The Efficacy of Color-Doppler Ultrasonography to Assess the Renal Blood Flow With the Estimation of GFR

Sponsor

University of Roma La Sapienza (Other)

Overall Status

Unknown status

CT.gov ID

NCT00470769

Collaborator

(none)

2,006

Enrollment

Locations

Duration (Months)

668.7

Patients Per Site

84.1

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

It is generally assumed that renal blood flow is symmetric in the absence of renal artery stenosis. The importance of studying the function of both kidneys separately is because it cannot be assumed that they are functionally equal.The aim of the present study is to evaluate whether this is really in patients with essential hypertension and/or moderate kidneys loss.

Condition or Disease	Intervention/Treatment	Phase
Hypertension Renal Failure	Procedure: Color-Doppler Ultrasound, 99mTc-DTPA scintigraphy

Detailed Description

To validate color Doppler ultrasonography of renal arteries for the assessment of renal blood flow (RBF), we comparing left and right RBF estimates and their sum (total RBF) by echo-Doppler with data obtained by 99mTc-DTPA scintigraphy in 50 patients with hypertension and/or moderate renal failure, compared with 30 normal control subjects.

Study Design

Study Type:

Observational

Anticipated Enrollment :

2006 participants

Observational Model:

Defined Population

Time Perspective:

Other

Official Title:

Color-Doppler Ultrasonography vs 99mTc-DTPA Scintigraphy to Assess the Renal Blood Flow

Study Start Date :

Sep 1, 2006

Anticipated Study Completion Date :

May 1, 2007

Outcome Measures

Primary Outcome Measures

Eligibility Criteria

Criteria

Ages Eligible for Study:

30 Years to 80 Years

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Yes

Inclusion Criteria:

Patients with hypertension
Patients with moderate renal insufficiency
Normal subjects

Exclusion Criteria:

Patients with solitary kidney function
Patients with renal artery stenosis
Patients underwent renal angioplasty and stenting

Contacts and Locations

Locations

	Site	City	Country	Postal Code
1	Giorgio Fuiano	Catanzaro	Italy	88020
2	University of Rome La Sapienza	Roma	Italy	00100
3	Rosario Cianci	Rome	Italy	00100

Sponsors and Collaborators

University of Roma La Sapienza

Investigators

Principal Investigator: Rosario Cianci, MD, Department Of Clinic Medicine, Chair of Nephrology
Study Director: Giorgio Fuiano, MD, University of Catanzaro