Racial Differences in Yoga-Induced Responses

• Sponsor: Texas State University (Other)
• Overall Status: Withdrawn
• CT.gov ID: NCT05598073
• Collaborator: (none)
• Enrollment: 0
• Location: 1
• Arm: 1
• Anticipated Duration (Months): 5.5
• Patients Per Site Per Month: 0

Study Details

Study Description

Brief Summary

The purpose of this study is to 1) determine whether racial differences are evident in resting arterial stiffness and ambulatory blood pressure between African Americans and Caucasians 2) compare heart rate, blood pressure and cytokine production responses to exercise (yoga) between African Americans and Caucasians; 3) compare isokinetic muscular strength between racial groups; and 4) determine if correlations exist between these measures.

Condition or Disease	Intervention/Treatment	Phase
Cardiovascular and Immune Responses to Yoga	Behavioral: Vinyasa yoga session	N/A

Study Design

• Study Type: Interventional
• Actual Enrollment: 0 participants
• Allocation: N/A
• Intervention Model: Single Group Assignment
• Masking: None (Open Label)
• Primary Purpose: Basic Science
• Official Title: Racial Differences in Yoga-Induced Cardiovascular and Immune Responses
• Anticipated Study Start Date: Jan 15, 2020
• Anticipated Primary Completion Date: Jun 1, 2020
• Anticipated Study Completion Date: Jul 1, 2020

Arms and Interventions

Arm	Intervention/Treatment
Experimental: 1-hour vinyasa yoga session Participants will complete a 1-hour vinyasa yoga DVD.	Behavioral: Vinyasa yoga session; One hour of vinyasa yoga will be completed.

Outcome Measures

Primary Outcome Measures

1. Arterial stiffness [Once at baseline]

   Cardio-ankle vascular index

2. Ambulatory blood pressure [Once at baseline]

   24 hours of ambulatory blood pressure monitoring

3. Isokinetic strength [Once at baseline]

   Isokinetic leg extension and flexion strength assessments at 60,120,210,300, and 400 degrees per second

4. Inflammatory markers [Once at baseline]

   Blood samples will be obtained and analyzed for interleukin-6 and tumor necrosis factor alpha

5. Inflammatory markers [Once 30 minutes into the 1-hour yoga session]

   Blood samples will be obtained and analyzed for interleukin-6 and tumor necrosis factor alpha

6. Inflammatory markers [Once immediately after the 1-hour yoga session]

   Blood samples will be obtained and analyzed for interleukin-6 and tumor necrosis factor alpha

Eligibility Criteria

Criteria

• Ages Eligible for Study: 18 Years to 39 Years
• Sexes Eligible for Study: Male
• Accepts Healthy Volunteers: Yes

Inclusion Criteria:

• Men between the ages of 18 and 39 (25 African American and 25 Caucasian) that are not professional or collegiate athletes

• Must exercise at least 3 days per week and have no more than 1 month of yoga practice.

Exclusion Criteria:

• Having stage 2 hypertension (>130 mmHg for systolic / >90 mmHg for diastolic) or higher or having taken BP medications within the 3 months prior to testing

• Infection within the previous 4 weeks

• Known renal disease

• Prior myocardial infarction

• Known coronary artery disease

• Personal history of stroke

• Heart failure

• Cardiac arrhythmias

• Chronic obstructive pulmonary disease

• Recent chest pain or dyspnea

• Orthopedic limitations that preclude the execution of yoga postures

• Current insulin dependence

• Chronic inflammatory conditions

• Blindness or deafness as participants will need to follow a yoga DVD in order to complete the session

• Having practiced yoga for more than 1 month

• Having parents of mixed racial backgrounds (i.e. both parents must be Caucasian or African American)

• Not being African American or Caucasian

• Being a professional or collegiate athlete

• Being insulin-dependent

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Stacy Hunter	San Marcos	Texas	United States	78666

Sponsors and Collaborators

• Texas State University

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: Texas State University
• ClinicalTrials.gov Identifier: NCT05598073
• Other Study ID Numbers: 6877
• First Posted: Oct 28, 2022
• Last Update Posted: Oct 28, 2022
• Last Verified: Jan 1, 2020

• Individual Participant Data (IPD) Sharing Statement: No
• Plan to Share IPD: No
• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No

Study Results

No Results Posted as of Oct 28, 2022