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CAROTIS cFT IN PREDICTION OF HYPOTENSION

Sponsor
Cukurova University (Other)
Overall Status
Not yet recruiting
CT.gov ID
NCT05896514
Collaborator
(none)
120
Enrollment
2.9
Anticipated Duration (Months)

Study Details

Study Description

Brief Summary

The aim of our study is to determine the predictive value of pre-anesthesia FTc for hypotension that may develop after general anesthesia induction in patients over 65 years of age and to investigate the correlation between pre-anesthesia FTc and the magnitude of the maximum decrease in systolic blood pressure from the pre-anaesthetic value.

Condition or Disease Intervention/Treatment Phase
  • Device: ultrasound-guided carotid artery flow time measurement

Detailed Description

The FTc value of the patients to be included in the study will be measured by ultrasonography 10 minutes before the induction of anesthesia.After the measurement, the patients will be monitored with 3-lead electrocardiography, pulse oximetry and noninvasive blood pressure in the operating room. Before induction of general anesthesia, systolic blood pressure (SBP), diastolic blood pressure (DBP), mean blood pressure (MAP), oxygen saturation and heart rate will measured for 3 minutes at 1-minute intervals. Induction of anesthesia with 1-2 mg/kg propofol, muscle relaxation will be achieved with 0.6 mg/kg intravenous rocuronium. During mask ventilation, 1-2% concentration of sevoflurane and 50-50% oxygen-nitrous oxide will be used. After the anesthesia induction, SBP, DBP, MAP, oxygen saturation and heart rate will be measured for 3 minutes at 1-minute intervals.

Hypotension; defined as a 30% reduction in SBP or a 20% reduction in MAP, or an absolute SBP below 90 mm Hg and MAP below 65 mm Hg within 3 minutes of induction of general anesthesia.Intravenous (iv) noradrenaline and/or iv crystalloid will be used in the treatment of hypotension.

Study Design

Study Type:
Observational
Anticipated Enrollment :
120 participants
Observational Model:
Other
Time Perspective:
Prospective
Official Title:
THE ROLE OF CAROTIS FLOW TIME IN PREDICTION OF HYPOTENSION AFTER ANESTHESIA INDUCTION IN ELDERLY PATIENTS
Anticipated Study Start Date :
Jun 3, 2023
Anticipated Primary Completion Date :
Aug 4, 2023
Anticipated Study Completion Date :
Aug 31, 2023

Outcome Measures

Primary Outcome Measures

  1. anesthesia induction related hypotension [at 1 minute after anesthesia induction, at 2 minutes after anesthesia induction, at 3 minutes anesthesia induction]

    The aim of our study is to determine the predictive value of pre-anesthesia FTc for hypotension that may develop after general anesthesia induction in patients over 65 years of age.

Eligibility Criteria

Criteria

Ages Eligible for Study:
65 Years and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:

  • 65 years old

  • undergoing elective surgery under general anesthesia

Exclusion Criteria:

  • Mean arterial pressure < 70 mmHg

  • Systolic blood pressure > 180 mmHg

  • Diastolic blood pressure > 110 mmHg

  • < 65 years old

  • Carotid artery stenosis > 50%

  • ASA > 3

  • Left ventricle ejection fraction < 40%

  • Severe peripheral vascular disease

  • Implanted pacemacer

  • Autonomic nervous system disorders

  • Heart valve disease

  • Chronic kidney disease

  • Emergency surgery

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

  • Cukurova University

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
mediha turktan, associate professor, Cukurova University
ClinicalTrials.gov Identifier:
NCT05896514
Other Study ID Numbers:
  • Carotid cFT
First Posted:
Jun 9, 2023
Last Update Posted:
Jun 9, 2023
Last Verified:
May 1, 2023
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms:
Hypotension

Study Results

No Results Posted as of Jun 9, 2023