Spironolactone and Insulin Resistance in Chronic Heart Failure (CHF)
Sponsor
Tottori University Hospital (Other)
Overall Status
Completed
CT.gov ID
NCT00664222
Collaborator
(none)
16
23
Study Details
Study Description
Brief Summary
The purpose of this study is to evaluate the effects of spironolactone and furosemide on insulin resistance in patients with chronic heart failure.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Phase 4 |
Detailed Description
Diuretics is useful in CHF patients. On the other hand, they deteriorate glucose metabolism. Therefore, the purpose of this study is to evaluate the effects of spironolactone and furosemide on insulin resistance in patients with chronic heart failure.
Study Design
Study Type:
Interventional
Actual Enrollment
:
16 participants
Allocation:
Randomized
Intervention Model:
Crossover Assignment
Masking:
Double (Participant, Investigator)
Primary Purpose:
Treatment
Official Title:
Effects of Spironolactone on Insulin Resistance in Patients With Chronic Heart Failure
Study Start Date
:
Jan 1, 2004
Study Completion Date
:
Dec 1, 2005
Outcome Measures
Primary Outcome Measures
- insulin resistance [16 weeks]
Eligibility Criteria
Criteria
Ages Eligible for Study:
N/A
and Older
Sexes Eligible for Study:
All
Inclusion Criteria:
- chronic stable heart failure
Exclusion Criteria:
- renal dysfunction or under treatment with antidiabetic agents
Contacts and Locations
Locations
No locations specified.Sponsors and Collaborators
- Tottori University Hospital
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.Responsible Party:
,
,
ClinicalTrials.gov Identifier:
NCT00664222
Other Study ID Numbers:
- #344.1
First Posted:
Apr 22, 2008
Last Update Posted:
Apr 22, 2008
Last Verified:
Apr 1, 2008
Keywords provided by ,
,
Additional relevant MeSH terms: