Effects of Hydrolyzed Collagen and Vitamin C on Explosive Performance

Sponsor
PepsiCo Global R&D (Industry)
Overall Status
Completed
CT.gov ID
NCT04437758
Collaborator
(none)
50
1
2
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Study Details

Study Description

Brief Summary

Determine whether supplementation with a combined dose of 20 g of hydrolyzed collagen and 50 mg vitamin C, along with a power training exercise program, increases rate of force development (RFD) and performance in athletes

Condition or Disease Intervention/Treatment Phase
  • Dietary Supplement: Collagen and Vitamin C powder mix nutritional intervention
  • Other: Maltodextrin placebo powder
  • Other: Maximum power training exercise
N/A

Study Design

Study Type:
Interventional
Actual Enrollment :
50 participants
Allocation:
Randomized
Intervention Model:
Parallel Assignment
Masking:
Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Masking Description:
Sealed opaque packets coded by Sponsor's Product Development
Primary Purpose:
Basic Science
Official Title:
Effects of Hydrolyzed Collagen and Vitamin C on Explosive Performance
Actual Study Start Date :
Aug 22, 2019
Actual Primary Completion Date :
Feb 5, 2020
Actual Study Completion Date :
Feb 5, 2020

Arms and Interventions

Arm Intervention/Treatment
Experimental: Hydrolyzed collagen and Vitamin C powder mix

20 g hydrolyzed collagen + 50 mg vitamin C (ascorbic acid) pre-packed powder diluted in 250 ml (8 oz) of water

Dietary Supplement: Collagen and Vitamin C powder mix nutritional intervention
20 g collagen + 50 mg vitamin C daily, 60 min prior to exercise

Other: Maximum power training exercise
Explosive/power-based exercise training program 3 times/week at home consisting of drop jumps, box jumps, weighted jump squats loaded in a progressive manner weekly for 3 weeks. At baseline and at the end of each of the 3 weeks, measures of explosive performance are assessed in the lab (maximal isometric squat, counter-movement jump and squat jump)

Placebo Comparator: Maltodextrin powder

20 g maltodextrin pre-packed powder diluted in 250 ml (8 oz) of water

Other: Maltodextrin placebo powder
20 g maltodextrin placebo daily, 60 min prior to exercise

Other: Maximum power training exercise
Explosive/power-based exercise training program 3 times/week at home consisting of drop jumps, box jumps, weighted jump squats loaded in a progressive manner weekly for 3 weeks. At baseline and at the end of each of the 3 weeks, measures of explosive performance are assessed in the lab (maximal isometric squat, counter-movement jump and squat jump)

Outcome Measures

Primary Outcome Measures

  1. Maximal rate of force development (RFD) of isometric squat (MIS) [% change from baseline to week 1, week 2 and week 3]

    Force (N) over time (msec) for the maximum slope of the first 20% of the movement

  2. Counter-movement jump (CMJ) rate of force development (RFD) [% change from baseline to week 1, week 2 and week 3]

    CMJ jump performance N/s/kg

  3. Squat jump height rate of force development (RFD) [% change from baseline to week 1, week 2 and week 3]

    Squat jump height performance RFD/kg

Other Outcome Measures

  1. Maximum peak force of maximal isometric squat (MIS) [% change from baseline to week 1, week 2 and week 3]

    Peak force (N)

  2. Counter-movement jump (CMJ) net eccentric impulse [% change from baseline to week 1, week 2 and week 3]

    Jump performance max N/s/kg (Note: Eccentric is the drop down part of the CMJ)

  3. Counter-movement jump (CMJ) net concentric impulse [% change from baseline to week 1, week 2 and week 3]

    Jump performance max N/s/kg (Note: Concentric is the movement upwards of the CMJ)

  4. Leg stiffness assessment [% change from baseline to week 1, week 2 and week 3]

    Tendon stiffness mean per kg (N/m/kg)

Eligibility Criteria

Criteria

Ages Eligible for Study:
18 Years to 30 Years
Sexes Eligible for Study:
Male
Accepts Healthy Volunteers:
Yes
Inclusion Criteria:
  1. Healthy male athletes between 18-30 years of age

  2. Currently participating in sport

  3. <3 musculoskeletal injuries in the past year

  4. No health or dietary restriction that would be affected by the supplementation protocol

Exclusion Criteria:
  1. History of more than 3 musculoskeletal injuries within the past 12 months

  2. Health, dietary restriction or diet that would be affected by the supplementation protocol

  3. Willing to eat similar dietary pattern the day before baseline testing and each exercise testing/intervention day

Contacts and Locations

Locations

Site City State Country Postal Code
1 UC Davis Functional Molecular Biology Laboratory and Human Performance Laboratory Davis California United States 95616

Sponsors and Collaborators

  • PepsiCo Global R&D

Investigators

  • Principal Investigator: Keith Baar, PhD, University of California, Davis

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.
Responsible Party:
PepsiCo Global R&D
ClinicalTrials.gov Identifier:
NCT04437758
Other Study ID Numbers:
  • PEP-1704
First Posted:
Jun 18, 2020
Last Update Posted:
Jun 18, 2020
Last Verified:
Jun 1, 2020
Studies a U.S. FDA-regulated Drug Product:
No
Studies a U.S. FDA-regulated Device Product:
No
Keywords provided by PepsiCo Global R&D
Additional relevant MeSH terms:

Study Results

No Results Posted as of Jun 18, 2020