ADDICTALGO: Study of the Characteristics of Chronic Pain in Patients With Addiction

Sponsor
Groupe Hospitalier de Bretagne Sud (Other)
Overall Status
Recruiting
CT.gov ID
NCT05976178
Collaborator
(none)
300
1
22
13.6

Study Details

Study Description

Brief Summary

It is described in the literature a higher prevalence of pain in patients with an addiction but there are few studies describing the pain profile of patients with use disorder.

Pain has a very negative impact on the quality of life of opioid substituted patients. Improving knowledge on this point would make it possible to better guide specific care.

The investigator proposes to conduct a single-center descriptive observational study using questionnaires, without changing the management of patients with chronic pain.

The primary objective of the study is to determine the prevalence of chronic pain in patients with substance addiction hospitalized for addiction treatment.

Condition or Disease Intervention/Treatment Phase

    Detailed Description

    It is described in the literature a higher prevalence of pain in patients with an addiction but there are few studies describing the pain profile of patients with use disorder.

    Pain has a very negative impact on the quality of life of opioid substituted patients. Improving knowledge on this point would make it possible to better guide specific care.

    The investigator proposes to conduct a single-center descriptive observational study using questionnaires, without changing the management of patients with chronic pain. All patients admitted to hospitalization in the addictology department of the Lorient Hospital will be offered participation in the study.

    The primary objective of the study is to determine the prevalence of chronic pain in patients with substance addiction hospitalized for addiction treatment.

    The study will also evaluate the impact on daily activities of the presence of two chronic pathologies: chronic pain and addiction, describe the frequency of the two main psychiatric comorbidities of chronic pain: anxiety and depression, describe the different components of chronic pain in patients with substance addiction, and get information on analgesic medications.

    Study Design

    Study Type:
    Observational
    Anticipated Enrollment :
    300 participants
    Observational Model:
    Cohort
    Time Perspective:
    Prospective
    Official Title:
    Descriptive, Prospective Study of the Characteristics of Chronic Pain in Patients With Addiction to at Least One Substance
    Actual Study Start Date :
    Dec 10, 2022
    Anticipated Primary Completion Date :
    Jun 10, 2024
    Anticipated Study Completion Date :
    Oct 10, 2024

    Outcome Measures

    Primary Outcome Measures

    1. Prevalence of chronic pain in patients with substance addiction hospitalized for addiction treatment. [During the hospitalization, maximum 1 month]

      Percentage of patients presenting with pain for more than three months among patients hospitalized in an addiction service for the management of an addiction

    Secondary Outcome Measures

    1. Pain intensity in the last 24 hours [During the hospitalization, maximum 1 month]

      Results of the Brief Pain Inventory : worst and least of pain in the last 24 hours

    2. Interference of pain on the quality of life [During the hospitalization, maximum 1 month]

      Result of Brief pain inventory on general activity, mood, walking ability, normal work, relations with other people, sleep, enjoyment of life. On a scale from 0 (does not interfere) to 10 (completely interferes)

    3. Localisation of pain [During the hospitalization, maximum 1 month]

      Drawing on a diagram of a human body

    4. Describe the frequency of the two main psychiatric comorbidities of chronic pain: anxiety [During the hospitalization, maximum 1 month]

      Results of the anxiety scale of Hospital Anxiety and Depression scale. Positive if > 8. Minimum 0, maximum 21

    5. Describe the frequency of the two main psychiatric comorbidities of chronic pain: depression [During the hospitalization, maximum 1 month]

      Results of the depression scale of Hospital Anxiety and Depression scale. Positive if > 8. Minimum 0, maximum 21

    6. Describe the prevalence of fibromyalgia among patients with substance addiction [During the hospitalization, maximum 1 month]

      Results of the Fibromyalgia Rapid Screening Tool. Suspicion of fibromyalgia if >5 yes. Maximum 6 yes

    7. Information on analgesics medication [During the hospitalization, maximum 1 month]

      Collection of current analgesic medication taken every day

    8. Describe the prevalence of neuropathic pain among patients with substance addiction [During the hospitalization, maximum 1 month]

      Results of the DN3 (Douleur neuropathique 3). Suspicion of neuropathic pain when > 3/7

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    18 Years and Older
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    No
    Inclusion Criteria:
    • 18 years old

    • Presence of addiction to at least one substance, based on DSM-5 criteria

    • Hospitalized in the addiction service of Lorient Hospital

    • Knowing how to read and write French

    • Not objecting to their participation in the study after informed information

    Exclusion Criteria:
    • Already included during a precedent hospitalization

    • Adults subject to legal protection or deprived of their liberty.

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Groupe Hospitalier Bretagne Sud Lorient France 56100

    Sponsors and Collaborators

    • Groupe Hospitalier de Bretagne Sud

    Investigators

    • Principal Investigator: Alexandre Cauchie, MD, GH Bretagne Sud

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    Responsible Party:
    Alexandre Cauchie, Principal Investigator, Groupe Hospitalier de Bretagne Sud
    ClinicalTrials.gov Identifier:
    NCT05976178
    Other Study ID Numbers:
    • 56LORC_2021_ADDICTALGO
    First Posted:
    Aug 4, 2023
    Last Update Posted:
    Aug 4, 2023
    Last Verified:
    Jul 1, 2023
    Individual Participant Data (IPD) Sharing Statement:
    No
    Plan to Share IPD:
    No
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No
    Additional relevant MeSH terms:

    Study Results

    No Results Posted as of Aug 4, 2023