ERGO-RISC: Cardiovascular Risk Factors on Electrocardiographically and Hemodynamics Responses to Treadmill Exercise Test
Study Details
Study Description
Brief Summary
The goal of this observational cross-sectional study is to analyze the effect of cardiovascular risk factors in healthy and asymptomatic populations. The main questions it aims to answer are:
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Does the combination of the presence of different risk factors increase the risk for abnormalities appearing on electrocardiograms, such as ischemia, arrhythmia, and hemodynamics effects during and at the peak of effort of treadmill exercise test?
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What are the main differences observed in the recovery period? Participants will answer an anamnesis of risk factors such as sex, race, age, familiar history of coronary artery disease, overweight or obesity, smoking, stress, and physical activity practice and perform treadmill exercise test on Ellestad protocol. If there a comparison groups: Researchers will compare individuals with most risk factors with those without, to see the cardiovascular responses.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
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Detailed Description
The main outcomes broad the effect of simples and easy doccumented cardiovascular risk factors such as sex, race, age, familiar history of coronary artery disease, overweight or obesity, smoking, stress, and physical inactivity on electrocardiogram and hemodinamics abnormalities during and after exercise treadmill exercise test.
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Healthy controls Volunteers will perform treadmill exercise tests. It will be monitored electrocardiogram, heart rate, and blood pressure in the rest state, under exercise, and in the recovery. |
Diagnostic Test: Treadmill exercise stress test
Ellestad protocol will be applied in all subjects up to fatigue and recovery will be monitored.
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Outcome Measures
Primary Outcome Measures
- ECG abnormalities and risk factors [1 year]
Electrocardiogram suggestive of myocardial ischemia
Eligibility Criteria
Criteria
Inclusion Criteria:
- Subjects that can complete the treadmill exercise test with the Ellestad protocol with 6 minutes of recovery.
Exclusion Criteria:
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Use of remedies for blood pressure, glycemia, cholesterol, and serum lipids;
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Symptomatically subjects;
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Electrocardiogram that are not able to be interpreted;
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Blood pressure in rest state ≥180 mmHg and ≥110 mmHg, for systolic and diastolic, respectively.
Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- University of Sao Paulo
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- Pró-Coração