Neurodynamic Sequencing in Patients With Carpal Tunnel Syndrome

• Sponsor: Riphah International University (Other)
• Overall Status: Recruiting
• CT.gov ID: NCT05905107
• Collaborator: (none)
• Enrollment: 56
• Location: 1
• Arms: 2
• Anticipated Duration (Months): 6.8
• Patients Per Site Per Month: 8.2

Study Details

Study Description

Brief Summary

Carpal tunnel syndrome is a compressive neuropathy of median nerve in the fascial tunnel at wrist which causes pain, numbness ,and tingling in the extremities. Common treatment options used in the treatment of carpal tunnel syndrome are conservative and surgical treatment option is better, this question is still a topic requiring more and more clinical trials. Neuromobilisation described by Butler is one of the treatment options which are used in the treatment of carpal tunnel syndrome in conjunction with other conservative measures.

This proposed study will find out the effectiveness of Neuromobilisation in treatment of carpal tunnel syndrome. As there is very little evidence available which Neuromobilisation technique is effective and what are the types of patients which can get benefit from this technique. This study will find out the effect of Neuromobilisation in patients suffering from carpal tunnel syndrome of non traumatic origin. This is a randomized clinical trial. Target population is patients suffering from carpal tunnel syndrome of non-traumatic origin. Data will be collected from District Headquarter Hospital Faisalabad. This study will include 56 participants according to the selection criteria. The participants will be randomly divided into two groups through sealed opaque envelop method.

Group A will recruit 28 patients which fulfill the inclusion criteria. These patients will be treated by nerve sequencing proximal to distal in 3 sets of 15 repetitions in one session on alternate days for 4 weeks. Group B will recruit 28 patients which fulfill the inclusion criteria. These patients will be treated by nerve sequencing distal to proximal in 3 sets of 10 repetitions in one session for 4 weeks. The Statistical analysis will be performed through SPSS Software 21.

Condition or Disease	Intervention/Treatment	Phase
Carpal Tunnel Syndrome	Other: Neurodynamic Slider Technique from Proximal to Distal; Other: Neurodynamic Slider Technique from Distal to Proximal	N/A

Study Design

• Study Type: Interventional
• Anticipated Enrollment: 56 participants
• Allocation: Randomized
• Intervention Model: Parallel Assignment
• Masking: Single (Outcomes Assessor)
• Primary Purpose: Treatment
• Official Title: Effects of Neurodynamic Sequencing on Pain, Wrist Range of Movement and Functional Disability in Patients With Carpal Tunnel Syndrome
• Actual Study Start Date: Jan 4, 2023
• Anticipated Primary Completion Date: Jul 15, 2023
• Anticipated Study Completion Date: Jul 30, 2023

Arms and Interventions

Arm	Intervention/Treatment
Experimental: Interventional Group A These patients will be treated by nerve sequencing proximal to distal in 3 sets of 15 repetitions in one session on alternate days for 4 weeks. For this, participants will be given a comfortable supine lying position. ULTT method will be implemented to the ipsilateral upper limb given in the table below	Other: Neurodynamic Slider Technique from Proximal to Distal; Neurodynamic Slider Technique from proximal to distal at wrist, elbow and neck
Active Comparator: Interventional Group B These patients will be treated by nerve sequencing distal to proximal in 3 sets of 10 repetitions in one session for 4 weeks. For this, participants will be given a comfortable supine lying position. ULTT method will be implemented to the ipsilateral upper limb	Other: Neurodynamic Slider Technique from Distal to Proximal; Neurodynamic Slider Technique from proximal to distal at wrist, elbow and neck

Outcome Measures

Primary Outcome Measures

1. Pain at wrist joint [4 weeks]

   Pain will be assessed by using Numerical Pain Rating Scale Pain will be assessed by using Numerical Pain Rating Scale

2. Wrist Range of Movement at wrist joint [4 weeks]

   Range of motion will be assessed by using Goniometer

3. Functional Ability at wrist joint [4 weeks]

   Functional Ability will be assessed by using Boston Carpal tunnel syndrome

Eligibility Criteria

Criteria

• Ages Eligible for Study: 25 Years to 55 Years
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Inclusion Criteria:

• Patients positive for provocative test ( Phalen's test, Wrist decompression test and tinnel test).

Exclusion Criteria:

• Inflammation around the wrist

• Tumor around the wrist

• Rheumatoid Arthritis

• Osteoporosis

• Joint Hypermobility

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	District Headquarters Hospital	Faisalābad	Punjab	Pakistan	38000

Sponsors and Collaborators

• Riphah International University

Investigators

• Principal Investigator: Sahreen Anwar, Ph.D, Riphah International University

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: Riphah International University
• ClinicalTrials.gov Identifier: NCT05905107
• Other Study ID Numbers: REC_FSD_00325
• First Posted: Jun 15, 2023
• Last Update Posted: Jun 15, 2023
• Last Verified: Jun 1, 2023

• Individual Participant Data (IPD) Sharing Statement: No
• Plan to Share IPD: No
• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No
• Additional relevant MeSH terms: Carpal Tunnel Syndrome; Syndrome

Study Results

No Results Posted as of Jun 15, 2023