Effects of Choice Bundling on Valuation of Delayed Gains and Losses in Cigarette Smokers

Sponsor
Virginia Polytechnic Institute and State University (Other)
Overall Status
Completed
CT.gov ID
NCT05110716
Collaborator
National Cancer Institute (NCI) (NIH), University of Minnesota (Other)
308
1
4
17
551.5

Study Details

Study Description

Brief Summary

The present study will investigate the effects of choice bundling, in which a single choice produces a series of repeating consequences, on valuation of delayed monetary gains and losses in an online panel of cigarette smokers.

Condition or Disease Intervention/Treatment Phase
  • Behavioral: Bundle-size 1
  • Behavioral: Bundle-size 3
  • Behavioral: Bundle-size 9
N/A

Detailed Description

Choice bundling, in which a single choice produces a series of repeating consequences, has been shown to increase valuation of delayed monetary and non-monetary gains. Interventions derived from this manipulation may be an effective method for mitigating the elevated delay discounting rates observed in cigarette smokers. No prior work, however, has investigated whether effects of choice bundling generalize to reward losses. In the present study, an online panel of cigarette smokers, recruited using Ipsos, will complete assessments for either monetary gains or losses (randomly assigned). In Step 1, participants will complete a delay-discounting task to establish Effective Delay 50 (ED50), or the delay required for a monetary outcome to lose half of its value. In Step 2, participants will complete three conditions of an adjusting-amount task, choosing between a smaller, sooner (SS) adjusting amount and a larger, later (LL) fixed amount. The bundle size (i.e., number of consequences) will be manipulated across conditions, where a single choice will produce either 1 (control), 3, or 9 consequences over time (ascending/descending order counterbalanced). The delay to the first LL amount in each condition, as well as the intervals between all additional SS and LL amounts (where applicable), will be set to individual participants' ED50 values from Step 1 to control for differences in discounting of gains and losses.

Study Design

Study Type:
Interventional
Actual Enrollment :
308 participants
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Intervention Model Description:
Participants are randomly assigned to either a gains or losses group and subsequently complete conditions at bundle-sizes 1, 3, and 9 (within-subjects, order counterbalanced).Participants are randomly assigned to either a gains or losses group and subsequently complete conditions at bundle-sizes 1, 3, and 9 (within-subjects, order counterbalanced).
Masking:
Double (Investigator, Outcomes Assessor)
Masking Description:
Data collection and randomization to groups was performed online without the investigators' direct involvement
Primary Purpose:
Basic Science
Official Title:
Effects of Choice Bundling on Valuation of Delayed Gains and Losses in Cigarette Smokers
Actual Study Start Date :
Jul 26, 2021
Actual Primary Completion Date :
Aug 12, 2021
Actual Study Completion Date :
Aug 12, 2021

Arms and Interventions

Arm Intervention/Treatment
Experimental: Gains, Ascending Bundle-Size Order

Participants will complete the choice bundling adjusting-amount task for monetary gains in an ascending order of bundle size.

Behavioral: Bundle-size 1
In this condition, each choice in the adjusting-amount task produces only a single consequence (e.g., lose $900 in 1 year).

Behavioral: Bundle-size 3
In this condition, each choice in the adjusting-amount task produce a series of three consequences over time. o hold total amount constant across conditions, the $900 available in the bundle-size 1 condition will be distributed equally across all consequences in the series. (e.g., lose $300 in 1 year, lose $300 in 2 years, lose $300 in 3 years).

Behavioral: Bundle-size 9
In this condition, each choice in the adjusting-amount task produce a series of nine consequences over time. To hold total amount constant across conditions, the $900 available in the bundle-size 1 condition will be distributed equally across all consequences in the series. (e.g., lose $100 in 1 year, lose $100 in 2 years, lose $100 in 3 years...lose $100 in 9 years).

Experimental: Gains, Descending Bundle-Size Order

Participants will complete the choice bundling adjusting-amount task for monetary gains in a descending order of bundle size.

Behavioral: Bundle-size 1
In this condition, each choice in the adjusting-amount task produces only a single consequence (e.g., lose $900 in 1 year).

Behavioral: Bundle-size 3
In this condition, each choice in the adjusting-amount task produce a series of three consequences over time. o hold total amount constant across conditions, the $900 available in the bundle-size 1 condition will be distributed equally across all consequences in the series. (e.g., lose $300 in 1 year, lose $300 in 2 years, lose $300 in 3 years).

Behavioral: Bundle-size 9
In this condition, each choice in the adjusting-amount task produce a series of nine consequences over time. To hold total amount constant across conditions, the $900 available in the bundle-size 1 condition will be distributed equally across all consequences in the series. (e.g., lose $100 in 1 year, lose $100 in 2 years, lose $100 in 3 years...lose $100 in 9 years).

Experimental: Losses, Ascending Bundle-Size Order

Participants will complete the choice bundling adjusting-amount task for monetary losses in an ascending order of bundle size.

Behavioral: Bundle-size 1
In this condition, each choice in the adjusting-amount task produces only a single consequence (e.g., lose $900 in 1 year).

Behavioral: Bundle-size 3
In this condition, each choice in the adjusting-amount task produce a series of three consequences over time. o hold total amount constant across conditions, the $900 available in the bundle-size 1 condition will be distributed equally across all consequences in the series. (e.g., lose $300 in 1 year, lose $300 in 2 years, lose $300 in 3 years).

Behavioral: Bundle-size 9
In this condition, each choice in the adjusting-amount task produce a series of nine consequences over time. To hold total amount constant across conditions, the $900 available in the bundle-size 1 condition will be distributed equally across all consequences in the series. (e.g., lose $100 in 1 year, lose $100 in 2 years, lose $100 in 3 years...lose $100 in 9 years).

Experimental: Losses, Descending Bundle-Size Order

Participants will complete the choice bundling adjusting-amount task for monetary losses in an ascending order of bundle size.

Behavioral: Bundle-size 1
In this condition, each choice in the adjusting-amount task produces only a single consequence (e.g., lose $900 in 1 year).

Behavioral: Bundle-size 3
In this condition, each choice in the adjusting-amount task produce a series of three consequences over time. o hold total amount constant across conditions, the $900 available in the bundle-size 1 condition will be distributed equally across all consequences in the series. (e.g., lose $300 in 1 year, lose $300 in 2 years, lose $300 in 3 years).

Behavioral: Bundle-size 9
In this condition, each choice in the adjusting-amount task produce a series of nine consequences over time. To hold total amount constant across conditions, the $900 available in the bundle-size 1 condition will be distributed equally across all consequences in the series. (e.g., lose $100 in 1 year, lose $100 in 2 years, lose $100 in 3 years...lose $100 in 9 years).

Outcome Measures

Primary Outcome Measures

  1. Indifference points [1 day (same session)]

    Participants complete three conditions of the adjusting-amount task (one at each bundle size), in which they choose between a larger, delayed amount ($900) and a smaller, immediate amount. Across trials, the smaller amount titrates until reaching an indifference point. This indifference point provides an index of the value of the larger option. For example, an indifference point of $300 indicates the larger, delayed amount as been discounted by two thirds. Higher values reflect less delay discounting.

Eligibility Criteria

Criteria

Ages Eligible for Study:
21 Years and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
  • currently smoke at least 10 cigarettes per day

  • have smoked at least 100 cigarettes (lifetime), and

  • are 21 years of age or older.

Exclusion Criteria:
  • Inaccurate identification of usual brand cigarette's as menthol or non-menthol

Contacts and Locations

Locations

Site City State Country Postal Code
1 Fralin Biomedical Research Institute at VTC Roanoke Virginia United States 24016

Sponsors and Collaborators

  • Virginia Polytechnic Institute and State University
  • National Cancer Institute (NCI)
  • University of Minnesota

Investigators

  • Principal Investigator: Warren K Bickel, PhD, Virginia Polytechnic Institute and State University

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Warren K. Bickel, Professor, Virginia Polytechnic Institute and State University
ClinicalTrials.gov Identifier:
NCT05110716
Other Study ID Numbers:
  • 20-827
  • 5P01CA217806
First Posted:
Nov 8, 2021
Last Update Posted:
Nov 8, 2021
Last Verified:
Oct 1, 2021
Individual Participant Data (IPD) Sharing Statement:
Yes
Plan to Share IPD:
Yes
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Keywords provided by Warren K. Bickel, Professor, Virginia Polytechnic Institute and State University

Study Results

No Results Posted as of Nov 8, 2021