Exercise & Diet Effects on CV Risk in Firefighters

Sponsor
University of New Hampshire (Other)
Overall Status
Recruiting
CT.gov ID
NCT03344198
Collaborator
American Heart Association (Other)
125
1
3
53.2
2.4

Study Details

Study Description

Brief Summary

The study will explore the capacity for a lifestyle modification in firefighters to improve blood pressure, blood vessel stiffness, inflammation, and reduce oxidative stress. The study will be a pre- post-testing controlled trial with three groups. The intervention will be a weekly circuit workout program and a Mediterranean (high fruit/vegetable) diet. The groups will be firefighters with >10yrs experience, firefighters with <10yrs experience, and control Non-firefighters.

Condition or Disease Intervention/Treatment Phase
  • Behavioral: Circuit Training exercise & Modified Mediterranean diet
N/A

Detailed Description

Recent statistics from the American Heart Association (AHA) have reported that >92% of adults in the U.S. meet at least 1 metric for cardiovascular disease risk factors. In firefighters, this increased risk is especially concerning. The National Fire Protection Agency (NFPA) estimates there are around 1.3 million firefighters in the United States, 70% of which are volunteer. The prevalence of impaired cardiovascular health is higher in firefighters than in the general population and the leading line-of-duty death (LODD) cause is cardiac related. It is known that exercise and diet mitigate cardiovascular disease risk. Meeting the physical activity guidelines remains a target of ideal cardiovascular health and a major public health concern. However, the NFPA does not require volunteer fire companies to have a fitness program for their crew, and sadly less than a third of the stations actually do. And importantly, cardiovascular-related LODD remains a major issue in the firefighter population. The results could guide clinical treatment for firefighters and may therefore reduce cardiac-related LODD.

Study Design

Study Type:
Interventional
Anticipated Enrollment :
125 participants
Allocation:
Non-Randomized
Intervention Model:
Parallel Assignment
Masking:
None (Open Label)
Primary Purpose:
Prevention
Official Title:
Effects of Combined Diet & Exercise Intervention on Cardiovascular Risk Factors in Firefighters & Civilians
Actual Study Start Date :
Nov 25, 2018
Anticipated Primary Completion Date :
Dec 1, 2022
Anticipated Study Completion Date :
May 1, 2023

Arms and Interventions

Arm Intervention/Treatment
Experimental: Firefighter (Veteran) Group

Firefighters with >10yrs experience. Circuit Training exercise & Modified Mediterranean diet

Behavioral: Circuit Training exercise & Modified Mediterranean diet
Participants will receive circuit training program and a modified Mediterranean diet program. Educational sessions, serving size training, and portion containers will be provided. Participants will also receive individualized support throughout the 6 week intervention.

Experimental: Firefighter (Novice) Group

Firefighters with <10yrs experience. Circuit Training exercise & Modified Mediterranean diet

Behavioral: Circuit Training exercise & Modified Mediterranean diet
Participants will receive circuit training program and a modified Mediterranean diet program. Educational sessions, serving size training, and portion containers will be provided. Participants will also receive individualized support throughout the 6 week intervention.

Experimental: Control Non-Firefighter Group

Non-Firefighter adults. Circuit Training exercise & Modified Mediterranean diet

Behavioral: Circuit Training exercise & Modified Mediterranean diet
Participants will receive circuit training program and a modified Mediterranean diet program. Educational sessions, serving size training, and portion containers will be provided. Participants will also receive individualized support throughout the 6 week intervention.

Outcome Measures

Primary Outcome Measures

  1. Change in blood pressure [Pre-Intervention (Week 0), Post-Intervention (Week 6)]

    Blood pressure surge response to alarm will be measured by ambulatory blood pressure monitor

Secondary Outcome Measures

  1. Change in vascular stiffness [Pre-Intervention (Week 0), Post-Intervention (Week 6)]

    Stiffness will be measured by pulse wave velocity

  2. Change in cardiopulmonary fitness [Pre-Intervention (Week 0), Post-Intervention (Week 6)]

    Fitness will be measured by treadmill test

  3. Change in body composition [Pre-Intervention (Week 0), Post-Intervention (Week 6)]

    Body composition will be measured by bioelectrical impedance

  4. Change in inflammation [Pre-Intervention (Week 0), Post-Intervention (Week 6)]

    Inflammation will be measured by assay of circulating bio-markers through blood draw.

  5. Change in oxidative stress [Pre-Intervention (Week 0), Post-Intervention (Week 6)]

    Oxidative stress will be measured by assay of circulating antioxidant bio-markers through blood draw.

Eligibility Criteria

Criteria

Ages Eligible for Study:
18 Years to 70 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:
  • Adult

  • Able to Exercise

Exclusion Criteria:
  • More than one anti-hypertensive medication

  • More than one cholesterol medication

  • Diabetic

  • Prior Cardiac incident

Contacts and Locations

Locations

Site City State Country Postal Code
1 University of New Hampshire, Department of Kinesiology, College of Health and Human Services Durham New Hampshire United States 03824

Sponsors and Collaborators

  • University of New Hampshire
  • American Heart Association

Investigators

  • Principal Investigator: Deborah L Feairheller, PhD, University of New Hampshire

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
University of New Hampshire
ClinicalTrials.gov Identifier:
NCT03344198
Other Study ID Numbers:
  • UNH-005-8242-01
First Posted:
Nov 17, 2017
Last Update Posted:
Oct 7, 2021
Last Verified:
Sep 1, 2021
Individual Participant Data (IPD) Sharing Statement:
Undecided
Plan to Share IPD:
Undecided
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Keywords provided by University of New Hampshire

Study Results

No Results Posted as of Oct 7, 2021