Clinical Features, Outcomes, and Therapeutics of Pregnancy-Related Aortic Dissection
Sponsor
Nanjing Medical University (Other)
Overall Status
Completed
CT.gov ID
NCT05501145
Collaborator
Beijing Anzhen Hospital (Other), Shanghai Zhongshan Hospital (Other), Guangdong Province Hospital (Other)
75
4
6.9
18.8
2.7
Study Details
Study Description
Brief Summary
Aortic dissection in pregnancy represents a lethal risk to both the mother and fetus, it has yet to yield the optimal therapeutic strategy. The aim of this study was to characterize the clinical features and outcomes in women with pregnancy-related acute aortic dissection, and to suggest therapeutic guidelines.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Study Design
Study Type:
Observational
Actual Enrollment
:
75 participants
Observational Model:
Cohort
Time Perspective:
Retrospective
Official Title:
Clinical Features, Outcomes, and Therapeutics of Ppregnancy-related Aortic Dissection
Actual Study Start Date
:
Jan 1, 2022
Actual Primary Completion Date
:
Jul 31, 2022
Actual Study Completion Date
:
Jul 31, 2022
Outcome Measures
Primary Outcome Measures
- 30-day mortality [30 days after surgery]
Eligibility Criteria
Criteria
Ages Eligible for Study:
18 Years
to 45 Years
Sexes Eligible for Study:
Female
Accepts Healthy Volunteers:
No
Inclusion Criteria:
- Women who presented with aortic dissection during pregnancy or post partum ≤12 weeks.
Exclusion Criteria:
- Loss of surgical information.
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Beijing Anzhen Hospital | Beijing | China | 10029 | |
| 2 | Department of Obstetrics and Gynecology, Guangdong Provincial People's Hospital | Guangzhou | China | ||
| 3 | Department of Cardiac Surgery, Affiliated Hospital of Qingdao University | Qingdao | China | ||
| 4 | Department of Obstetrics and Gynecology, Zhongshan Hospital | Shanghai | China |
Sponsors and Collaborators
- Nanjing Medical University
- Beijing Anzhen Hospital
- Shanghai Zhongshan Hospital
- Guangdong Province Hospital
Investigators
- Study Chair: Hong-jia Zhang, MD, Beijing Anzhen Hospital
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.Responsible Party:
Hong Liu,
Principal Investigator of Cardiovascular Surgery,
Nanjing Medical University
ClinicalTrials.gov Identifier:
NCT05501145
Other Study ID Numbers:
- 5A Plan VII
First Posted:
Aug 15, 2022
Last Update Posted:
Aug 15, 2022
Last Verified:
Aug 1, 2022
Individual Participant Data (IPD) Sharing Statement:
Undecided
Plan to Share IPD:
Undecided
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms: