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CPR: Chest Compression and Cerebral Oxygenation During Cardiopulmonary Resuscitation

Sponsor
Nevsehir Public Hospital (Other)
Overall Status
Completed
CT.gov ID
NCT03062306
Collaborator
(none)
20
Enrollment
1
Location
15
Actual Duration (Months)
1.3
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

In recent years, monitorizations during Cardiopulmonary Resuscitation (CPR) are inadequate to show the sufficiency of cerebral oxygenation. During CPR, insufficient chest compressions have critical importance for neurological results and life quality after the return of spontaneous circulation (ROSC).

Condition or Disease Intervention/Treatment Phase

    Detailed Description

    The Near-Infrared Spectroscopy (NIRS), which is used in measuring the cerebral tissue oxygenation is one of the latest technologies that allow the measurement of brain oxygen saturation. With this study, the issue of whether sufficient cerebral oxygenation is provided during CPR applied to patients that have Cardiac Arrest (CA) will be investigated, and the effect of CPR on the patient prognosis after ROSC will be examined. In this study, the aim is to investigate whether sufficient oxygenation is provided in synchronization with chest compressions during CPR; and to test the regional brain tissue saturation with rSO2 measurement, and the prognosis with Full Outline of UnResponsiveness (FOUR) Score in patients with ROSC.

    Study Design

    Study Type:
    Observational
    Actual Enrollment :
    20 participants
    Observational Model:
    Case-Control
    Time Perspective:
    Prospective
    Official Title:
    Can Sufficient Cerebral Oxygenation be Provided in a Synchronized Manner With Chest Compression During Cardiopulmonary Resuscitation?
    Actual Study Start Date :
    May 31, 2017
    Actual Primary Completion Date :
    Aug 31, 2017
    Actual Study Completion Date :
    Aug 31, 2018

    Outcome Measures

    Primary Outcome Measures

    1. The levels of regional brain tissue oxygen saturation (rSO2) providing with chest compressions during Cardiopulmonary Resuscitation (CPR) [About six month]

      The data will be obtained by using the Near Infrared Spectroscopy (NIRS) Device and will be recorded rSO2 measurement during the resuscitation of the Cardiac Arrest (CA) patients

    Secondary Outcome Measures

    1. Change from baseline in consciousness on Full Outline of UnResponsiveness (FOUR) Score at one week [For a week after ROSC]

      The patient's consciousness will be evaluated by FOUR score in patients with ROSC

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    18 Years and Older
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    No
    Inclusion Criteria:
    1. All patients undergoing cardiac arrest in intensive care unit
    Exclusion Criteria:

    1. Head injury and intracranial bleeding

    2. Cerebral ischemic vascular event

    3. Pulmonary diseases that may affect blood-oxygen levels

    4. Below the age of 18

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Mehmet Akif YAZAR Nevsehir Turkey 50100

    Sponsors and Collaborators

    • Nevsehir Public Hospital

    Investigators

    None specified.

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    Responsible Party:
    Mehmet Akif Yazar, Critical Care Physician, Nevsehir Public Hospital
    ClinicalTrials.gov Identifier:
    NCT03062306
    Other Study ID Numbers:
    • 2016/351
    • Erciyes University
    First Posted:
    Feb 23, 2017
    Last Update Posted:
    Feb 22, 2019
    Last Verified:
    Feb 1, 2019
    Studies a U.S. FDA-regulated Drug Product:
    No
    Studies a U.S. FDA-regulated Device Product:
    No
    Keywords provided by Mehmet Akif Yazar, Critical Care Physician, Nevsehir Public Hospital
    Cerebral Oxygenation
    Cardiopulmonary Resuscitation
    Chest Compression

    Study Results

    No Results Posted as of Feb 22, 2019