Clinical Outcome of Surgical Treatment for Osteochondral Lesions of the Talus

Sponsor

Assiut University (Other)

Overall Status

Not yet recruiting

CT.gov ID

NCT05476692

Collaborator

(none)

Enrollment

Anticipated Duration (Months)

Study Details

Study Description

Brief Summary

Assess clinical and radiological outcome of the various surgical techniques for treatment of osteochondral lesions of the talus

Condition or Disease	Intervention/Treatment	Phase
Osteochondral Lesion of Talus	Other: AOFAS score and VAS

Detailed Description

Osteochondritis dissecans (OCD) of the talus is a subchondral bone pathology that presents as an osteochondral lesion of the talar dome with consequent articular cartilage abnormalities. Osteochondral lesions of the talus (OLT) are frequent after acute ankle trauma. The natural history of the OLT remains unclear due to paucity of longitudinal follow-up studies. Various treatment strategies have been described for OLT, including conservative treatment and operative treatment However, the current literature does not allow firm evidence-based recommendations concerning the treatment to be established ; Microfracture is the most common reparative surgery for osteochondral lesions of the talus (OLTs). While shown to be effective in short- to midterm outcomes, the fibrocartilage that microfracture produces is both biomechanically and biologically inferior to that of native hyaline cartilage and is susceptible to possible deterioration over time following repair . Arthroscopic debridement (AD) for the osteochondral lesions of the talar dome (OLT) was widely documented in the nineties with satisfactory results. However, in modern treatment algorithms, its role is not described. A frequently used instrument for assessing outcome after ankle and hindfoot injuries is the American Orthopaedic Foot and Ankle Society (AOFAS) Ankle-Hindfoot Score .

Study Design

Study Type:

Observational

Anticipated Enrollment :

40 participants

Observational Model:

Cohort

Time Perspective:

Prospective

Official Title:

Clinical Outcome of Surgical Treatment for Osteochondral Lesions of the Talus

Anticipated Study Start Date :

Oct 1, 2022

Anticipated Primary Completion Date :

Oct 1, 2023

Anticipated Study Completion Date :

Nov 1, 2023

Outcome Measures

Primary Outcome Measures

clinical outcome of the various surgical techniques for treatment of osteochondral lesions of the talus [1 year]
clinical outcome of the various surgical techniques for treatment of osteochondral lesions of the talus , Clinical outcome by the AOFAS score ( American Orthopaedic Foot and Ankle Society), the higher score means the better outcome and the lower score means the worse outcome

Eligibility Criteria

Criteria

Ages Eligible for Study:

15 Years to 60 Years

Sexes Eligible for Study:

All

Inclusion Criteria:

Age from 15 to 60 years old.
Traumatic and degenerative etiology.
without ankle deformity.
No inflammatory arthritis.
Absent or corrected ligamentous instability

Exclusion Criteria:

Older than 60 years old and younger than 15 years old.
Charcot ankle.
Vascular injury.

Contacts and Locations

Locations

No locations specified.

Sponsors and Collaborators

Assiut University

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Additional Information:

Publications

None provided.

Responsible Party:

Mena Magdy Fahmy Dawood, Principal Investigator, Assiut University

ClinicalTrials.gov Identifier:

NCT05476692

Other Study ID Numbers:

OCD of the talus

First Posted:

Jul 27, 2022

Last Update Posted:

Jul 27, 2022

Last Verified:

Jul 1, 2022

Studies a U.S. FDA-regulated Drug Product:

Studies a U.S. FDA-regulated Device Product:

Study Results

No Results Posted as of Jul 27, 2022