Prize Contingency Management for Cocaine-Dependent Methadone Patients
Study Details
Study Description
Brief Summary
The investigators will randomize 300 cocaine-dependent methadone patients to 1 of 6 conditions: (a) a control group, (b) a contingency management condition that arranges a 100% probability of winning a prize with each draw and has 3 prize categories, (c) a contingency management condition that arranges a 31% probability of winning and has 3 prize categories, (d) a contingency management condition that arranges a 100% probability of winning and has 7 prize categories, (e) a contingency management condition that arranges a 31% probability of winning and has 7 prize categories, or (f) usual prize contingency management with a 50% probability of winning from 3 prize categories. Magnitudes of reinforcement will be identical across conditions, but lower overall probability conditions arrange for greater chances of winning larger magnitude prizes. The investigators expect that the new contingency management conditions will reduce cocaine use relative to the control condition, that 31% probability conditions will decrease drug use relative to 100% conditions, and that 7-prize category conditions will reduce drug use compared to 3-prize category conditions. In addition, the 31%/7-category condition is expected to be most efficacious. Results will be instrumental for further developing prize contingency management to improve outcomes of cocaine-dependent methadone patients.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
N/A |
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| No Intervention: Treatment Group A Standard Care |
|
| Experimental: Treatment Group B 100% probability of winning a prize with each draw and has 3 prize categories |
Behavioral: prize contingency management
Participants earn the chance to win prizes for the targeted behavior, cocaine abstinence.
|
| Experimental: Treatment Group C 31% probability of winning and has 3 prize categories |
Behavioral: prize contingency management
Participants earn the chance to win prizes for the targeted behavior, cocaine abstinence.
|
| Experimental: Treatment Group D 100% probability of winning and has 7 prize categories |
Behavioral: prize contingency management
Participants earn the chance to win prizes for the targeted behavior, cocaine abstinence.
|
| Experimental: Treatment Group E 31% probability of winning and has 7 prize categories |
Behavioral: prize contingency management
Participants earn the chance to win prizes for the targeted behavior, cocaine abstinence.
|
| Experimental: Treatment Group F usual prize contingency management with a 50% probability of winning from 3 prize categories |
Behavioral: prize contingency management
Participants earn the chance to win prizes for the targeted behavior, cocaine abstinence.
|
Outcome Measures
Primary Outcome Measures
- longest continuous period of cocaine abstinence [three months]
Eligibility Criteria
Criteria
Inclusion Criteria:
-
age > 18 years
-
current DSM-IV diagnosis of cocaine dependence
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enrolled at the clinic for >3 months
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on a stable dose of methadone (no changes) for >1 month and not requesting a dose alteration
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submitted >1 clinic cocaine positive sample in the last 6 months
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English speaking
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pass a quiz related to understanding the informed consent form
Exclusion Criteria:
-
serious, uncontrolled psychiatric illness
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significant cognitive impairment
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in recovery from pathological gambling
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | University of Connecticut Health Center | Farmington | Connecticut | United States | 06030 |
Sponsors and Collaborators
- UConn Health
- National Institute on Drug Abuse (NIDA)
Investigators
- Principal Investigator: Sheila M Alessi, Ph.D., UConn Health
Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- 10-256-2
- R01DA013444