Chinese Community Sample of Hierarchical Model of Psychopathology

• Sponsor: Shanghai Mental Health Center (Other)
• Overall Status: Recruiting
• CT.gov ID: NCT06105970
• Collaborator: (none)
• Enrollment: 4,000
• Location: 1
• Anticipated Duration (Months): 49.2
• Patients Per Site Per Month: 81.3

Study Details

Study Description

Brief Summary

By validating Hierarchy Model of psychopathology(HiTOP) in Chinese community samples, this study aims for illumating the problem of diagnostic heterogeneity and high comorbidity within existing psychiatric classification systems in Chinese culture. Concurrently, this study also focuses on exploring trans-diagonostic risk and proctective factors underline HiTOP dimensions.

the main questions it aims to answer are:

1. Explore HiTOP model cultural differences between western culture and eastern culture.

2. Understand the impact of different dimension of adverse childhood experience on HiTOP structure.

3. Investigate the relationship between individual unique psychological variables and psychopathological dimensions.

Participants will receive a detailed survey trying to measure their psychopathology symptoms, adverse childhood experience and psychological variables. This study expects to fallow up participants for 4 years to monitor the symptom changes.

Condition or Disease	Intervention/Treatment	Phase
Mental Health Issue; Adverse Childhood Experience	Other: No intervention

Study Design

• Study Type: Observational
• Anticipated Enrollment: 4000 participants
• Observational Model: Ecologic or Community
• Time Perspective: Cross-Sectional
• Official Title: Chinese Community Sample of Hierarchical Model of Psychopathology : Validation and Analysis of Underline Trans-diagnostic Risk Factors
• Actual Study Start Date: Sep 26, 2023
• Anticipated Primary Completion Date: Nov 1, 2023
• Anticipated Study Completion Date: Nov 1, 2027

Arms and Interventions

Arm	Intervention/Treatment
Community sample Using social media to randomly inviting participants across all regions of China.	Other: No intervention; cross sectional study#no intervention

Outcome Measures

Primary Outcome Measures

1. Chinese version of Hierarchy Model of psychopathology [1 year]

   Constructing the Chinese version of Hierarchy Model of psychopathology. Comparing the differences between Chinese version and western version.

2. Mapping different dimension of adverse childhood experience on Hierarchy Model of psychopathology structure [1 year]

Secondary Outcome Measures

1. Investigate the relationship between individual unique psychological variables and psychopathological dimensions. [4 years]

Eligibility Criteria

Criteria

• Ages Eligible for Study: 18 Years and Older
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: Yes

Inclusion Criteria:

1. Chinese citizens

2. Years of education > =9 years.

3. age >= 18 years old.

Exclusion Criteria:

(1)Subjects who have insufficient self-awareness, and are unable to obtain complete informed consent, such as: schizophrenia, manic episode of bipolar disorder, severe depression.

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Shanghai Mental Health Center	Shanghai		China

Sponsors and Collaborators

• Shanghai Mental Health Center

Investigators

• Principal Investigator: Zhen Wang, PhD, MD, Shanghai Mental Health Center

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: Zhen Wang, vice-president, Shanghai Mental Health Center
• ClinicalTrials.gov Identifier: NCT06105970
• Other Study ID Numbers: HiTOP001
• First Posted: Oct 30, 2023
• Last Update Posted: Oct 30, 2023
• Last Verified: Oct 1, 2023

• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No
• Keywords provided by Zhen Wang, vice-president, Shanghai Mental Health Center: Hierarchical Model of Psychopathology

Study Results

No Results Posted as of Oct 30, 2023