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Comparison of On-line and Off-line Measurements of Exhaled Nitric Oxide (NO)

Sponsor
Ziv Hospital (Other)
Overall Status
Unknown status
CT.gov ID
NCT00686309
Collaborator
(none)
200
Enrollment
1
Location
12
Duration (Months)
16.7
Patients Per Site Per Month

Study Details

Study Description

Brief Summary

Asthma is a major health problem worldwide. The measurement of fractional exhaled nitric oxide (FENO) has been established as a valuable non invasive and simple tool in the diagnosis of asthma and may also act as a useful surrogate inflammatory marker on which to base treatment decisions in asthma management algorithms. The measurement is useful also in other respiratory diseases. Current methods of measuring FENO include on line measurements by heavy duty expensive analyzers which are not widely and easily available. Off line measurements of breath samples which can be analysed later may be a simple solution. We hypothesize tha toff line measurements of NO will be as reliable and valid as those measured on-line

Condition or Disease Intervention/Treatment Phase

    Study Design

    Study Type:
    Observational
    Anticipated Enrollment :
    200 participants
    Observational Model:
    Case-Crossover
    Time Perspective:
    Prospective
    Official Title:
    Comparison of On-line and Off-line Measurements of Exhaled NO
    Study Start Date :
    Jul 1, 2010
    Anticipated Primary Completion Date :
    Jul 1, 2011
    Anticipated Study Completion Date :
    Jul 1, 2011

    Outcome Measures

    Primary Outcome Measures

    1. Off line measurement of exhaled NO [Two types of breathing in the same day]

    Eligibility Criteria

    Criteria

    Ages Eligible for Study:
    N/A and Older
    Sexes Eligible for Study:
    All
    Accepts Healthy Volunteers:
    Yes
    Inclusion Criteria:

    • Volunteer to participate

    • Filed a short health questionnaire

    Exclusion Criteria:
    • None

    Contacts and Locations

    Locations

    Site City State Country Postal Code
    1 Pediatric Department, Ziv Medical Center Safed Israel

    Sponsors and Collaborators

    • Ziv Hospital

    Investigators

    None specified.

    Study Documents (Full-Text)

    None provided.

    More Information

    Publications

    None provided.
    Responsible Party:
    , ,
    ClinicalTrials.gov Identifier:
    NCT00686309
    Other Study ID Numbers:
    • HP8-295-R
    First Posted:
    May 29, 2008
    Last Update Posted:
    Aug 18, 2009
    Last Verified:
    Aug 1, 2009
    Keywords provided by , ,
    exhaled NO
    off line
    on line
    comparison
    Bland altman method
    Additional relevant MeSH terms:
    Ciliary Motility Disorders
    Dyskinesias

    Study Results

    No Results Posted as of Aug 18, 2009