Comparison Of Dexmedetomidine & Ketamine For Control Of Shivering In Vaginal Hysterectomy Under Spinal Anesthesia
Study Details
Study Description
Brief Summary
comparison of Dexmedetomidine And Ketamine For Control Of Shivering In Vaginal Hysterectomy Proceeded Under Spinal Anesthesia.
Condition or Disease | Intervention/Treatment | Phase |
---|---|---|
Phase 3 |
Detailed Description
In this study the participants aim to Compare Dexmedetomidine And Ketamine For Control Of Shivering In Vaginal Hysterectomy Proceeded Under Spinal Anesthesia regarding efficacy, hamemodynamic stability, outcomes and adverse effects.
Study Design
Arms and Interventions
Arm | Intervention/Treatment |
---|---|
Experimental: Group Dexmedetomidine Group Dexmedetomidine receiving I/V bolus of dexmedetomidine 0.1 mg/kg as a 20 ml solution, followed by 0.04mg/kg/hr infusion till surgery completion |
Drug: Dexmedetomidine
I/V bolus of dexmedetomidine 0.1 mg/kg as a 20 ml solution, followed by 0.04mg/kg/hr infusion
|
Experimental: Group Ketamine Group Ketamine receiving 0.2 mg/kg iv of ketamine diluted to 20 ml followed by 0.1 mg/kg/hr infusion till surgery completion |
Drug: Ketamine
0.2 mg/kg iv of ketamine diluted to 20 ml followed by 0.1 mg/kg/hr infusion
|
Outcome Measures
Primary Outcome Measures
- Change in Shivering grade [Shivering grade of patients will be evaluated every 15 minutes interval after giving the drug till 1hour postoperatively]
Shivering of patients will be grouped into five grades; Grade 0: lack of shivering, Grade I: slight shivering (inconsiderable yet apparent peripheral vasoconstriction), Grade II: medium level shivering (muscular activity in one muscle group only), Grade III: severe shivering (muscular activity in more than one muscle group without generalized shivering), Grade IV: generalized shivering.
Eligibility Criteria
Criteria
Inclusion Criteria:
-
Patients of age 45-55 years requiring vaginal hysterectomy
-
American Society of Anesthesiology (ASA) of Grade I-II
Exclusion Criteria:
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Patients unwilling or non-cooperative for spinal anesthesia
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Patients with uncontrolled hypertension, vascular or coronary disease,
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patients with increased intraocular or intracranial pressure
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Patients with known bleeding and psychiatric disorders
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Patients taking anti platelets drugs.
Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- Hamdard University
Investigators
- Principal Investigator: Nida Shahid, MBBS,FCPS, Hamdard University
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- N0331