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Case Notes Review on Patients With Hereditary Haemorrhagic Telangiectasia

Sponsor
Imperial College London (Other)
Overall Status
Unknown status
CT.gov ID
NCT00230685
Collaborator
The Margaret Hayton HHT Fund (Other)
500
Enrollment
1
Location
216
Duration (Months)
2.3
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The Hammersmith Hospital provides a clinical service for patients with Hereditary haemorrhagic telangiectasia and pulmonary arteriovenous malformations that is unique in the United Kingdom. Measurements obtained as part of standard clinical practice that has evolved since 1985 allow us to assess whether particular groups of individuals that we see are more prone to recognised complications such as strokes, brain abscesses, pregnancy related complications or pulmonary hypertension. We hypothesise that certain clinical characteristics will predict the susceptibility of individuals to particular complications.

Condition or Disease Intervention/Treatment Phase

    Study Design

    Study Type:
    Observational
    Anticipated Enrollment :
    500 participants
    Observational Model:
    Cohort
    Time Perspective:
    Prospective
    Official Title:
    Hammersmith Hospital Patients With Pulmonary Arteriovenous Malformations (PAVMs) and Hereditary Haemorrhagic Telangiectasia
    Study Start Date :
    Jan 1, 2000
    Anticipated Primary Completion Date :
    Jan 1, 2018
    Anticipated Study Completion Date :
    Jan 1, 2018

    Outcome Measures

    Primary Outcome Measures

    1. Stroke [Prospective]

    2. Venous thromboemboli (VTE) [Prospective]

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    N/A and Older
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    No
    Inclusion Criteria:
    • Patients attending Hammersmith Hospital
    Exclusion Criteria:
    • None

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Respiratory Medicine, Hammersmith Hospital London United Kingdom W12 0NN

    Sponsors and Collaborators

    • Imperial College London
    • The Margaret Hayton HHT Fund

    Investigators

    • Principal Investigator: Claire L Shovlin, Imperial College London

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    Imperial College London
    ClinicalTrials.gov Identifier:
    NCT00230685
    Other Study ID Numbers:
    • IC/CLS2
    First Posted:
    Oct 3, 2005
    Last Update Posted:
    May 29, 2015
    Last Verified:
    Aug 1, 2008
    Keywords provided by Imperial College London
    Pulmonary arteriovenous malformations
    Additional relevant MeSH terms:
    Telangiectasis
    Arteriovenous Malformations
    Telangiectasia, Hereditary Hemorrhagic

    Study Results

    No Results Posted as of May 29, 2015