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Cognitive and Functional Status and Dialysis Outcomes in Older Hemodialysis Patients

Sponsor
University of Chicago (Other)
Overall Status
Terminated
CT.gov ID
NCT00739843
Collaborator
(none)
55
Enrollment
1
Location
34
Duration (Months)
1.6
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The purpose of this study is to estimate how quickly cognitive status and functional status in older patients on hemodialysis declines.

Condition or Disease Intervention/Treatment Phase

    Detailed Description

    Dialysis outcome measures, which predict morbidity and mortality of younger patients on renal replacement therapy, such as dialysis clearance, do not correlate with survival of the elderly patients on hemodialysis. Survival of older patients on hemodialysis is significantly worse when compared to that of the younger patients. Conditions commonly affecting older adults, such as functional decline, cognitive impairment, depression and declining quality of life have not been well studied in hemodialysis population. There may be an important relationship between these measurements and outcomes in older dialysis patients. Institution of appropriate age-specific interventions could result in improved health status and mortality of older patients on hemodialysis. Our broad objective is to better understand global functioning of the elderly dialysis patients and its possible impact on dialysis outcomes in attempt to improve health care of the older patients receiving hemodialysis.

    Study Design

    Study Type:
    Observational
    Actual Enrollment :
    55 participants
    Observational Model:
    Cohort
    Time Perspective:
    Prospective
    Official Title:
    Cognitive and Functional Status and Dialysis Outcomes in Older Hemodialysis Patients
    Study Start Date :
    Nov 1, 2007
    Actual Primary Completion Date :
    Sep 1, 2010
    Actual Study Completion Date :
    Sep 1, 2010

    Outcome Measures

    Primary Outcome Measures

      Eligibility Criteria

      Criteria

      Ages Eligible for Study:
      60 Years and Older
      Sexes Eligible for Study:
      All
      Accepts Healthy Volunteers:
      No
      Inclusion Criteria:
      • Prevalent and incident hemodialysis patients over the age of 60, receiving hemodialysis treatments at the University of Chicago outpatient dialysis program.
      Exclusion Criteria:
      • Patients 59 and younger, and patients with the following medical conditions: malignancies currently requiring chemotherapy or radiation therapy, severe heart failure (NYHA class IV), known HIV infection, or currently active hepatic encephalopathy.

      Contacts and Locations

      Locations

      Site City State Country Postal Code
      1 University of Chicago Chronic Hemodialysis Centers Chicago Illinois United States 60617

      Sponsors and Collaborators

      • University of Chicago

      Investigators

      • Principal Investigator: Nicole Stankus, MD, MSc, University of Chicago

      Study Documents (Full-Text)

      None provided.

      More Information

      Publications

      None provided.
      Responsible Party:
      University of Chicago
      ClinicalTrials.gov Identifier:
      NCT00739843
      Other Study ID Numbers:
      • 15813B
      First Posted:
      Aug 22, 2008
      Last Update Posted:
      Nov 1, 2016
      Last Verified:
      Oct 1, 2016
      Keywords provided by University of Chicago
      Dementia,
      Cognitive Disorders,
      Hemodialysis
      Additional relevant MeSH terms:
      Dementia
      Kidney Failure, Chronic

      Study Results

      No Results Posted as of Nov 1, 2016