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Usefulness of 64 Slice Multi-Detector Computed Tomography as a First Diagnostic Approach in Acute Chest Pain Patients

Sponsor
Seoul National University Bundang Hospital (Other)
Overall Status
Completed
CT.gov ID
NCT00431886
Collaborator
(none)
400
Enrollment
1
Location
20
Duration (Months)
20
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The purpose of this study is to determine the usefulness of 64 slice multi-detector computed tomography as a first diagnostic approach in acute chest pain patients in emergency room

Condition or Disease Intervention/Treatment Phase
  • Procedure: 64 multi-detector computed tomography
 N/A

Detailed Description

We prospectively enrolled the patients with acute chest pain who visited ED. Exclusion criteria were myocardial infarction (MI) with ST elevation, unstable vital sign, uncontrolled arrhythmia, renal dysfunction, hypersensitivity to contrast media and pregnancy. Patients were allocated into 3 categories based on history, physical exam, and electrocardiogram: 1) definite angina with uncertainty of regarding MI (high risk), 2) probable angina (intermediate risk), 3) low likelihood of angina (low risk), and then randomized to either receive MDCT immediately (MDCT group), or not (control). We compared diagnostic accuracy, length of stay in ER, admission rate, and major adverse cardiac events (MACE) and clinical diagnosis in 1 month after discharge from ED.

Study Design

Study Type:
Interventional
Anticipated Enrollment :
400 participants
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Masking:
None (Open Label)
Primary Purpose:
Diagnostic
Official Title:
Usefulness of 64 Slice Multi-Detector Computed Tomography as a First Diagnostic Approach in Acute Chest Pain Patients
Study Start Date :
Apr 1, 2006
Actual Study Completion Date :
Dec 1, 2007

Outcome Measures

Primary Outcome Measures

  1. Admission rate []

  2. Unnecessary admission rate []

Secondary Outcome Measures

  1. Stay time in emergency department []

  2. Diagnostic accuracy []

  3. MACE []

Eligibility Criteria

Criteria

Ages Eligible for Study:
19 Years and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
  • Acute chest pain patient visiting emergency room
Exclusion Criteria:

  • unstable vital sign

  • renal failure

  • ST elevation myocardial infarction

  • uncontrolled arrhythmia

  • hypersensitivity to contrast dye

  • clinically no possibility of angina

Contacts and Locations

Locations

Site City State Country Postal Code
1 Seoul National University Bundang hospital Sungnam-si Kyungkido Korea, Republic of 463-707

Sponsors and Collaborators

  • Seoul National University Bundang Hospital

Investigators

  • Study Director: Huk-Jae Chang, MD, Seoul National University Bundang Hospital

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
, ,
ClinicalTrials.gov Identifier:
NCT00431886
Other Study ID Numbers:
  • B-0603/031-009
First Posted:
Feb 6, 2007
Last Update Posted:
Jun 21, 2011
Last Verified:
Feb 1, 2007
Keywords provided by , ,
Chest pains
Computed tomography
Emergency
Additional relevant MeSH terms:
Chest Pain

Study Results

No Results Posted as of Jun 21, 2011