Comparison Imaging System Between Spatially Modulated Quantitative Spectroscopy and Skin Spect Dermoscopy

Sponsor

University of California, Irvine (Other)

Overall Status

Withdrawn

CT.gov ID

NCT02473874

Collaborator

Beckman Laser Institute University of California Irvine (Other)

Enrollment

Location

Duration (Months)

Patients Per Site Per Month

Study Details

Study Description

Brief Summary

The purpose of this study is to obtain skin spectroscopic data from two imaging systems.

Comparison groups:

Skin Spect dermoscope
Spatially modulated quantitative spectrometer

Condition or Disease	Intervention/Treatment	Phase
Melanocytic Nevus	Device: Skin Spect dermoscope Device: Spatially modulated quantitative

Detailed Description

The researcher can compare the spectroscopic data from the two systems as well as the relative concentrations of melanin, oxy- and deoxy- hemoglobin calculated from the measurements.

Skin Spect can measure larger area of skin, whereas Spatially modulated quantitative spectrometer is a point-based measurement.Therefore, larger nevi will require multiple Spatially modulated quantitative spectrometer measurements for comparison with corresponding sub-regions of the larger Skin Spect measurements. Only sub-regions of the image data from Skin Spect that match the locations Spatially modulated quantitative spectrometer acquired data will be used in this correlation study.

This researcher ensure that the spectral data collected by the two instruments are collected from the same spatial locations, should lesion heterogeneity be present.

Study Design

Study Type:

Observational

Actual Enrollment :

0 participants

Observational Model:

Case-Control

Time Perspective:

Prospective

Official Title:

Spectral Comparison Between Spatially Modulated Quantitative Spectroscopy and Polarization-Sensitive Hyperspectral Multimode Dermoscopy for the Purpose of Skin Compositional Analysis

Study Start Date :

Jun 1, 2015

Actual Primary Completion Date :

Jan 1, 2020

Actual Study Completion Date :

Jan 1, 2020

Arms and Interventions

Arm	Intervention/Treatment
Skin Spect dermoscope Skin mole	Device: Skin Spect dermoscope Skin imaging
Spatially modulated quantitative Skin mole	Device: Spatially modulated quantitative Skin imaging

Arm

Intervention/Treatment

Skin Spect dermoscope

Skin mole

Device: Skin Spect dermoscope

Skin imaging

Spatially modulated quantitative

Skin mole

Device: Spatially modulated quantitative

Skin imaging

Outcome Measures

Primary Outcome Measures

Changes in human skin structure [up to 12 weeks]
Comparison Imaging Changes in human skin structure Between Spatially Modulated Quantitative Spectroscopy and Skin Spect Dermoscopy

Eligibility Criteria

Criteria

Ages Eligible for Study:

18 Years and Older

Sexes Eligible for Study:

All

Accepts Healthy Volunteers:

Yes

Inclusion Criteria:

Skin lesion a mole located on flat surface of the body

Exclusion Criteria:

Mole located on complex surface
Pregnant women

Contacts and Locations

Locations

	Site	City	State	Country	Postal Code
1	Beckman Laser Institute	Irvine	California	United States	92612

Sponsors and Collaborators

University of California, Irvine
Beckman Laser Institute University of California Irvine

Investigators

Principal Investigator: Kristen Kelly, MD, Beckman Laser Institute, UCI

Study Documents (Full-Text)

None provided.

More Information

Publications

None provided.

Responsible Party:

Beckman Laser Institute and Medical Center, Kristen Kelly, M.D., Professor of Dermatology and Surgery, University of California, Irvine

ClinicalTrials.gov Identifier:

NCT02473874

Other Study ID Numbers:

NIH-LAMPP-SBIR-2015-1791

First Posted:

Jun 17, 2015

Last Update Posted:

Apr 30, 2020

Last Verified:

Apr 1, 2020

Additional relevant MeSH terms:

Nevus, Pigmented

Nevus

Study Results

No Results Posted as of Apr 30, 2020