EC_PC_AZSTL: Different Treatments in Chronic Pain Patients.
Study Details
Study Description
Brief Summary
The goal of this observational study is to compare different treatment options in a chronic pain population. The main questions it aims to answer are:
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What is the effectiveness of the different therapy options in the pain center of Sint-Lucas on outcomes related to pain and disability?
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What are predictive factors for the different therapy options in the pain center of Sint-Lucas? Which factors predict improvement in pain related outcomes?
Participant data will be gathered as part of their routine care. They can be advised to 4 different treatment options:
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Consultations with the pain specialist
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Interventions by the pain specialist (infiltrations, denervations)
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Bakster therapy
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Interdisciplinary treatment
Researchers will compare patients with different dominant pain mechanisms to see which treatment are most effective for which dominant pain mechanisms.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Detailed Description
The aim of the present study is to describe the natural flow of the chronic pain patients at the pain center AZ Sint-Lucas. Patients will receive online standardized questionnaires at several fixed timepoints (during and after their therapy trajectory). Fixed follow-up measurements are chosen since each patient receives an individual and different treatment, whereby the end point of the treatment will differ for every patient. These questionnaires will gather demographic data, information about the present dominant pain mechanism, the presence of psychosocial factors, catastrophizing, fear and avoidance, illness perceptions, fatigue and information about therapy success. By processing the data of the questionnaires, knowledge about (1) the amount of patients with a dominant nociplastic pain mechanism at intake, (2) the treatment trajectory for a specific diagnosis, and (3) the prediction of the therapy effect and prognosis will be obtained.
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Chronic pain patients Chronic pain patients with a dominant nociceptive pain mechanism, a dominant neuropathic pain mechanism and a dominant nociplastic pain mechanism. They will receive different treatments: Consultations, Interventions (injections, denervations...), Bakster therapy and interdisciplinary treatment. |
Other: Consultation
Consultation with the pain specialist, which might entail prescrition of medication of vitamins.
Procedure: Interventions
Facet injections, nerve denervations, infiltrations, Qutenza, Spinal Cord Stimulation, Transcutaneous Electrical Nerve Stimulation
Drug: Baxter therapy
Ketamin or Linisol baxter therapy
Behavioral: Interdisciplinary therapy
Interdisciplinary therapy provided by the physiotherapist, psychologist and occupational therapist.
|
Outcome Measures
Primary Outcome Measures
- Change in Pain disability from baseline until 18 months [0 weeks, 4 weeks, 10 weeks, 6 months, 12 months, 18 months]
Pain Disability Index, ranges from zero to 70, with a higher score indicating more pain-related disability
- Change in Pain intensity from baseline until 18 months [0 weeks, 4 weeks, 10 weeks, 6 months, 12 months, 18 months]
Numeric Rating Scale for pain intensity in the past week, ranges from zero to 100, with a higher score indicating a higher pain intensity
- Change in Pain Frequency from baseline until 18 months [0 weeks, 4 weeks, 10 weeks, 6 months, 12 months, 18 months]
Questions
- Change in Functionality from baseline until 18 months [0 weeks, 4 weeks, 10 weeks, 6 months, 12 months, 18 months]
Patient Specific Complaints questionnaire, using a Numeric Rating Scale, ranging from zero to 100, with a higher score indicating a higher amount of functional disability
Secondary Outcome Measures
- Change in Post exertional malaise from baseline until 18 months [0 weeks, 4 weeks, 10 weeks, 6 months, 12 months, 18 months]
Questions based on the criteria for Chronic Fatigue Syndrome.
- Change in Quality of Life from baseline until 18 months [0 weeks, 4 weeks, 10 weeks, 6 months, 12 months, 18 months]
EuroQol - 5D, five questions about health range from one to three with a higher score indicating more difficulties. One question about perceived health ranges from zero to 100 with a higher score indicating better health.
Eligibility Criteria
Criteria
Inclusion Criteria:
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Adults
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Chronic pain patients
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Dutch speaking, or good understanding
Exclusion Criteria:
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Adults unable to give consent
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Adults who do not understand Dutch
Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- University Ghent
Investigators
- Principal Investigator: Jessica Van Oosterwijck, Department of Rehabilitation Sciences, Faculty of Health Sciences, Ghent University, Belgium
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- ONZ-2022-0090
- 2021-39