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Collection of Tumor Tissue, Blood and Spinal Fluid From Patients With Brain or Spine Tumors

Sponsor
Memorial Sloan Kettering Cancer Center (Other)
Overall Status
Completed
CT.gov ID
NCT00580463
Collaborator
Rockefeller University (Other)
1,128
Enrollment
1
Location
110
Duration (Months)
10.3
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The purpose of the study is to collect samples of brain or spine tumors. Memorial Sloan-Kettering Cancer Center would then store them for use by researchers who study brain or spine cancer and try to find better ways of treating it. We will also collect blood and spinal fluid from patients with brain or spine tumors. The blood and spinal fluids are also used for research studies of cancer and its treatment.

Condition or Disease Intervention/Treatment Phase

    Detailed Description

    The main objective of the protocol is the establishment of a repository of central nervous system (CNS) tumors or metastases to the CNS and related tissues as an invaluable resource for current or future research studies of the etiology, pathogenesis and treatment of human central nervous system tumors. The database will be established through the intra-operative acquisition of brain or spine tumors as well as the collection of blood and spinal fluids from consenting CNS tumor patients.

    Study Design

    Study Type:
    Observational
    Actual Enrollment :
    1128 participants
    Observational Model:
    Case-Only
    Time Perspective:
    Prospective
    Official Title:
    Collection of Tumor Tissue, Blood and Spinal Fluid From Patients With Brain or Spine Tumors
    Study Start Date :
    Jan 1, 2000
    Actual Primary Completion Date :
    Mar 1, 2009
    Actual Study Completion Date :
    Mar 1, 2009

    Outcome Measures

    Primary Outcome Measures

    1. To establish a repository of CNS tumors or metastases to the CNS and related tissues for current or future studies. [conclusion of the study]

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    N/A and Older
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    No
    Inclusion Criteria:

    • For acquisition of intra-operative brain or spine tumor specimens, blood specimens and spinal fluid specimens, all patients who undergo surgery for resection or biopsy qualify for inclusion in this protocol.

    • If spinal fluid is not accessed as part of the operative procedure, it will not be collected.

    • All patients must be under the care of one or more members of the MSKCC CNS disease management team at the time of tissue acquisition. Patients may have been previously diagnosed and/or treated at another institution.

    • Subjects are eligible regardless of sex, age or race.

    • Parental or guardian consents will be obtained in the case of minors (less than 18 years of age)

    Exclusion Criteria:

    • Patients or their guardians, in case of a minor, may choose to be excluded at any time.

    • If a patient, or guardian, decides to withdraw after some or all of the tissues have been collected, such tissues will be destroyed at their request.

    • Patients or their guardians will be counseled at the time of obtaining their consent, of the possibility of withdrawing from the protocol.

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Memorial Sloan-Kettering Cancer Center New York New York United States 10065

    Sponsors and Collaborators

    • Memorial Sloan Kettering Cancer Center
    • Rockefeller University

    Investigators

    • Principal Investigator: Philip Gutin, MD, Memorial Sloan Kettering Cancer Center

    Study Documents (Full-Text)

    None provided.

    More Information

    Additional Information:

    Publications

    None provided.
    Responsible Party:
    , ,
    ClinicalTrials.gov Identifier:
    NCT00580463
    Other Study ID Numbers:
    • 99-125
    First Posted:
    Dec 24, 2007
    Last Update Posted:
    Mar 19, 2009
    Last Verified:
    Mar 1, 2009
    Keywords provided by , ,
    central nervous system (CNS) tumor
    tissue collection
    Additional relevant MeSH terms:
    Neoplasms

    Study Results

    No Results Posted as of Mar 19, 2009