The CCUS Based Characteristic of Hemodynamic and Lung Pathology in Early Stage of Shock in ICU: The Epidemic and Prognostic Value

Sponsor

West China Hospital (Other)

Overall Status

Completed

CT.gov ID

NCT03082326

Collaborator

(none)

181

Enrollment

Location

Duration (Months)

12.9

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Shock is a common condition in critical care unit (ICU). It is extremely important that the patient accepts early goal-directed therapy (EGDT) treatment in the early stage of shock. However, several studies failed to demonstrate that the well used variables such as CVP and others could direct to a better treatment. In recent years, critical care ultrasound (CCUS) has been respected as a reliable noninvasive tool and widely used in ICU practice. With CCUS the investigators can accurately acquired the detailed information of the characteristic of the hemodynamics and lung pathology (the systole and diastole function, volume status, valve insufficiency, lung, edema, consolidation, and pleural effusion, etc.). To the investigators knowledge, there is no study investigating the epidemic of such ultrasonic variables and its value to predict to outcome. The aim of this study is to investigate the epidemic and the prognostic value of CCUS Based Characteristic of Hemodynamic and Lung pathology in Early Stage of Shock in patients admitted in ICU.

Condition or Disease	Intervention/Treatment	Phase
Shock

Detailed Description

Adult patients who admitted to the intensive care unit of West China hospital of sichuan university with shock from April 2016 to April 2017 enrolled.

Study Design

Study Type:

Observational

Actual Enrollment :

181 participants

Observational Model:

Other

Time Perspective:

Prospective

Official Title:

The Critical Care Ultrasound Based Characteristic of Hemodynamic and Lung Pathology in Early Stage of Shock in ICU: The Epidemic and Prognostic Value

Study Start Date :

Apr 5, 2016

Actual Primary Completion Date :

Jun 6, 2017

Actual Study Completion Date :

Jun 6, 2017

Outcome Measures

Primary Outcome Measures

all cause mortality [28 days]

Secondary Outcome Measures

length of mechanical ventilation [through study completion, an average of 28 days]
ICU length of stay [through study completion, an average of 28 days]
hospital length of stay [through study completion, an average of 28 days]

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Inclusion Criteria:

SBP<90 mm Hg or MAP <70 mm Hg or SBP decrease >40mmHg or need vasoactive drugs;
Skin that is cold and clammy, capillary refill time >4.5s, urine output of <0.5ml/Kg.hr and lactate>2mmol/L;
SHOCK presented within 6 hr.