Clinical Research of H3F3AK27M in Spinal Glioma and Its Impact on TMZ Chemoradiotherapy
Sponsor
Southern Medical University, China (Other)
Overall Status
Unknown status
CT.gov ID
NCT03668522
Collaborator
(none)
60
1
16
3.8
Study Details
Study Description
Brief Summary
H3F3AK27M may be a feature of primary spinal cord glioma and affect the outcome and prognosis of TMZ chemoradiotherapy.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Study Design
Study Type:
Observational
Anticipated Enrollment
:
60 participants
Observational Model:
Case-Only
Time Perspective:
Cross-Sectional
Official Title:
Clinical Research of the Molecular Phenotype Distribution of H3F3AK27M in Spinal Glioma and Its Impact on TMZ Chemoradiotherapy
Anticipated Study Start Date
:
Sep 1, 2018
Anticipated Primary Completion Date
:
Jan 1, 2020
Anticipated Study Completion Date
:
Jan 1, 2020
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| children age<=17 |
Other: Genetic testing
To determine whether H3F3AK27M exist in spinal glioma
|
| adult age>17 |
Other: Genetic testing
To determine whether H3F3AK27M exist in spinal glioma
|
Outcome Measures
Primary Outcome Measures
- positive [through study completion, an average of 1 year]
positive of H3F3AK27M
Eligibility Criteria
Criteria
Ages Eligible for Study:
N/A
and Older
Sexes Eligible for Study:
All
Accepts Healthy Volunteers:
No
Inclusion Criteria:
- Surgical treatment and pathological confirmation of spinal glioma in our department and is the first case without any treatment before operation.
Exclusion Criteria:
- The tumor is recurrent or has been treated before operation.
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Nan fang hospital, Southern medical university | Guangzhou | Guangdong | China | 510515 |
Sponsors and Collaborators
- Southern Medical University, China
Investigators
- Study Chair: Lu Yuntao, M.D., Ph.D, Nanfang Hospital Neurosurgery Department
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.Responsible Party:
Yuntao Lu,
adjunct professor,
Southern Medical University, China
ClinicalTrials.gov Identifier:
NCT03668522
Other Study ID Numbers:
- SouthernMUC Neurospine-1
First Posted:
Sep 12, 2018
Last Update Posted:
Sep 12, 2018
Last Verified:
Sep 1, 2018
Individual Participant Data (IPD) Sharing Statement:
Undecided
Plan to Share IPD:
Undecided
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Keywords provided by Yuntao Lu,
adjunct professor,
Southern Medical University, China
Additional relevant MeSH terms: