A Cohort Study of Chronic Cardiovascular Diseases

Sponsor

Peking University First Hospital (Other)

Overall Status

Recruiting

CT.gov ID

NCT04996342

Collaborator

(none)

10,000

Enrollment

Location

55.6

Anticipated Duration (Months)

180

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

This prospective cohort study aims to establish cohorts of patients with chronic cardiovascular disease, including refractory and secondary hypertension, coronary heart disease, atrial fibrillation, ventricular arrhythmias, structural heart disease, pulmonary hypertension, heart failure and rare diseases of the cardiovascular system, and patients with implantations of cardiac pacemaker, in order to dynamically describe the population characteristics, diagnosis and treatment status and long-term prognosis and analyze the factors affecting the choice of treatment plan, long-term management quality and clinical prognosis of these patients.

Condition or Disease	Intervention/Treatment	Phase
Cardiovascular Diseases Cohort Studies

Study Design

Study Type:

Observational

Anticipated Enrollment :

10000 participants

Observational Model:

Cohort

Time Perspective:

Prospective

Official Title:

A Cohort Study of Chronic Cardiovascular Diseases in the Department of Cardiology, Peking University First Hospital

Actual Study Start Date :

Apr 15, 2021

Anticipated Primary Completion Date :

Dec 1, 2025

Anticipated Study Completion Date :

Dec 1, 2025

Outcome Measures

Primary Outcome Measures

Major Adverse Cardiovascular Events [5 year]
Time to the first occurence of Any cause death, myocardial infarction, or Stroke

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

This study includes 9 disease-specific cohorts. The specific inclusion and exclusion criteria are as following:

Refractory and secondary hypertension

Inclusion Criteria:

Patients diagnosed as refractory hypertension and/or secondary hypertension
Patients willing to accept long-term follow-up and regular return visits

Exclusion Criteria:

Severe diseases of other systems may affecting the life span of patients

Coronary heart disease

Inclusion Criteria:

Patients undergoing coronary angiography and interventional therapy in the cath lab
Patients undergoing coronary angiography and functional assessment in the cath lab
Patients diagnosed as acute myocardial infarction

Exclusion Criteria:

Severe diseases of other systems may affecting the life span of patients
Regular return visits not available

Atrial fibrillation

Inclusion Criteria:

PAtrial fibrillation diagnosed by electrocardiogram or holter (duration >30 seconds)
Patients willing to accept long-term follow-up and regular return visits

Exclusion Criteria:

Severe diseases of other systems may affecting the life span of patients
New-onset atrial fibrillation during the perioperative period of major surgery

Ventricular arrhythmias

Inclusion Criteria:

Patients diagnosed as ventricular tachycardia, ventricular premature beat
Patients willing to accept long-term follow-up and regular return visits

Exclusion Criteria:

Severe diseases of other systems may affecting the life span of patients
A transient cause of ventricular arrhythmia was determined by the doctor, and long-term follow-up was not required

Cardiac pacemaker implantation

Inclusion Criteria:

Patients with permanent pacemaker implantations due to various causes (including bradycardia pacing, implantable cardioverter defibrillator, cardiac resynchronization therapy, leadless cardiac pacemaker, etc.)
Patients willing to accept long-term follow-up and regular return visits

Exclusion Criteria:

Severe diseases of other systems may affecting the life span of patients

Structural heart disease

Inclusion Criteria:

Patients diagnosed as structural heart disease, including congenital heart disease and severe valvular disease (moderate and above valvular stenosis or incomplete closure)
Patients willing to accept long-term follow-up and regular return visits

Exclusion Criteria:

Severe diseases of other systems may affecting the life span of patients

Pulmonary hypertension

Inclusion Criteria:

Patients diagnosed as pulmonary hypertension
Patients willing to accept long-term follow-up and regular return visits

Exclusion Criteria:

Severe diseases of other systems may affecting the life span of patients

Heart failure

Inclusion Criteria:

Patients diagnosed as heart failure
Patients willing to accept long-term follow-up and regular return visits

Exclusion Criteria:

Severe diseases of other systems may affecting the life span of patients

Rare diseases of the cardiovascular system

Inclusion Criteria:

Patients diagnosed as rare diseases in the catalog published by National Health Commission of the People's Republic of China
Patients willing to accept long-term follow-up and regular return visits

Exclusion Criteria:

Severe diseases of other systems may affecting the life span of patients

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Division of Cardiology, Peking University First Hospital	Beijing	北京	China	100034

Sponsors and Collaborators

Peking University First Hospital

Investigators

None specified.

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

Responsible Party:

Jianping LI, Director of Department of Cardiology, Peking University First Hospital

ClinicalTrials.gov Identifier:

NCT04996342

Other Study ID Numbers:

CVDcohort

First Posted:

Aug 9, 2021

Last Update Posted:

Aug 9, 2021

Last Verified:

Aug 1, 2021

Studies a U.S. FDA-regulated Drug Product:

Studies a U.S. FDA-regulated Device Product:

Additional relevant MeSH terms:

Cardiovascular Diseases

Study Results

No Results Posted as of Aug 9, 2021