Evaluation of Clinical Decisions and Assessment of Those at Risk of Primary Angle Closure by Community Optometrists

Sponsor
Moorfields Eye Hospital NHS Foundation Trust (Other)
Overall Status
Not yet recruiting
CT.gov ID
NCT05543889
Collaborator
(none)
150
12

Study Details

Study Description

Brief Summary

Increases in the aging population has resulted in increased demand for glaucoma services. Glaucoma is a disease that if untreated, can lead to blindness. This increase and need for long term treatment with monitoring have resulted in a significant demand in the hospital eye service (HES). Many departments are now facing a considerable backlog of outpatient appointments and it's essential that these appointments are reserved for patients who are at risk of glaucoma blindness.

Primary angle closure (PAC) glaucoma is a type of glaucoma, where the drainage route for the fluid inside the eye (known as the angle) is narrowed or blocked. It has been recently identified that approximately half of patients referred into the HES for a suspect narrow angle for further investigation are healthy and are immediately discharged. The exact reasons for these findings are unknown.

This project will investigate clinical decisions by community optometrists who account for the majority of PAC referrals into the HES, as well as assessing their ability to evaluate those at risk of PAC. This project will also examine whether clinical agreement could be improved by providing an educational package.

A clinical image database of angles will be acquired from glaucoma patients attending Moorfields Eye Hospital. A learning package discussing angle closure referral will also be developed. Community optometrists will be invited to complete a questionnaire on their clinical decision making. This will be followed by the vignette assessment, learning package and re-assessment.

If this educational package and/or any other identifiers are found to improve agreement levels, this could reduce the number of referrals and enable community monitoring of those at low risk of developing PAC glaucoma in their lifetime.

Condition or Disease Intervention/Treatment Phase
  • Other: Educational package

Study Design

Study Type:
Observational
Anticipated Enrollment :
150 participants
Observational Model:
Cohort
Time Perspective:
Prospective
Official Title:
Evaluation of Clinical Decisions and Assessment of Those at Risk of Primary Angle Closure by Community Optometrists
Anticipated Study Start Date :
Oct 1, 2022
Anticipated Primary Completion Date :
Sep 30, 2023
Anticipated Study Completion Date :
Sep 30, 2023

Arms and Interventions

Arm Intervention/Treatment
Patients

100 patient participants will be recruited for limbal anterior chamber depth image capture. These images will be used to develop the clinical vignette database

Optometrists

50 optometrists will be recruited to undertake the clinical vignette assessment

Other: Educational package
Online learning package that will discuss the van Herick technique, grading, accuracy and information and discusses the current guidelines for primary angle closure suspect referral.

Outcome Measures

Primary Outcome Measures

  1. Agreement of community optometrists on measuring Limbal anterior chamber depth [12 months]

    Levels of agreement and precision of optometrist observers before and after intervention of online educational package in assessment of Limbal anterior chamber depth as a surrogate measure of angle width. Agreement will be measured via an online assessment vignette assessment package. Weighted Kappa statistic and levels agreement will be the outcome measures

Secondary Outcome Measures

  1. Qualitative outcome measures from optometrists [12 months]

    Questionnaire based outcomes capturing data around current practice, qualifications and training, knowledge and resources with regards to angle closure diagnosis and referral

  2. Qualitative outcome measures from patients [12 months]

    Experience of testing, time taken and costs of travel to test site and amount of time spent

Eligibility Criteria

Criteria

Ages Eligible for Study:
18 Years and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:

New patients attending the glaucoma clinic at Moorfields Eye Hospital

Exclusion Criteria:
  • They cannot be examined using a table mounted slit lamp due to physical limitations or have gross nystagmus.

  • Unable to consent

  • If they are unable to communicate in English and there is no available interpreter that meets requirements set out by Moorfields standard operating policies for patients

  • Under 18 years old

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

  • Moorfields Eye Hospital NHS Foundation Trust

Investigators

  • Principal Investigator: Anish Jindal, Moorfields Eye Hospital NHS Foundation Trust/UCL

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Moorfields Eye Hospital NHS Foundation Trust
ClinicalTrials.gov Identifier:
NCT05543889
Other Study ID Numbers:
  • JINA1001
First Posted:
Sep 16, 2022
Last Update Posted:
Sep 16, 2022
Last Verified:
Sep 1, 2022
Individual Participant Data (IPD) Sharing Statement:
No
Plan to Share IPD:
No
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Keywords provided by Moorfields Eye Hospital NHS Foundation Trust
Additional relevant MeSH terms:

Study Results

No Results Posted as of Sep 16, 2022