AsuRiesgo: Cardiovascular Risk Factors in an Ambulatory Urban Patient Population
Study Details
Study Description
Brief Summary
According to WHO estimations, cardiovascular diseases (CVDs) are the number one cause of death globally. More people die annually from CVDs than from any other cause. An estimated 17.5 million people died from CVDs in 2005, representing 30% of all global deaths. Of these deaths, an estimated 7.6 million were due to coronary heart disease and 5.7 million were due to stroke.
Over 80% of CVD deaths take place in low- and middle-income countries and occur almost equally in men and women. In Paraguay, prevalence of classic risk factors, as well as new ones, like the metabolic syndrome are not completely known.
Government health policies in industrialized countries are focusing on programs to modify cardiovascular risk factors. In developing countries, prevention of coronary heart disease and stroke through modification of cardiovascular risk factors are not playing a large role at the moment.
The aim of this study is to define the effects of changes in lifestyle on cardiovascular risk factors, when added to optimized standard pharmacological therapy for arterial hypertension, diabetes mellitus and hyperlipidemia, in an ambulatory urban patient population.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| asuriesgo unselected outpatient population |
Behavioral: Dietary and nutritional modification
Behavioral: Stop smoking
Behavioral: Regular physical activities
Behavioral: Weight reduction to normal ranges
Behavioral: Regular intake of polyphenols, esp. from Ilex paraguayensis
|
Outcome Measures
Primary Outcome Measures
- cardiovascular mortality [one year]
Secondary Outcome Measures
- mortality, other causes [one year]
- acute myocardial infarction [one year]
- stroke [one year]
- acute coronary syndrome [one year]
Eligibility Criteria
Criteria
Inclusion Criteria:
- all ambulatory patients, with age 18 years or older
Exclusion Criteria:
- no exclusion criteria provided, particularly for the first, epidemiological part of the study
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Hospital Central Instituto de Prevision Social | Asuncion | Dep. Central | Paraguay | 1749 |
Sponsors and Collaborators
- Heidelberg University
Investigators
- Principal Investigator: Derliz Mereles, MD, Heidelberg University
Study Documents (Full-Text)
None provided.More Information
Additional Information:
Publications
- Jimenez JT, Palacios M, Cañete F, Barriocanal LA, Medina U, Figueredo R, Martinez S, de Melgarejo MV, Weik S, Kiefer R, Alberti KG, Moreno-Azorero R. Prevalence of diabetes mellitus and associated cardiovascular risk factors in an adult urban population in Paraguay. Diabet Med. 1998 Apr;15(4):334-8.
- Ramirez MO, Pino CT, Furiasse LV, Lee AJ, Fowkes FG. Paraguayan National Blood Pressure Study: prevalence of hypertension in the general population. J Hum Hypertens. 1995 Nov;9(11):891-7.
- AsuRiesgo