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Coagulation Parameters During Pregnancy in Amniotic Fluid

Sponsor
Rambam Health Care Campus (Other)
Overall Status
Unknown status
CT.gov ID
NCT00458666
Collaborator
(none)
170
Enrollment
1
Location

Study Details

Study Description

Brief Summary

Amniotic fluid embolism is a rare devastating thromboembolic event, which is probably caused by the entrance of amniotic fluid (AF) to the maternal circulation. While AF contains coagulation activators, their role during pregnancy has not been elucidated. The current study aimed to evaluate coagulation parameters in AF during human pregnancy.

Condition or Disease Intervention/Treatment Phase

    Detailed Description

    Amniotic fluid embolism is a rare devastating thromboembolic event, which is probably caused by the entrance of amniotic fluid (AF) to the maternal circulation. While AF contains coagulation activators, their role during pregnancy has not been elucidated. The current study aimed to evaluate coagulation parameters in AF during human pregnancy.

    Study Design

    Study Type:
    Observational
    Time Perspective:
    Prospective
    Official Title:
    Coagulation Parameters During Pregnancy in Amniotic Fluid
    Study Start Date :
    Jun 1, 2006

    Outcome Measures

    Primary Outcome Measures

      Eligibility Criteria

      Criteria

      Ages Eligible for Study:
      18 Years to 40 Years
      Sexes Eligible for Study:
      Female
      Accepts Healthy Volunteers:
      Yes
      Inclusion Criteria:
      • Women undergoing amniocentesis during 15-35 weeks of gestation.
      Exclusion Criteria:

      • A history of venous thromboembolism

      • Systemic disease i.e.; diabetes, hypertension, hypo or hyper-thyroidism,

      • Anticoagulant treatment

      • Abnormal embryo

      Contacts and Locations

      Locations

      Site City State Country Postal Code
      1 Dept of Obstetrics and Gynecology, Rambam-Health Care Campus Haifa Israel

      Sponsors and Collaborators

      • Rambam Health Care Campus

      Investigators

      • Principal Investigator: Benjamin Brenner, M.D, Rambam Health Care Campus
      • Study Chair: Arie Drugan, M.D, Rambam Health Care Campus

      Study Documents (Full-Text)

      None provided.

      More Information

      Publications

      None provided.
      Responsible Party:
      , ,
      ClinicalTrials.gov Identifier:
      NCT00458666
      Other Study ID Numbers:
      • CoagulationAmnioticFluid_CTIL
      First Posted:
      Apr 11, 2007
      Last Update Posted:
      Apr 11, 2007
      Last Verified:
      Mar 1, 2007
      Keywords provided by , ,
      Amniotic fluid
      D-dimer
      coagulation
      factor X activation

      Study Results

      No Results Posted as of Apr 11, 2007