Clinical Related Study on Surgical Treatment of Knee Joint Meniscus Injury

Sponsor
Peking University Third Hospital (Other)
Overall Status
Recruiting
CT.gov ID
NCT04962555
Collaborator
(none)
8,778
1
76
115.5

Study Details

Study Description

Brief Summary

Through the analysis of the data of 8094 patients with knee meniscus injury before December 31, 2008 and more patients with partial meniscus resection, subtotal resection and total resection, we can understand the gender difference and ratio of medial and lateral meniscus injuries. Differences, differences in locations, differences in tearing methods, differences in surgical methods, and the course of the disease affect the meniscus injury and surgical methods, and further affect the patient's knee degeneration imaging, accompanying cartilage injury, knee osteoarthritis, Partial resection, subtotal resection and meniscus regeneration after total resection, imaging and secondary arthroscopic exploration (Second-Look) were studied.

Condition or Disease Intervention/Treatment Phase
  • Procedure: Meniscus Suture
  • Procedure: Partial meniscus resection
  • Procedure: Subtotal meniscus resection
  • Procedure: Complete meniscectomy

Detailed Description

Through the data of 8094 patients with knee meniscus injury who underwent surgery at the Institute of Sports Medicine of the Third Hospital of Beijing Medical University before December 31, 2008, and the patients who underwent meniscus suture, partial resection, subtotal resection, and total resection. Analyze and understand the influence of gender difference, ratio difference, position difference, tearing method difference, surgical method difference and disease course on the meniscus injury situation and operation method of the internal and lateral meniscus injury. Observation and research will also be conducted on reports of knee cartilage injury, knee osteoarthritis, and meniscus regeneration after partial meniscus resection, subtotal resection and total resection.

Study Design

Study Type:
Observational
Anticipated Enrollment :
8778 participants
Observational Model:
Cohort
Time Perspective:
Retrospective
Official Title:
Clinical Related Study on Surgical Treatment of Knee Joint Meniscus Injury
Actual Study Start Date :
Aug 1, 2016
Anticipated Primary Completion Date :
Oct 1, 2022
Anticipated Study Completion Date :
Dec 1, 2022

Arms and Interventions

Arm Intervention/Treatment
Meniscus Suture

The patient underwent meniscus suture surgery

Procedure: Meniscus Suture
Patients with knee joint meniscus injury undergoing meniscus suture

Partial meniscus resection

The patient underwent partial meniscus resection

Procedure: Partial meniscus resection
Patients with knee joint meniscus injury undergoing partial meniscus resection

Subtotal meniscus resection

The patient underwent Subtotal meniscus resection

Procedure: Subtotal meniscus resection
Patients with knee joint meniscus injury undergoing subtotal meniscus resection

Complete meniscectomy

The patient underwent complete meniscectomy

Procedure: Complete meniscectomy
Patients with knee joint meniscus injury undergoing complete meniscectomy

Outcome Measures

Primary Outcome Measures

  1. Meniscus injury site [During operation]

    Observe the meniscus injury site during the operation, which is divided into: medial and lateral anterior horn, medial and lateral body, medial and lateral posterior horn, medial and lateral disc.

  2. Types of Meniscus Injury [During operation]

    The types of meniscus injuries were observed during the operation, which were divided into longitudinal fissure, oblique fissure, spallation, radial fissure, and barrel shank tear.

  3. Meniscus surgery method [During operation]

    Meniscus surgery methods include: partial resection, subtotal resection, total resection, and suture.

  4. Cartilage damage [During operation]

    The cartilage damage is evaluated as yes or no, where the cartilage surface is smooth and complete is defined as no, and the rest is defined as yes.

  5. Cartilage damage [7 years after surgery]

    Second-look after operation to observe whether the cartilage is damaged. The cartilage damage is evaluated as yes or no, where the cartilage surface is smooth and complete is defined as no, and the rest is defined as yes.

  6. Meniscus regeneration [7 years after surgery]

    Second-look after operation to observe whether the meniscus is regenerating. The Meniscus regeneration is evaluated as yes or no, in which the meniscus shape is complete and no tear is defined as yes, and other conditions are defined as no.

Eligibility Criteria

Criteria

Ages Eligible for Study:
N/A and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:

Before December 31, 2008, patients who underwent surgery for meniscus injury in this institute and patients who underwent meniscus suture, partial resection, subtotal resection, and total resection.

Exclusion Criteria:

Contacts and Locations

Locations

Site City State Country Postal Code
1 Institute of Sports Medicine, Peking University Third Hospital Beijing Beijing China 100191

Sponsors and Collaborators

  • Peking University Third Hospital

Investigators

  • Study Chair: Jia-kuo Yu, Prof., Peking University Third Hospital

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
Peking University Third Hospital
ClinicalTrials.gov Identifier:
NCT04962555
Other Study ID Numbers:
  • IRB00006761-2015159
First Posted:
Jul 15, 2021
Last Update Posted:
Jul 15, 2021
Last Verified:
Jun 1, 2021
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Additional relevant MeSH terms:

Study Results

No Results Posted as of Jul 15, 2021