Study of the Causes of the Breakdown of Muscle Fibers in Hospitalized Patients

Sponsor
National Taiwan University Hospital (Other)
Overall Status
Unknown status
CT.gov ID
NCT01022450
Collaborator
(none)
2,500
1

Study Details

Study Description

Brief Summary

  1. Analyze the various causes of breakdown of muscle fibers in hospitalized patients.

  2. Analyze the characteristics of these patients in Taiwan (including the drugs history, risk factors and the incidence of complications).

Condition or Disease Intervention/Treatment Phase

    Detailed Description

    1. Find the causes of breakdown of muscle fibers in hospitalized patients through medical record review.
    • especially drug-related
    1. Find the risk factors of muscle fibers breakdown.

    Study Design

    Study Type:
    Observational
    Anticipated Enrollment :
    2500 participants
    Observational Model:
    Case-Only
    Time Perspective:
    Retrospective
    Official Title:
    Rhabdomyolysis - A Retrospective Study in Hospitalized Patients
    Study Start Date :
    Nov 1, 2009
    Anticipated Primary Completion Date :
    Nov 1, 2010

    Outcome Measures

    Primary Outcome Measures

      Eligibility Criteria

      Criteria

      Ages Eligible for Study:
      N/A and Older
      Sexes Eligible for Study:
      All
      Accepts Healthy Volunteers:
      No
      Inclusion Criteria:
      • Patients who admitted to The National Taiwan University Hospital during 2003/1/1~2008/12/31 with the following discharge diagnosis: myoglobinuria, rhabdomyolysis, myopathy, toxic myopathy, malignant hyperthermia, neuroleptic malignant syndrome, polymyositis, myalgia and had acute neuromuscular illness presentations and serum creatinine kinase (CK) more than 5 times the upper limit of normal (male > 900 IU/L; female > 835 IU/L).
      Exclusion Criteria:
      • Patients with recent myocardial infarction or stroke, unless clinical history, examination, or electromyography showed a concomitant myopathy.

      Contacts and Locations

      Locations

      Site City State Country Postal Code
      1 National Taiwan University Hospital Taipei Taiwan 10051

      Sponsors and Collaborators

      • National Taiwan University Hospital

      Investigators

      • Principal Investigator: Fe-Lin L Wu, MSCP, PhD, Graduate Institute of Clinical Pharmacy, National Taiwan University

      Study Documents (Full-Text)

      None provided.

      More Information

      Publications

      None provided.
      Responsible Party:
      , ,
      ClinicalTrials.gov Identifier:
      NCT01022450
      Other Study ID Numbers:
      • 200911033R
      First Posted:
      Dec 1, 2009
      Last Update Posted:
      Dec 1, 2009
      Last Verified:
      Nov 1, 2009

      Study Results

      No Results Posted as of Dec 1, 2009