The Effect of Whole Body Cryotherapy on Recovery and Performance: a Randomized Controlled Trial

• Sponsor: University of Applied Sciences and Arts of Southern Switzerland (Other)
• Overall Status: Completed
• CT.gov ID: NCT02847663
• Collaborator: THIM - die internationale Hochschule für Physiotherapie (Other), Vrije Universiteit Brussel (Other)
• Enrollment: 30
• Location: 1
• Arms: 2
• Duration (Months): 26
• Patients Per Site Per Month: 1.2

Study Details

Study Description

Brief Summary

This study investigates the effects of whole-body cryotherapy vs. cold-water immersion after a muscle damage protocol.

Condition or Disease	Intervention/Treatment	Phase
Cold	Device: Kryosauna Space Cabin; Other: cold water tub	N/A

Detailed Description

In this study the effects of a single- or multiple whole body cryotherapy (-135°C for max. 2 minutes) vs. cold water immersion (10°C for 15 min) and a passive control group (20 min supine position) are compared. These effects are examined after a muscle damage protocol of the frontal thighs (3 x 30 jumps). The objective recovery parameters are vertical jump, maximum voluntary contraction of the anterior thigh muscle, heart rate, blood pressure, skin-core body temperature and the oxygen saturation of the thigh muscles. Subjective recovery parameters are the local muscle soreness details and the general exhaustion details. The parameters are directly and 24, 48 and measured 72 hours after exposure. The aim is to elicit the effects of whole body cooling to make recommendations to. The current scientific knowledge situation calls for further studies to whole body cooling.

Study Design

• Study Type: Interventional
• Actual Enrollment: 30 participants
• Allocation: Randomized
• Intervention Model: Parallel Assignment
• Masking: None (Open Label)
• Primary Purpose: Basic Science
• Official Title: The Effect of Whole Body Cryotherapy on Recovery and Performance: a Randomized Controlled Trial
• Study Start Date: Apr 1, 2016
• Actual Primary Completion Date: Mar 1, 2018
• Actual Study Completion Date: Jun 1, 2018

Arms and Interventions

Arm	Intervention/Treatment
Experimental: Whole-body cryotherapy The effects of whole-body cryotherapy (-135°C for 2 minutes) are investigated after a muscle damage protocol.	Device: Kryosauna Space Cabin; The whole body cryotherapy device is able to generatue temperatures up to -195°C for 3 minutes. In this study, we generate temperatures of -135°C for 2 minutes as proposed in the manual. The participant will enter the cabin in cold-resistant shoes and will remain in standing position during the whole procedure. The cold temperature is generated by vaporization of liquid nitrogen.; Other Names: Cryomed s.r.o.
Other: Cold-water immersion The effects of cold-water immersion (10°C for 15 minutes) are investigated after a muscle damage protocol.	Other: cold water tub; The tub will be filled with cold water up to the sternal level of the participants. Adding ice will ensure a constant temperature. The participant will sit inside the tub during the whole procedure.

Outcome Measures

Primary Outcome Measures

1. Vertical Jump [72 hours]

   Vertical Jump will be assessed in cm with the Just Jump Plate

2. Maximum voluntary contraction [72 hours]

   Maximum voluntary contraction will be assessed in kg on a custom made ergometer chair (COR 1)

3. Delayed onset of muscle soreness [72 hours]

   DOMS will be assessed using a visual analog scale (0-10 cm)

4. Ratings of perceived exertion [72 hours]

   RPE will be assessed using a BORG scale (6-20)

5. Skin temperature [60 minutes]

   Skin temperature of the neck, right scapula, right dorsal hand, right frontal thigh, right shin are assessed in °C using thermocouples (iButtons)

6. Core temperature [60 minutes]

   Core temperature will be assessed in °C via the ear

7. Cardiovascular measurements [60 min]

   Heart rate will be measured in beats per minute and bloop pressure will be measured in mm/Hg using an blood pressure monitor

8. Oxygenation of the right thigh muscle [60 min]

   Oxygenation of the right thigh muscle will be assessed in % using a near infrared spectometer.

Eligibility Criteria

Criteria

• Ages Eligible for Study: 18 Years to 35 Years
• Sexes Eligible for Study: All
• Accepts Healthy Volunteers: Yes

Inclusion Criteria:

Only healthy young subjects 18-35 years no musculoskeletal surgery in trunk and lower extremities injury history in trunk and lower extremity for more than one year subjects taking anticonceptive medication are allowed to participate

Exclusion Criteria:

Actual injuries or injuries for less than one year in trunk and /or lower extremities injury history in trunk and lower extremity for more than one year with complaints anxiety of cooling subjects on medication pace maker cardiovascular disease pregnancy skeletal problems appendectomy for less than two years Morbus Raynaud syndrome

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Fachhochschule Südschweiz	Landquart		Switzerland	7302

Sponsors and Collaborators

• University of Applied Sciences and Arts of Southern Switzerland
• THIM - die internationale Hochschule für Physiotherapie
• Vrije Universiteit Brussel

Investigators

• Principal Investigator: Ronaldus Clijsen, PhD, Fachhochschule Südschweiz

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

• Responsible Party: Ron Clijsen, PhD., University of Applied Sciences and Arts of Southern Switzerland
• ClinicalTrials.gov Identifier: NCT02847663
• Other Study ID Numbers: PB_2016-01125
• First Posted: Jul 28, 2016
• Last Update Posted: Aug 8, 2019
• Last Verified: Aug 1, 2019

• Individual Participant Data (IPD) Sharing Statement: No
• Plan to Share IPD: No
• Keywords provided by Ron Clijsen, PhD., University of Applied Sciences and Arts of Southern Switzerland: Cold; recovery

Study Results

No Results Posted as of Aug 8, 2019