CogPhyAero: Combined Effects of Acute Sleep Restriction and Moderate Acceleration (+Gz) on Physiological and Behavioral Responses to High Mental Workload
Study Details
Study Description
Brief Summary
Fighter pilots have to perform tasks requiring high mental workload during moderate-intensity acceleration phases (2 to 3G) that can last several minutes. When these accelerations are performed in the body axis (+Gz), they induce a redistribution of blood flow in the lower limbs associated with a decrease in cerebral blood flow, partially compensated by activation of the sympathetic nervous system (baroreflex).
The main hypothesis is that the effects of these prolonged accelerations, even of moderate intensity (<+4Gz), could impair pilots' ability to perform complex cognitive tasks, with potential consequences for flight safety and mission conduct.
Moreover, flight missions are often performed after sleep debt, which is known to induce cardiovascular responses, sympathetic nervous system activation and impaired mental performance.
The secondary hypothesis is that sleep debt (3h of time spent in bed) may increase the impairment of cognitive performance during prolonged acceleration.
| Condition or Disease | Intervention/Treatment | Phase |
|---|---|---|
|
Study Design
Arms and Interventions
| Arm | Intervention/Treatment |
|---|---|
| Group A : Usual sleep *2 ; Deprivation *2 V1->V3 id. V4 : Usual sleep and test series (easy; difficult; difficult) V5 : Usual sleep and test series (difficult; easy; easy) V6 : Sleep deprivation and test series (easy; easy; difficult) V7 : Sleep deprivation and test series (difficult; difficult; easy) |
Other: Partial sleep deprivation
|
| Group B : Usual sleep ; Deprivation; Deprivation ; Usual sleep V1->V3 id. V4 : Usual sleep and test series ( difficult; difficult ; easy) V5 : Sleep deprivation and test series (easy; difficult; difficult) V6 : Sleep deprivation and test series (difficult; easy; easy) V7 : Usual sleep and test series (easy ; easy ; difficult) |
Other: Partial sleep deprivation
|
| Group C : Deprivation; Usual sleep ; Deprivation ; Usual sleep V1->V3 id. V4 : Sleep deprivation and test series (easy; easy; difficult) V5 : Usual sleep and test series (difficult; difficult; easy) V6 : Sleep deprivation and test series (easy; difficult; difficult) V7 : Usual and test series (difficult; easy; easy) |
Other: Partial sleep deprivation
|
| Group D : Deprivation ; Deprivation ; Usual sleep ; Usual sleep V1->V3 id. V4 : Sleep deprivation and test series (difficult; easy; easy) V5 : Sleep deprivation and test series (easy; difficult; easy) V6 : Usual sleep and test series ( difficult; easy ; easy) V7 : Usual sleep and test series (easy ; difficult; difficult) |
Other: Partial sleep deprivation
|
Outcome Measures
Primary Outcome Measures
- Difference in average tracking accuracy on the simulator MATB-II depending on centrifuge acceleration (quantitative measurement) [Through study completion (26 months)]
MATB-II (Multi Attribute Task Battery) is a complex task simulator that mimics realistic tasks commonly performed by aircraft pilots during flight. Among these tasks, target tracking involves positioning a reticle at the center of the simulator's artificial horizon. The variance of the reticle's position as a function of the acceleration received in the centrifuge will be the primary outcome mesure in this study. This is a quantitative measure provided by the simulator.
Eligibility Criteria
Criteria
Inclusion Criteria:
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Healthy subject (male or female);
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Tobacco consumption < 5 cigarettes per day or nicotine-free vapour;
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Regular physical activity (between 1 and 8 hours per week);
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Affiliated or entitled to a social security scheme;
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Having given their consent.
Exclusion Criteria:
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Presenting an active medical pathology or a history <6 months (cardiological, renal, hepatic, cutaneous, neurological, psychiatric...), or a significant deviation from normal values observed during questioning, clinical examination or electrocardiogram (ECG);
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BMI > 30 (cardiovascular risk factor);
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Have a medical contraindication to sporting activities;
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Taking a medical treatment;
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Habitual sleep duration < 6 hours;
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Presenting a sleep disorder confirmed by questionnaire (Pittsburgh Sleep Quality Index Questionnaire > 5);
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Pregnant or breastfeeding
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Not covered by a health insurance plan;
Contacts and Locations
Locations
| Site | City | State | Country | Postal Code | |
|---|---|---|---|---|---|
| 1 | Institut de Recherche Biomédicale des Armées | Brétigny-sur-Orge | France | 91223 |
Sponsors and Collaborators
- Direction Centrale du Service de Santé des Armées
Investigators
None specified.Study Documents (Full-Text)
None provided.More Information
Publications
None provided.- 2023PBMD06
- 2023-A01101-44