CBECD: Correlation Between Epistaxis and Cardiovascular Disease
Study Details
Study Description
Brief Summary
Investigators examine blood-pressure variance, several cardiovascular risk factors of patient with epistaxis. As a result of collected data, investigators look into correlation between epistaxis and hypertensive cardiovascular disorder.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Detailed Description
This study is prospective observational single blinded study.
A participant is visit in the ER who patient with epistaxis.
Investigators will enroll 50 patients with epistaxis. Exclusion criteria is that patient needs immediately treatment for hypertensive urgency or patient with nasal trauma.
Investigators examine blood-pressure (BP) at five times in Emergency Department (ED) and out-patient department (opd) of Otorhinolaryngology (OL) . Investigators explain this study and ask to write consent for participant. After proper management of epistaxis, investigators get blood sampling of the participant and, the participant has a reservation to "opd of cardiovascular division of Internal Medicine" (CV opd) in the hospital.
When the participant visit CV opd, the participant undergo 24-hours-BP-monitoring and Pulse wave velocity (PWV).
After that, the participant will be follow-up for 3 months.
Investigators collect 50 data from 50 participants as a registry and analyze the data.
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Spontaneous epistaxis A participant enroll if their age is over 18 with spontaneous epistaxis and their cause of visiting ER is spontaneous epistaxis. Exclusion criteria is that they needs immediately treatment for hypertensive urgency. And, they don't want to participate in this investigation. Investigators examine their blood-pressure variability and cardiovascular risk throughout their blood sample analysis. |
Biological: Blood-pressure variability
Day to Night Blood pressure variability
|
| Bleeding of wound A participant enroll if their age is over 18 with bleeding of wound and their cause of visiting ER is to bleed on wound. Exclusion criteria is that their wounds' condition is serious or their pain is much severe. And, they don't want to participate in this investigation. Investigators examine their blood-pressure variability and cardiovascular risk throughout their blood sample analysis. |
Biological: Blood-pressure variability
Day to Night Blood pressure variability
|
Outcome Measures
Primary Outcome Measures
- Cholesterol level in each group [1 day]
- BP variability level in each group [1 day]
- Pulse wave velocity in each group [1 day]
Secondary Outcome Measures
- Smoking History in each group [1 day]
Example = "12 pack-year"
- Body Mass Index in each group [1 day]
Eligibility Criteria
Criteria
Group A
Inclusion Criteria:
- age is over 18 with spontaneous epistaxis
Exclusion Criteria:
-
they needs immediately treatment for hypertensive urgency.
-
they don't want to participate in this investigation.
Group B
Inclusion Criteria:
- age is over 18 with bleeding of wound
Exclusion Criteria:
-
their wounds' condition is serious or their pain is much severe.
-
they don't want to participate in this investigation.
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Hanyang University Guri Hospital | Guri-si | Gyeonggi-do | Korea, Republic of | 471-701 |
Sponsors and Collaborators
- Hanyang University
Investigators
- Study Chair: JUNGHOON SHIN, M.D., Ph.D., Hanyang University
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- Gurivengers