Clinical & Pathological Studies of Upper Gastrointestinal Carcinoma

• Sponsor: Stanford University (Other)
• Overall Status: Recruiting
• CT.gov ID: NCT01048281
• Collaborator: National Institutes of Health (NIH) (NIH)
• Enrollment: 100
• Location: 1
• Duration (Months): 1157
• Patients Per Site Per Month: 0.1

Study Details

Study Description

Brief Summary

Our research of the biology of upper gastrointestinal cancers involves the study of tissue samples and cells from biopsies of persons with gastric or esophageal cancer or blood samples from upper gastrointestinal cancer patients and persons at high inherited risk for these cancers. We hope to learn the role genes and proteins play in the development of gastric and esophageal cancer.

Condition or Disease	Intervention/Treatment	Phase
Stomach Cancer; Gastro-Esophageal(GE) Junction Cancer; Gastric (Stomach) Cancer; Esophageal Cancer; Gastrointestinal Stromal Tumor (GIST)	Procedure: Blood draw; Procedure: Tissue tumor biopsy

Study Design

• Study Type: Observational
• Anticipated Enrollment: 100 participants
• Observational Model: Cohort
• Time Perspective: Prospective
• Official Title: Clinical & Pathological Studies of Upper Gastrointestinal Carcinoma
• Study Start Date: Aug 1, 2002
• Anticipated Primary Completion Date: Jan 1, 2099
• Anticipated Study Completion Date: Jan 1, 2099

Outcome Measures

Primary Outcome Measures

1. p53 activity by routine pathologic analysis [time of collection]

2. NER activity by routine pathologic analysis [time of collection]

Eligibility Criteria

Criteria

• Ages Eligible for Study: 18 Years and Older
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: No

Inclusion Criteria:

1. Over 18

2. Diagnosed with gastric or esophageal cancer OR at an increased hereditary risk for upper GI cancer

Exclusion Criteria:

1. Under 18

2. No family or personal history of gastric or esophageal cancer

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Stanford University School of Medicine	Stanford	California	United States	94305

Sponsors and Collaborators

• Stanford University
• National Institutes of Health (NIH)

Investigators

• Principal Investigator: James M Ford, Stanford University

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: Stanford University
• ClinicalTrials.gov Identifier: NCT01048281
• Other Study ID Numbers: GIUPR0001; 76274; CA109190; SU-11022007-787
• First Posted: Jan 13, 2010
• Last Update Posted: Aug 2, 2021
• Last Verified: Jul 1, 2021

• Studies a U.S. FDA-regulated Drug Product: No
• Studies a U.S. FDA-regulated Device Product: No
• Additional relevant MeSH terms: Gastrointestinal Stromal Tumors; Stomach Neoplasms

Study Results

No Results Posted as of Aug 2, 2021