primary survey of acute cardiovascular diseases. Possible benefit is the risk stratification of acute non-stemi coronary syndromes and differentiation from other serious conditions, such as pulmonary embolism or aortic dissection. The aim of interest is to consider riscs and benefits of the ultrasound of heart done by non-cardiologist after standardized course.
|
Outcome Measures
Primary Outcome Measures
- Time of patient stay at Emergency Department [24 hours]
Time from initial contact with patient to patient discharge or hospital admission (minutes)
Secondary Outcome Measures
- Time of stay at hospital [28 days]
Time from hospital admission to hospital discharge (hours)
- Major adverse cardiovascular events [30 days]
Major adverse cardiovascular events are defined as composite endpoint of cardiovascular death, nonfatal myocardial infarction or unscheduled hospitalization due to cardiovascular disease (percent of patients in study groups).
Other Outcome Measures
- Time to Coronary Angiography [365 days]
Time from initial contact to coronary angiography (days)
- Accuracy of thoracic ultrasound exam provided by non-cardiologist [30 days]
All echocardiography records will be revised by skilled echocardiographist to assess the accuracy of performed examinations. All missed or erroneous finding resulting in alteration of patient management (especially wall motion abnormity, valvular disease and pericardial effusion) will be calculated. (quantity of erroneous or missed findings per record)
Eligibility Criteria
Criteria
Inclusion Criteria:
-
Chest pain ( Cardiovascular ethiology possible depends on anamnesis, physical examination and ECG )
-
Higher age than 18
Exclusion Criteria:
-
STEMI
-
Pacemaker / ICD
-
Pregnancy
-
Performance status 4 ( Zubrod scale )
-
Informed Consent unsigned
-
Prisoners
Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- University of Defence, Faculty of Military Health Sciences
Investigators
- Study Director: Martin Jakl, assoc.prof., University of Defense, Faculty of Military Health Sciences, Czech Republic
- Principal Investigator: Petr Grenar, MD, University of Defense, Faculty of Military Health Sciences, Czech Republic
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- 0000-0001-9433-296X