A Chatbot Intervention for Reducing HPV Vaccine Hesitancy

• Sponsor: University of Maryland, College Park (Other)
• Overall Status: Recruiting
• CT.gov ID: NCT05959564
• Collaborator: (none)
• Enrollment: 600
• Location: 1
• Arms: 3
• Anticipated Duration (Months): 1
• Patients Per Site Per Month: 589.1

Study Details

Study Description

Brief Summary

The goal of this project is to test the efficacy of a chatbot intervention for reducing HPV vaccine hesitancy among African American parents. An online experiment will be conducted to test the effectiveness of the chatbot intervention with African American parents. Results of this project will inform future communication interventions for reducing vaccine hesitancy among African American parents.

Condition or Disease	Intervention/Treatment	Phase
Cervical Cancer; Anal Cancer; Penile Cancer	Behavioral: Personalized Chatbot Intervention; Behavioral: Non-Personalized Chatbot Intervention; Behavioral: No Chatbot Control	N/A

Detailed Description

The goal of this project is to test the efficacy of a chatbot intervention for reducing HPV vaccine hesitancy among African American parents. An online survey-experiment will be conducted. In the survey-experiment, participants will first answer questions related to their attitudes toward childhood vaccines and see a brief CDC message about HPV vaccine. Then they will be directed to interact with a chatbot designed to deliver personalized HPV vaccine messages (tailored to the participant's personality) or a similar chatbot with non-personalized messages. There will also be a control condition where participants will see the brief CDC message about HPV vaccine but will not interact with any chatbot. All participants will answer questions related to their attitudes toward HPV vaccination, intentions to vaccinate their children, as well as other message response measures.

Study Design

• Study Type: Interventional
• Anticipated Enrollment: 600 participants
• Allocation: Randomized
• Intervention Model: Parallel Assignment
• Masking: Single (Participant)
• Primary Purpose: Prevention
• Official Title: A Chatbot Intervention for Reducing HPV Vaccine Hesitancy
• Anticipated Study Start Date: Jul 1, 2023
• Anticipated Primary Completion Date: Aug 1, 2023
• Anticipated Study Completion Date: Aug 1, 2023

Arms and Interventions

Arm	Intervention/Treatment
Experimental: Personalized Chatbot Condition After reading a standard CDC HPV vaccine message, participants will interact with a chatbot designed to deliver personalized HPV vaccine messages (i.e., tailored to their personalities).	Behavioral: Personalized Chatbot Intervention; In this intervention, participants will first see a standard CDC HPV vaccine message. After that they will be invited to interact with a chatbot designed to deliver additional HPV vaccine messages, which are tailored to their personalities.
Experimental: Non-Personalized Chatbot Condition After reading a standard CDC HPV vaccine message, participants will interact with a chatbot designed to deliver HPV vaccine messages, which are not tailored to their personalities.	Behavioral: Non-Personalized Chatbot Intervention; In this intervention, participants will first see a standard CDC HPV vaccine message. After that they will be invited to interact with a chatbot designed to deliver additional HPV vaccine messages, which are not tailored to their personalities.
Active Comparator: No Chatbot Control Condition Participants will read a standard CDC HPV vaccine message without interacting with any chatbot that delivers additional messages.	Behavioral: No Chatbot Control; In this intervention, participants will see a standard CDC HPV vaccine message only and will not interact with any chatbot.

Outcome Measures

Primary Outcome Measures

1. Attitudes toward HPV vaccination [Immediately after the intervention]

   Participants' attitudes toward HPV vaccination will be measured by seven questions such as ""The HPV vaccine is beneficial for adolescents."

2. Intentions toward HPV vaccination [Immediately after the intervention]

   Participants' intentions toward vaccinating their children against HPV will be measured by three questions such as "I am likely to get my child/children the HPV vaccine."

Secondary Outcome Measures

1. Ratings of the Chatbot [Immediately after the intervention]

   Participants in the chatbot conditions will rate the chatbot on a number of characteristics such as engagingness, relevance, and trustworthiness.

Eligibility Criteria

Criteria

• Ages Eligible for Study: 18 Years and Older
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: Yes

Inclusion Criteria:

• 18 years or older

• Self-identify as Black or African American

• Parents of children under 18 years old

• Access to computer/laptop/mobile device and the Internet

Exclusion Criteria:

• Under 18 years

• Does not self-identify as Black or African American

• Not a parent of at least a child under 18 years old

• No access to computer/laptop/mobile device or the Internet

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	University of Maryland, College Park (Online Survey-Experiment)	College Park	Maryland	United States	20742

Sponsors and Collaborators

• University of Maryland, College Park

Investigators

• Principal Investigator: Xiaoli Nan, University of Maryland, College Park

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: University of Maryland, College Park
• ClinicalTrials.gov Identifier: NCT05959564
• Other Study ID Numbers: 1960782-1
• First Posted: Jul 25, 2023
• Last Update Posted: Jul 25, 2023
• Last Verified: Jul 1, 2023

• Individual Participant Data (IPD) Sharing Statement: Yes
• Plan to Share IPD: Yes
• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No
• Additional relevant MeSH terms: Anus Neoplasms; Penile Neoplasms

Study Results

No Results Posted as of Jul 25, 2023