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Evaluation and Characterisation of Microplastics and Nanoplastics in Joint Synovial Liquid

Sponsor
Universitatea de Medicina si Farmacie Iuliu Hatieganu (Other)
Overall Status
Not yet recruiting
CT.gov ID
NCT05678049
Collaborator
(none)
50
Enrollment
23
Anticipated Duration (Months)

Study Details

Study Description

Brief Summary

The research study aims to evaluate the synovial fluid to highlight the presence of possible micropolymers (micro/nanoplastics) in order to better understand the pathophysiology of joint degenerative processes. For patients with liquid under tension at the joint level, the symptomatology often requires evacuation by puncture under ultrasound guidance. The intervention will be performed only for patients for whom this therapeutic indication exists anyway by their physician.

The investigators want to use this liquid for Microscopic and Spectrophotometric evaluation.

Condition or Disease Intervention/Treatment Phase
  • Diagnostic Test: Synovial fluid analysis

Study Design

Study Type:
Observational
Anticipated Enrollment :
50 participants
Observational Model:
Cohort
Time Perspective:
Prospective
Official Title:
Evaluation and Characterisation of Microplastics and Nanoplastics in Joint Synovial Liquid
Anticipated Study Start Date :
Jan 15, 2023
Anticipated Primary Completion Date :
Dec 15, 2023
Anticipated Study Completion Date :
Dec 15, 2024

Outcome Measures

Primary Outcome Measures

  1. microplastics [immediately after liquid extraction]

    evaluation with spectrophotometry and optic microscopy

  2. nanoplastics [immediately after liquid extraction]

    evaluation with spectrophotometry and optic microscopy

Eligibility Criteria

Criteria

Ages Eligible for Study:
18 Years to 90 Years
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:

  • arthritis of the knee with liquid aspiration recommendation

  • age >18 years

Exclusion Criteria:

--refusal of the patient to participate

-age<18 years

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

  • Universitatea de Medicina si Farmacie Iuliu Hatieganu

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Ciubean Alina Deniza, Director, Universitatea de Medicina si Farmacie Iuliu Hatieganu
ClinicalTrials.gov Identifier:
NCT05678049
Other Study ID Numbers:
  • UMFCluj
First Posted:
Jan 10, 2023
Last Update Posted:
Jan 10, 2023
Last Verified:
Jan 1, 2023
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms:
Arthritis
Osteoarthritis, Knee
Elephantiasis

Study Results

No Results Posted as of Jan 10, 2023