Comparison of Acute Sauna With Exercise and Sauna

Sponsor
University of Jyvaskyla (Other)
Overall Status
Completed
CT.gov ID
NCT04556422
Collaborator
Finnish Foundation for Cardiovascular Research (Other), Business Finland (Other), Harvia Finland Oy (Other)
72
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4
18

Study Details

Study Description

Brief Summary

Sauna bathing has been associated with a lower risk for cardiovascular disease (CVD) outcomes, improved vascular endothelial and cardiac function, reduced oxidative stress and lower blood pressure. Earlier studies conducted by the investigators have showed positive alterations of arterial stiffness and hemodynamics through sauna bathing.

Some studies have sought to utilize sauna bathing as an intervention after exercise with promising and synergistic results, although the effects on populations with cardiovascular risk factors are less clear. Furthermore, studies investigating the use of both exercise and sauna bathing in combination has been somewhat limited. However, results from some studies speculate that adjunctive exercise and sauna interventions may be useful for aging and clinical patient population groups.

Given that heat therapy and sauna use is gaining more worldwide popularity, the investigators sought to compare the acute hemodynamic effects between sauna use alone and a short bout of exercise followed by sauna exposure. It was hypothesize that the combination of exercise and sauna will elicit greater changes than sauna alone. To achieve this, we standardized the protocol duration (30 minutes).

Condition or Disease Intervention/Treatment Phase
  • Other: Aerobic exercise
  • Other: Sauna bathing
N/A

Detailed Description

In this crossover trial, all study participants underwent two interventions, each on a separate occasion (>72 hours apart). A standalone 30-minute sauna at 75°C (S), and 15-minutes of cycling on the stationary bike at 75% maximum heart rate, followed by 15-minutes of sauna exposure (ES). A cycling exercise test was conducted on a separate day prior to the experiment to ascertain individual maximal exercise heart rates, which was then used to calculate individual 75% maximum.

After the first 15-minute period of S, the participants left the sauna room to have a quick shower (<30 seconds) before going back for the second 15-minute period. The same sauna bathing room (75°C) was used for all participants and the cycling exercise was conducted within 10 meters of the sauna room to minimize transit time during ES. Participants were instructed to abstain from eating 2h, caffeine 12h and alcohol 24h prior to the measurements. Food intake was not standardized. Fluid was consumed ad libitum. A medical physician was in attendance at all times and participants were allowed to leave the sauna or stop the experiment at any time if they felt uncomfortable.

Brachial blood pressures and pulse wave velocity (PWV) as a measure of arterial stiffness, were taken in their respective order at three different time points; before (PRE), immediately after (POST), and after a 30-minute recovery (POST30). Transit time from the cessation of the intervention to POST measurements were kept under 60 seconds. All measurements were performed by the same assessor to minimize ascertainment biases.

Participants were permitted to take a quick shower (<30 seconds) before POST measurements were taken. Water temperature or the shower was not controlled and participants could freely select their desired temperature. Thereafter, they were instructed to rest in a designated waiting lounge (mean temperature 21°C) in a seated position for a duration of 30-minutes before the last measurement (POST30) was taken.

Study Design

Study Type:
Interventional
Actual Enrollment :
72 participants
Allocation:
Non-Randomized
Intervention Model:
Crossover Assignment
Masking:
None (Open Label)
Primary Purpose:
Basic Science
Official Title:
Standalone Sauna Versus Exercise Followed by Sauna on Cardiovascular Function in Non-naïve Sauna Users
Actual Study Start Date :
Aug 1, 2018
Actual Primary Completion Date :
Oct 30, 2018
Actual Study Completion Date :
Dec 1, 2018

Arms and Interventions

Arm Intervention/Treatment
Active Comparator: Sauna alone

Sauna exposure for 30 minutes

Other: Sauna bathing
Passive heat exposure

Experimental: Exercise and Sauna

Cycling exercise for 15 minutes followed by sauna for 15 minutes

Other: Aerobic exercise
15 minutes of aerobic exercise using stationary bicycle

Other: Sauna bathing
Passive heat exposure

Outcome Measures

Primary Outcome Measures

  1. Brachial blood pressure [Single session (30 minutes)]

    Systolic and diastolic blood pressure

  2. Central blood pressure [Single session (30 minutes)]

    Systolic and diastolic blood pressure measured using ECG and Pulsepen

Secondary Outcome Measures

  1. Arterial Stiffness [Single session (30 minutes)]

    Pulsewave velocity (PWV)

  2. Augmentation Index [Single session (30 minutes)]

    Supplement to PWV

Eligibility Criteria

Criteria

Ages Eligible for Study:
30 Years to 75 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
  • Free of a prior diagnosis of CVD, exhibits at least one of the following cardiovascular risk factors: a history of smoking, hyperlipidemia, hypertension, diabetes, obesity, or family history of coronary heart disease (CHD).
Exclusion Criteria:
  • recent musculoskeletal injuries or surgery (less than 6 months ago), mental illnesses, under 30 years of age or over 75 at time of recruitment, health conditions that may contraindicate study parameters.

Contacts and Locations

Locations

Site City State Country Postal Code
1 University of Jyväskylä Jyväskylä Keski-Suomi Finland 40014

Sponsors and Collaborators

  • University of Jyvaskyla
  • Finnish Foundation for Cardiovascular Research
  • Business Finland
  • Harvia Finland Oy

Investigators

  • Principal Investigator: Jari A Laukkanen, PhD/MD, Central Finland Central Hospital

Study Documents (Full-Text)

None provided.

More Information

Publications

Responsible Party:
University of Jyvaskyla
ClinicalTrials.gov Identifier:
NCT04556422
Other Study ID Numbers:
  • Sauna
First Posted:
Sep 21, 2020
Last Update Posted:
Sep 23, 2020
Last Verified:
Sep 1, 2020
Individual Participant Data (IPD) Sharing Statement:
No
Plan to Share IPD:
No
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Keywords provided by University of Jyvaskyla

Study Results

No Results Posted as of Sep 23, 2020